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Single-parameter persistent homology, a key tool in topological data analysis, has been widely applied to data problems along with statistical techniques that quantify the significance of the results. In contrast, statistical techniques for…

Algebraic Topology · Mathematics 2020-12-14 Matthew Wright , Xiaojun Zheng

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser

In this paper we present an approach to determine the smallest possible number of neurons in a layer of a neural network in such a way that the topology of the input space can be learned sufficiently well. We introduce a general procedure…

Machine Learning · Statistics 2026-03-24 Luciano Melodia , Richard Lenz

Persistent homology is a common technique in topological data analysis providing geometrical and topological information about the sample space. All this information, known as topological features, is summarized in persistence diagrams, and…

Methodology · Statistics 2022-04-05 Asael Fabian Martínez

Researchers in the field of connectomics are working to reconstruct a map of neural connections in the brain in order to understand at a fundamental level how the brain processes information. Constructing this wiring diagram is done by…

Topological data analysis can reveal higher-order structure beyond pairwise connections between vertices in complex networks. We present a new method based on discrete Morse theory to study topological properties of unweighted and…

Discrete Mathematics · Computer Science 2019-10-01 Harish Kannan , Emil Saucan , Indrava Roy , Areejit Samal

In this article, we introduce a Topological Data Analysis (TDA) pipeline for neural spike train data. Understanding how the brain transforms sensory information into perception and behavior requires analyzing coordinated neural population…

Methodology · Statistics 2025-12-10 Cagatay Ayhan , Audrey N. Nash , Roberto Vincis , Martin Bauer , Richard Bertram , Tom Needham

The human brain has a complex, intricate functional architecture. While many studies primarily emphasize pairwise interactions, delving into high-order associations is crucial for a comprehensive understanding of how functional brain…

Neurons and Cognition · Quantitative Biology 2023-10-30 Qiang Li , Vince D. Calhoun , Adithya Ram Ballem , Shujian Yu , Jesus Malo , Armin Iraji

One of the primary areas of interest in applied algebraic topology is persistent homology, and, more specifically, the persistence diagram. Persistence diagrams have also become objects of interest in topological data analysis. However,…

Methodology · Statistics 2018-04-06 Eric Berry , Yen-Chi Chen , Jessi Cisewski-Kehe , Brittany Terese Fasy

Persistent homology computes the multiscale topology of a data set by using a sequence of discrete complexes. In this paper, we propose that persistent homology may be a useful tool for studying the structure of the landscape of string…

High Energy Physics - Theory · Physics 2019-04-24 Alex Cole , Gary Shiu

Topological data analysis is an emerging mathematical concept for characterizing shapes in multi-scale data. In this field, persistence diagrams are widely used as a descriptor of the input data, and can distinguish robust and noisy…

Machine Learning · Statistics 2017-06-13 Genki Kusano , Kenji Fukumizu , Yasuaki Hiraoka

Topology and machine learning are two actively researched topics not only in condensed matter physics, but also in data science. Here, we propose the use of topological data analysis in unsupervised learning of the topological phase…

Mesoscale and Nanoscale Physics · Physics 2022-05-12 Sungjoon Park , Yoonseok Hwang , Bohm-Jung Yang

Childhood maltreatment may adversely affect brain development and consequently influence behavioral, emotional, and psychological patterns during adulthood. In this study, we propose an analytical pipeline for modeling the altered…

Neurons and Cognition · Quantitative Biology 2023-11-16 Moo K. Chung , Tahmineh Azizi , Jamie L. Hanson , Andrew L. Alexander , Richard J. Davidson , Seth D. Pollak

There has been increasing interests in learning resting-state brain functional connectivity of autism disorders using functional magnetic resonance imaging (fMRI) data. The data in a standard brain template consist of over 200,000 voxel…

Methodology · Statistics 2016-03-22 Jichun Xie , Jian Kang

The effectiveness of Spatio-temporal Graph Neural Networks (STGNNs) in time-series applications is often limited by their dependence on fixed, hand-crafted input graph structures. Motivated by insights from the Topological Data Analysis…

Machine Learning · Computer Science 2025-03-20 Viet The Nguyen , Duy Anh Pham , An Thai Le , Jans Peter , Gunther Gust

Topological features such as persistence diagrams and their functional approximations like persistence images (PIs) have been showing substantial promise for machine learning and computer vision applications. This is greatly attributed to…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Anirudh Som , Hongjun Choi , Karthikeyan Natesan Ramamurthy , Matthew Buman , Pavan Turaga

Finding an optimal parameter of a black-box function is important for searching stable material structures and finding optimal neural network structures, and Bayesian optimization algorithms are widely used for the purpose. However, most of…

Machine Learning · Computer Science 2019-02-27 Tatsuya Shiraishi , Tam Le , Hisashi Kashima , Makoto Yamada

Phase separation mechanisms can produce a variety of complicated and intricate microstructures, which often can be difficult to characterize in a quantitative way. In recent years, a number of novel topological metrics for microstructures…

Numerical Analysis · Mathematics 2020-05-29 Paweł Dłotko , Thomas Wanner

Most humans have the good fortune to live their lives embedded in richly structured social groups. Yet, it remains unclear how humans acquire knowledge about these social structures to successfully navigate social relationships. Here we…

Neurons and Cognition · Quantitative Biology 2019-04-23 Steven H. Tompson , Ari E. Kahn , Emily B. Falk , Jean M. Vettel , Danielle S. Bassett

This paper concerns a theoretical approach that combines topological data analysis (TDA) and sheaf theory. Topological data analysis, a rising field in mathematics and computer science, concerns the shape of the data and has been proven…

Computer Vision and Pattern Recognition · Computer Science 2020-12-04 Chuan-Shen Hu , Yu-Min Chung