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High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser

Understanding brain dynamics and functions critically depends on knowledge of the network connectivity among neurons. However, the complexity of brain structural connectivity, coupled with continuous modifications driven by synaptic…

Neurons and Cognition · Quantitative Biology 2025-07-04 Kai Chen , Mingzhang Wang , Songting Li , Douglas Zhou

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

Neurons and Cognition · Quantitative Biology 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

We consider an excitatory random network of leaky integrate-and-fire pulse coupled neurons. The neurons are connected as in a directed Erd\"os-Renyi graph with average connectivity $<k>$ scaling as a power law with the number of neurons in…

Disordered Systems and Neural Networks · Physics 2012-08-28 Lorenzo Tattini , Simona Olmi , Alessandro Torcini

Growing attention has been brought to the fact that many real directed networks exhibit hierarchy and directionality as measured through techniques like Trophic Analysis and non-normality. We propose a simple growing network model where the…

Physics and Society · Physics 2024-05-13 Niall Rodgers , Peter Tino , Samuel Johnson

Hierarchical tree structures are common in many real-world systems, from tree roots and branches to neuronal dendrites and biologically inspired artificial neural networks, as well as in technological networks for organizing and searching…

Statistical Mechanics · Physics 2025-02-04 Davide Cipollini , Lambert Schomaker

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

Network science has been applied widely to study brain network organization, especially at the meso-scale, where nodes represent brain areas and edges reflect interareal connectivity inferred from imaging or tract-tracing data. While this…

Neurons and Cognition · Quantitative Biology 2025-08-26 Richard Betzel , Caio Seguin , Maria Grazia Puxeddu

Understanding how different networks relate to each other is key for obtaining a greater insight into complex systems. Here, we introduce an intuitive yet powerful framework to characterise the relationship between two networks comprising…

Social and Information Networks · Computer Science 2023-08-09 Andrea I. Luppi , Eckehard Olbrich , Conor Finn , Laura E. Suárez , Fernando E. Rosas , Pedro A. M. Mediano , Jürgen Jost

A fundamental understanding of the network architecture of the brain is necessary for the further development of theories explicating circuit function. Perhaps as a derivative of its initial application to abstract informational systems,…

Neurons and Cognition · Quantitative Biology 2018-07-13 Jennifer Stiso , Danielle Bassett

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

Neurons and Cognition · Quantitative Biology 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

The emergence of detailed maps of physical networks, like the brain connectome, vascular networks, or composite networks in metamaterials, whose nodes and links are physical entities, have demonstrated the limits of the current network…

Functional brain connectivity changes dynamically over time, making its representation challenging for learning on non-Euclidean data. We present a framework that encodes dynamic functional connectivity as an image representation of…

Neurons and Cognition · Quantitative Biology 2025-11-14 Peilin He , Tananun Songdechakraiwut

The network representation is becoming increasingly popular for the description of cardiovascular interactions based on the analysis of multiple simultaneously collected variables. However, the traditional methods to assess network links…

Objective: Brain is a fantastic organ that helps creature adapting to the environment. Network is the most essential structure of brain, but the capability of a simple network is still not very clear. In this study, we try to expound some…

Neurons and Cognition · Quantitative Biology 2019-11-05 Xiang Zou , Lie Yao , Donghua Zhao , Liang Chen , Ying Mao

How neurons integrate the myriad synaptic inputs scattered across their dendrites is a fundamental question in neuroscience. Multiple neurophysiological experiments have shown that dendritic non-linearities can have a strong influence on…

Neurons and Cognition · Quantitative Biology 2025-01-13 Clarissa Lauditi , Enrico M. Malatesta , Fabrizio Pittorino , Carlo Baldassi , Nicolas Brunel , Riccardo Zecchina

Cross-entropy loss has long been the standard choice for training deep neural networks, yet it suffers from interpretability limitations, unbounded weight growth, and inefficiencies that can contribute to costly training dynamics. The…

Machine Learning · Computer Science 2026-04-30 Maxwell Miller-Golub , Collin Coil , Kamil Faber , Marcin Pietron , Panpan Zheng , Pasquale Minervini , Roberto Corizzo

Several approaches to cognition and intelligence research rely on statistics-based models testing, namely factor analysis. In the present work we exploit the emerging dynamical systems perspective putting the focus on the role of the…

Physics and Society · Physics 2018-03-15 Gemma Rosell-Tarragó , Emanuele Cozzo , Albert Díaz-Guilera

We consider a Gaussian statistical model whose parameter space is given by the variances of random variables. Underlying this model we identify networks by interpreting random variables as sitting on vertices and their correlations as…

Mathematical Physics · Physics 2015-06-17 Domenico Felice , Stefano Mancini , Marco Pettini

Principles of network topology have been widely studied in the human connectome. Of particular interest is the modularity of the human brain, where the connectome is divided into subnetworks and subsequently changes with development, aging…

Neurons and Cognition · Quantitative Biology 2019-02-05 Markus D. Schirmer , Ai Wern Chung , P. Ellen Grant , Natalia S. Rost