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Method comparison studies explore the agreement of measurements made by two or more methods. Commonly, agreement is evaluated by the well-established Bland-Altman analysis. However, the underlying assumption is that differences between…

Methodology · Statistics 2023-06-08 Siranush Karapetyan , Achim Zeileis , André Henriksen , Alexander Hapfelmeier

Background: In clinical research, the Bland-Altman analysis is commonly used to assess agreement of metric measurements made by two or more techniques, devices or methods. The approach can also deal with repeated measurements per subject or…

Multiple raters are often needed to be used interchangeably in practice for measurement or evaluation. Assessing agreement among these multiple raters via agreement indices are necessary before their participation. While the intuitively…

Methodology · Statistics 2020-06-09 Tongrong Wang , Huiman X. Barnhart

Agreement between measurement methods is commonly investigated by a so-called Bland-Altman plot showing if the difference is independent of the size of the measurement. However, such analysis assumes that both methods have the same…

Methodology · Statistics 2022-12-23 Magnus Borga

Agreement coefficients provide a fundamental framework for quantifying the concordance between two or more measurement methods applied to the same continuous variable. Unlike correlation, which measures the strength of a linear…

Methodology · Statistics 2026-04-28 Ronny Vallejos

Measurement of the interrater agreement (IRA) is critical in various disciplines. To correct for potential confounding chance agreement in IRA, Cohen's kappa and many other methods have been proposed. However, owing to the varied strategies…

Methodology · Statistics 2024-02-14 Zizhong Tian , Vernon M. Chinchilli , Chan Shen , Shouhao Zhou

Participant level meta-analysis across multiple studies increases the sample size for pooled analyses, thereby improving precision in effect estimates and enabling subgroup analyses. For analyses involving biomarker measurements as an…

A method is discussed that allows combining sets of differential or inclusive measurements. It is assumed that at least one measurement was obtained with simultaneously fitting a set of nuisance parameters, representing sources of…

Data Analysis, Statistics and Probability · Physics 2018-01-09 Jan Kieseler

Before new clinical measurement methods are implemented in clinical practice, it must be confirmed whether their results are equivalent to those of existing methods. The agreement of the trend between these methods is evaluated using the…

Methodology · Statistics 2021-03-01 Mayu Hiraishi , Kensuke Tanioka , Toshio Shimokawa

Objective: Bland and Altman plot method is a widely cited and applied graphical approach for assessing the equivalence of quantitative measurement techniques, usually aiming to replace a traditional technique with a new, less invasive, or…

Methodology · Statistics 2023-07-04 P. S. P. Silveira , J. E. Vieira , J. O. Siqueira

This paper proposes a framework for evaluating the statistical precision of measurement methods from interlaboratory studies where the outcome is a dose-response relationship summarized by a regression line. For such measurement methods,…

Applications · Statistics 2026-05-13 Jun-ichi Takeshita , Yuto Ikeuchi , Tomomichi Suzuki

In this work, we addressed the issue of applying a stochastic classifier and a local, fuzzy confusion matrix under the framework of multi-label classification. We proposed a novel solution to the problem of correcting label pairwise…

Machine Learning · Computer Science 2018-02-08 Pawel Trajdos , Marek Kurzynski

An ensemble method should cleverly combine a group of base classifiers to yield an improved classifier. The majority vote is an example of a methodology used to combine classifiers in an ensemble method. In this paper, we propose to combine…

Machine Learning · Computer Science 2020-09-21 Rodolfo Anibal Lobo , Marcos Eduardo Valle

Considerable interest has recently been focused on studying multiple phenotypes simultaneously in both epidemiological and genomic studies, either to capture the multidimensionality of complex disorders or to understand shared etiology of…

Methodology · Statistics 2015-11-26 Denis Agniel , Katherine P. Liao , Tianxi Cai

In many applied sciences a popular analysis strategy for high-dimensional data is to fit many multivariate generalized linear models in parallel. This paper presents a novel approach to address the resulting multiple testing problem by…

Statistics Theory · Mathematics 2024-10-07 Riccardo De Santis , Jelle J. Goeman , Samuel Davenport , Jesse Hemerik , Livio Finos

Gathering observational data for medical decision-making often involves uncertainties arising from both type I (false positive)and type II (false negative) errors. In this work, we develop a statistical model to study how medical…

Applications · Statistics 2025-10-21 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

While multiple testing procedures have been the focus of much statistical research, an important facet of the problem is how to deal with possible confounding. Procedures have been developed by authors in genetics and statistics. In this…

Methodology · Statistics 2008-12-18 Debashis Ghosh

Valid estimation of treatment effects from observational data requires proper control of confounding. If the number of covariates is large relative to the number of observations, then controlling for all available covariates is infeasible.…

Methodology · Statistics 2018-01-11 Joseph Antonelli , Matthew Cefalu , Nathan Palmer , Denis Agniel

To date, testing interactions in high dimensions has been a challenging task. Existing methods often have issues with sensitivity to modeling assumptions and heavily asymptotic nominal p-values. To help alleviate these issues, we propose a…

Machine Learning · Statistics 2012-06-29 Noah Simon , Robert Tibshirani

Consider the problem of estimating average treatment effects when a large number of covariates are used to adjust for possible confounding through outcome regression and propensity score models. The conventional approach of model building…

Statistics Theory · Mathematics 2018-01-31 Zhiqiang Tan
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