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In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

Condensed Matter · Physics 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

Proliferating cell collectives often develop an active growth layer near their boundary that regulates expansion and morphology, as observed in systems ranging from bacterial biofilms to epithelial tissues and tumor spheroids. While such…

Soft Condensed Matter · Physics 2026-04-27 Fidel Álvarez-Murphy , Ignacio Medina , Néstor Sepúlveda , Gustavo Düring

We develop a Bayesian graphical modeling framework for functional data for correlated multivariate random variables observed over a continuous domain. Our method leads to graphical Markov models for functional data which allows the graphs…

Mechanical stresses stemming from environmental factors are a key determinant of cellular behavior and physiology. Yet, the role of self-induced biomechanical stresses in growing bacterial colonies has remained largely unexplored. Here, we…

Soft Condensed Matter · Physics 2023-11-27 René Wittmann , G. H. Philipp Nguyen , Hartmut Löwen , Fabian J. Schwarzendahl , Anupam Sengupta

Cox proportional hazards model is one of the most popular models in biomedical data analysis. There have been continuing efforts to improve the flexibility of such models for complex signal detection, for example, via additive functions.…

Methodology · Statistics 2022-05-25 Boyi Guo , Nengjun Yi

We propose a novel stochastic model for the spread of antimicrobial-resistant bacteria in a population, together with an efficient algorithm for fitting such a model to sample data. We introduce an individual-based model for the epidemic,…

We propose an end-to-end-trainable feature augmentation module built for image classification that extracts and exploits multi-view local features to boost model performance. Different from using global average pooling (GAP) to extract…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Xiang Gao , Yingjie Tian , Zhiquan Qi

Logistic regression (LR) is widely used in clinical prediction because it is simple to deploy and easy to interpret. Nevertheless, being a linear model, LR has limited expressive capability and often has unsatisfactory performance.…

Machine Learning · Computer Science 2019-07-31 Zhicheng Cui , Bradley A Fritz , Christopher R King , Michael S Avidan , Yixin Chen

Gradient boosting is widely popular due to its flexibility and predictive accuracy. However, statistical inference and uncertainty quantification for gradient boosting remain challenging and under-explored. We propose a unified framework…

Machine Learning · Statistics 2025-09-30 Haimo Fang , Kevin Tan , Giles Hooker

We introduce GAMSEL (Generalized Additive Model Selection), a penalized likelihood approach for fitting sparse generalized additive models in high dimension. Our method interpolates between null, linear and additive models by allowing the…

Machine Learning · Statistics 2015-06-18 Alexandra Chouldechova , Trevor Hastie

In epidemic modeling, outliers can distort parameter estimation and ultimately lead to misguided public health decisions. Although there are existing robust methods that can mitigate this distortion, the ability to simultaneously detect…

Methodology · Statistics 2025-07-15 Haoming Shi , Shan Yu , Eric C. Chi

Practical Bayesian learning often requires (1) online inference, (2) dynamic models, and (3) ensembling over multiple different models. Recent advances have shown how to use random feature approximations to achieve scalable, online…

Machine Learning · Computer Science 2024-05-03 Daniel Waxman , Petar M. Djurić

We propose a new framework of XGBoost that predicts the entire conditional distribution of a univariate response variable. In particular, XGBoostLSS models all moments of a parametric distribution (i.e., mean, location, scale and shape…

Machine Learning · Statistics 2019-08-27 Alexander März

The joint modeling of longitudinal and time-to-event data is an important tool of growing popularity to gain insights into the association between a biomarker and an event process. We develop a general framework of flexible additive joint…

Originally motivated by the morphogenesis of bacterial microcolonies, the aim of this article is to explore models through different scales for a spatial population of interacting, growing and dividing particles. We start from a microscopic…

Analysis of PDEs · Mathematics 2025-01-07 Marie Doumic , Sophie Hecht , Marc Hoffmann , Diane Peurichard

Additive models and generalized additive models are effective semiparametric tools for multidimensional data. In this article we propose an online smoothing backfitting method for generalized additive models with local polynomial smoothers.…

Statistics Theory · Mathematics 2021-12-20 Ying Yang , Fang Yao

Feature generation is an open topic of investigation in graph machine learning. In this paper, we study the use of graph homomorphism density features as a scalable alternative to homomorphism numbers which retain similar theoretical…

Machine Learning · Computer Science 2021-04-12 Paul Beaujean , Florian Sikora , Florian Yger

Boosting is a generic learning method for classification and regression. Yet, as the number of base hypotheses becomes larger, boosting can lead to a deterioration of test performance. Overfitting is an important and ubiquitous phenomenon,…

Machine Learning · Statistics 2015-10-12 Chu Wang , Yingfei Wang , Weinan E , Robert Schapire

Growth mixture models (GMMs) incorporate both conventional random effects growth modeling and latent trajectory classes as in finite mixture modeling; therefore, they offer a way to handle the unobserved heterogeneity between subjects in…

Methodology · Statistics 2017-11-15 Yuhong Wei , Yang Tang , Emilie Shireman , Paul D. McNicholas , Douglas L. Steinley

We propose a regression model in which the responses are spherical variables and the covariates include linear and/or spherical variables. A novel link function is introduced by extending the M\"obius transformation on the sphere. This link…

Methodology · Statistics 2025-09-09 Shogo Kato , Kassel L. Hingee , Janice L. Scealy , Andrew T. A. Wood