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Uncertainty quantification is essential when dealing with ill-conditioned inverse problems due to the inherent nonuniqueness of the solution. Bayesian approaches allow us to determine how likely an estimation of the unknown parameters is…

Machine Learning · Statistics 2020-01-16 Ali Siahkoohi , Gabrio Rizzuti , Felix J. Herrmann

This study examines the application of Bayesian approach in the context of clinical trials, emphasizing their increasing importance in contemporary biomedical research. While conventional frequentist approach provides a foundational basis…

Methodology · Statistics 2026-01-16 Paramahansa Pramanik , Arnab Kumar Maity , Anjan Mandal , Haley Kate Robinson

We propose a Bayesian inference framework to estimate uncertainties in inverse scattering problems. Given the observed data, the forward model and their uncertainties, we find the posterior distribution over a finite parameter field…

Numerical Analysis · Mathematics 2020-11-17 Ana Carpio , Sergei Iakunin , Georg Stadler

High-contrast imaging for the detection and characterization of exoplanets relies on the instrument's capability to block out the light of the host star. Some current post-processing methods for calibrating out the residual speckles use…

Instrumentation and Methods for Astrophysics · Physics 2015-06-15 Marie Ygouf , Laurent M. Mugnier , David Mouillet , Thierry Fusco , Jean-Luc Beuzit

One of the big challenges in exoplanet science is to determine the atmospheric makeup of extrasolar planets, and to find biosignatures that hint at the existence of biochemical processes on another world. The biomarkers we are trying to…

Earth and Planetary Astrophysics · Physics 2025-01-23 Zixin Huang , Christian Schwab , Cosmo Lupo

Estimating the marginal likelihoods is an essential feature of model selection in the Bayesian context. It is especially crucial to have good estimates when assessing the number of planets orbiting stars when the models explain the noisy…

Earth and Planetary Astrophysics · Physics 2015-06-03 Mikko Tuomi , Hugh R. A. Jones

A new methodology for model determination in decomposable graphical Gaussian models is developed. The Bayesian paradigm is used and, for each given graph, a hyper inverse Wishart prior distribution on the covariance matrix is considered.…

Computation · Statistics 2015-03-13 Sophie Donnet , Jean-Michel Marin

The detection of exoplanets through direct imaging has produced numerous new positive identifications in recent years. The technique is biased towards planets at wide separations due to the difficulty in removing the stellar signature at…

Earth and Planetary Astrophysics · Physics 2015-06-12 Stephen R. Kane

Following the discovery of the brightest high-energy neutrino sources in the sky, the further detection of fainter sources is more challenging. A natural solution is to combine fainter source candidates, and instead of individual…

High Energy Astrophysical Phenomena · Physics 2025-06-03 I. Bartos , M. Ackermann , M. Kowalski

We propose a general method to carry out a valid Bayesian analysis of a finite-dimensional `targeted' parameter in the presence of a finite-dimensional nuisance parameter. We apply our methods to causal inference based on estimating…

Methodology · Statistics 2026-02-03 Magid Sabbagh , David A. Stephens

High throughput screening of compounds (chemicals) is an essential part of drug discovery [7], involving thousands to millions of compounds, with the purpose of identifying candidate hits. Most statistical tools, including the industry…

Machine Learning · Statistics 2017-09-29 Ivo D. Shterev , David B. Dunson , Cliburn Chan , Gregory D. Sempowski

Direct imaging of exoplanets is a challenging task due to the small angular distance and high contrast relative to their host star, and the presence of quasi-static noise. We propose a new statistical method for direct imaging of exoplanets…

Instrumentation and Methods for Astrophysics · Physics 2022-10-20 Hazan Daglayan , Simon Vary , Faustine Cantalloube , P. -A. Absil , Olivier Absil

The following zero-sum game between nature and a statistician blends Bayesian methods with frequentist methods such as p-values and confidence intervals. Nature chooses a posterior distribution consistent with a set of possible priors. At…

Methodology · Statistics 2011-07-19 David R. Bickel

The parametric bootstrap can be used for the efficient computation of Bayes posterior distributions. Importance sampling formulas take on an easy form relating to the deviance in exponential families and are particularly simple starting…

Applications · Statistics 2013-01-15 Bradley Efron

We consider the so-called unfolding problem in experimental high energy physics, where the goal is to estimate the true spectrum of elementary particles given observations distorted by measurement error due to the limited resolution of a…

Applications · Statistics 2014-02-03 Mikael Kuusela , Victor M. Panaretos

Modern imaging techniques heavily rely on Bayesian statistical models to address difficult image reconstruction and restoration tasks. This paper addresses the objective evaluation of such models in settings where ground truth is…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Tom Sprunck , Marcelo Pereyra , Tobias Liaudat

Joint detection and estimation refers to deciding between two or more hypotheses and, depending on the test outcome, simultaneously estimating the unknown parameters of the underlying distribution. This problem is investigated in a…

Signal Processing · Electrical Eng. & Systems 2019-04-19 Dominik Reinhard , Michael Fauss , Abdelhak M. Zoubir

Undirected graphical models are widely used in statistics, physics and machine vision. However Bayesian parameter estimation for undirected models is extremely challenging, since evaluation of the posterior typically involves the…

Computation · Statistics 2012-03-19 Richard G. Everitt

Bayesian model selection provides a formal method of determining the level of support for new parameters in a model. However, if there is not a specific enough underlying physical motivation for the new parameters it can be hard to assign…

Astrophysics · Physics 2009-11-13 Christopher Gordon , Roberto Trotta

Classically, Bayesian clustering interprets each component of a mixture model as a cluster. The inferred clustering posterior is highly sensitive to any inaccuracies in the kernel within each component. As this kernel is made more flexible,…

Methodology · Statistics 2025-12-12 David Buch , Miheer Dewaskar , David B. Dunson