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Researchers often misinterpret and misrepresent statistical outputs. This abuse has led to a large literature on modification or replacement of testing thresholds and $P$-values with confidence intervals, Bayes factors, and other devices.…

Methodology · Statistics 2020-10-02 Zad Rafi , Sander Greenland

The cell biology literature is littered with erroneously tiny P values, often the result of evaluating individual cells as independent samples. Because readers use P values and error bars to infer whether a reported difference would likely…

Other Quantitative Biology · Quantitative Biology 2020-04-30 Samuel J. Lord , Katrina B. Velle , R. Dyche Mullins , Lillian K. Fritz-Laylin

Bayes factors represent the ratio of probabilities assigned to data by competing scientific hypotheses. Drawbacks of Bayes factors are their dependence on prior specifications that define null and alternative hypotheses and difficulties…

Statistics Theory · Mathematics 2023-03-29 Valen E. Johnson , Sandipan Pramanik , Rachael Shudde

The influential claim that most published results are false raised concerns about the trustworthiness and integrity of science. Since then, there have been numerous attempts to examine the rate of false-positive results that have failed to…

Applications · Statistics 2023-09-19 Ulrich Schimmack , František Bartoš

Which type of statistical uncertainty -- statistical (in)significance with a p-value, or a Bayesian probability -- enables people to see the continuous nature of uncertainty more clearly in a policymaking context? An original survey…

Other Statistics · Statistics 2024-02-20 Akisato Suzuki

This article gives a conceptual review of the e-value, ev(H|X) -- the epistemic value of hypothesis H given observations X. This statistical significance measure was developed in order to allow logically coherent and consistent tests of…

A pervasive issue in statistical hypothesis testing is that the reported $p$-values are biased downward by data "peeking" -- the practice of reporting only progressively extreme values of the test statistic as more data samples are…

Statistics Theory · Mathematics 2020-11-04 Akshay Balsubramani

Significance tests are probably the most extended form of inference in empirical research, and significance is often interpreted as providing greater informational content than non-significance. In this article we show, however, that…

Other Statistics · Statistics 2018-03-05 Alberto Abadie

The e-value is swiftly rising in prominence in many applications of hypothesis testing and multiple testing, yet its relationship to classical testing theory remains elusive. We unify e-values and classical testing into a single 'continuous…

Statistics Theory · Mathematics 2025-05-12 Nick W. Koning

Bayes Factors, the Bayesian tool for hypothesis testing, are receiving increasing attention in the literature. Compared to their frequentist rivals ($p$-values or test statistics), Bayes Factors have the conceptual advantage of providing…

Methodology · Statistics 2026-01-21 Stavros Nikolakopoulos , Björn Alfons Edmar , Ioannis Ntzoufras

A key objective in conducting a Bell test is to quantify the statistical evidence against a local-hidden variable model (LHVM) given that we can collect only a finite number of trials in any experiment. The notion of statistical evidence is…

Quantum Physics · Physics 2018-04-19 David Elkouss , Stephanie Wehner

We examine the role of trustworthiness and trust in statistical inference, arguing that it is the extent of trustworthiness in inferential statistical tools which enables trust in the conclusions. Certain tools, such as the p-value and…

Methodology · Statistics 2021-05-11 David J. Hand

Testing differences between a treatment and control group is common practice in biomedical research like randomized controlled trials (RCT). The standard two-sample t-test relies on null hypothesis significance testing (NHST) via p-values,…

Methodology · Statistics 2020-05-18 Riko Kelter

The Bayes factor, the data-based updating factor of the prior to posterior odds of two hypotheses, is a natural measure of statistical evidence for one hypothesis over the other. We show how Bayes factors can also be used for parameter…

Methodology · Statistics 2025-07-09 Samuel Pawel

The power of multiple testing procedures can be increased by using weighted p-values (Genovese, Roeder and Wasserman 2005). We derive the optimal weights and we show that the power is remarkably robust to misspecification of these weights.…

Statistics Theory · Mathematics 2007-06-13 Larry Wasserman , Kathryn Roeder

In this paper, we demonstrate that a new measure of evidence we developed called the Dempster-Shafer p-value which allow for insights and interpretations which retain most of the structure of the p-value while covering for some of the…

Methodology · Statistics 2024-02-28 Kentaro Hoffman , Kai Zhang , Tyler McCormick , Jan Hannig

A definition for the statistical significance by constructing a correlation between the normal distribution integral probability and the p-value observed in an experiment is proposed, which is suitable for both counting experiment and…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Yongsheng Zhu

The null hypothesis test (NHT) is widely used for validating scientific hypotheses but is actually highly criticized. Although Bayesian tests overcome several criticisms, some limits remain. We propose a Bayesian two-interval test (2IT) in…

Methodology · Statistics 2021-07-06 Nicolas Meyer , Erik-André Sauleau

We explain the concept of p-values presupposing only rudimentary probability theory. We also use the occasion to introduce the notion of p-function, so that p-values are values of a p-function. The explanation is restricted to the discrete…

Statistics Theory · Mathematics 2016-03-15 Yuri Gurevich , Vladimir Vovk

Meta-analysis combines results from multiple studies aiming to increase power in finding their common effect. It would typically reject the null hypothesis of no effect if any one of the studies shows strong significance. The partial…

Statistics Theory · Mathematics 2016-12-20 Jingshu Wang , Art B. Owen