English
Related papers

Related papers: EpiRL: A Reinforcement Learning Agent to Facilitat…

200 papers

As the amount and complexity of genetic information increases it is necessary that we explore some efficient ways of handling these data. This study takes the "divide and conquer" approach for analyzing high dimensional genomic data. Our…

Applications · Statistics 2013-08-15 Deniz Akdemir

Deep reinforcement learning (RL) algorithms frequently require prohibitive interaction experience to ensure the quality of learned policies. The limitation is partly because the agent cannot learn much from the many low-quality trials in…

Machine Learning · Computer Science 2020-04-24 Keting Lu , Shiqi Zhang , Xiaoping Chen

Epistasis can be defined as the statistical interaction of genes during the expression of a phenotype. It is believed that it plays a fundamental role in gene expression, as individual genetic variants have reported a very small increase in…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-09 Christian Ponte-Fernández , Jorge González-Domínguez , María J. Martín

We propose a novel reinforcement learning-based approach for adaptive and iterative feature selection. Given a masked vector of input features, a reinforcement learning agent iteratively selects certain features to be unmasked, and uses…

Machine Learning · Computer Science 2020-05-26 Uri Shaham , Tom Zahavy , Cesar Caraballo , Shiwani Mahajan , Daisy Massey , Harlan Krumholz

We propose a new method for event extraction (EE) task based on an imitation learning framework, specifically, inverse reinforcement learning (IRL) via generative adversarial network (GAN). The GAN estimates proper rewards according to the…

Computation and Language · Computer Science 2018-04-24 Tongtao Zhang , Heng Ji

Approaches based on generative adversarial networks for imitation learning are promising because they are sample efficient in terms of expert demonstrations. However, training a generator requires many interactions with the actual…

Machine Learning · Computer Science 2022-09-01 Eiji Uchibe

We introduce a multi-agent meta-modeling game to generate data, knowledge, and models that make predictions on constitutive responses of elasto-plastic materials. We introduce a new concept from graph theory where a modeler agent is tasked…

Machine Learning · Computer Science 2020-04-15 Kun Wang , WaiChing Sun , Qiang Du

One component of precision medicine is to construct prediction models with their predictive ability as high as possible, e.g. to enable individual risk prediction. In genetic epidemiology, complex diseases have a polygenic basis and a…

Machine Learning · Statistics 2019-01-28 Damian Gola , Inke R. König

High-dimensional biomarkers such as genomics are increasingly being measured in randomized clinical trials. Consequently, there is a growing interest in developing methods that improve the power to detect biomarker-treatment interactions.…

Methodology · Statistics 2021-04-30 Jixiong Wang , Ashish Patel , James M. S. Wason , Paul J. Newcombe

Many reinforcement learning (RL) environments consist of independent entities that interact sparsely. In such environments, RL agents have only limited influence over other entities in any particular situation. Our idea in this work is that…

Machine Learning · Computer Science 2021-12-03 Maximilian Seitzer , Bernhard Schölkopf , Georg Martius

Learning agents can make use of Reinforcement Learning (RL) to decide their actions by using a reward function. However, the learning process is greatly influenced by the elect of values of the hyperparameters used in the learning…

Robotics · Computer Science 2022-11-03 Adarsh Sehgal , Nicholas Ward , Hung La , Sushil Louis

Dataset biases are notoriously detrimental to model robustness and generalization. The identify-emphasize paradigm appears to be effective in dealing with unknown biases. However, we discover that it is still plagued by two challenges: A,…

Machine Learning · Computer Science 2023-02-23 Bowen Zhao , Chen Chen , Qian-Wei Wang , Anfeng He , Shu-Tao Xia

Reinforcement learning (RL) algorithms update an agent's parameters according to one of several possible rules, discovered manually through years of research. Automating the discovery of update rules from data could lead to more efficient…

Machine Learning · Computer Science 2021-01-06 Junhyuk Oh , Matteo Hessel , Wojciech M. Czarnecki , Zhongwen Xu , Hado van Hasselt , Satinder Singh , David Silver

Applying deep reinforcement learning (RL) on real systems suffers from slow data sampling. We propose an enhanced generative adversarial network (EGAN) to initialize an RL agent in order to achieve faster learning. The EGAN utilizes the…

Artificial Intelligence · Computer Science 2017-05-30 Vincent Huang , Tobias Ley , Martha Vlachou-Konchylaki , Wenfeng Hu

Inverse Reinforcement Learning (IRL) describes the problem of learning an unknown reward function of a Markov Decision Process (MDP) from observed behavior of an agent. Since the agent's behavior originates in its policy and MDP policies…

Artificial Intelligence · Computer Science 2016-04-14 Michael Herman , Tobias Gindele , Jörg Wagner , Felix Schmitt , Wolfram Burgard

Empathetic response generation, aiming to understand the user's situation and feelings and respond empathically, is crucial in building human-like dialogue systems. Traditional approaches typically employ maximum likelihood estimation as…

Computation and Language · Computer Science 2025-03-04 Hui Ma , Bo Zhang , Bo Xu , Jian Wang , Hongfei Lin , Xiao Sun

Drug-target interaction (DTI) prediction has become a foundational task in drug repositioning, polypharmacology, drug discovery, as well as drug resistance and side-effect prediction. DTI identification using machine learning is gaining…

Quantitative Methods · Quantitative Biology 2023-11-17 Konstantin Y. Kalitin , Alexey A. Nevzorov , Denis A. Babkov , Alexander A. Spasov , Olga Y. Mukha

Recently, reinforcement learning has been used to address logic synthesis by formulating the operator sequence optimization problem as a Markov decision process. However, through extensive experiments, we find out that the learned policy…

Machine Learning · Computer Science 2022-06-28 Chao Wang , Chen Chen , Dong Li , Bin Wang

Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…

In this work, we formulate the problem of estimating and selecting task-relevant temporal signal segments from a single EEG trial in the form of a Markov decision process and propose a novel reinforcement-learning mechanism that can be…

Signal Processing · Electrical Eng. & Systems 2020-07-02 Wonjun Ko , Eunjin Jeon , Heung-Il Suk