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Cloud computing provides a great opportunity for scientists, as it enables large-scale experiments that cannot are too long to run on local desktop machines. Cloud-based computations can be highly parallel, long running and data-intensive,…

Software Engineering · Computer Science 2016-12-07 Maria Spichkova , Heinz W. Schmidt , Ian E. Thomas , Iman I. Yusuf , Steve Androulakis , Grischa R. Meyer

One of the more complex tasks for researchers using HPC systems is performance monitoring and tuning of their applications. Developing a practice of continuous performance improvement, both for speed-up and efficient use of resources is…

Modern data science research can involve massive computational experimentation; an ambitious PhD in computational fields may do experiments consuming several million CPU hours. Traditional computing practices, in which researchers use…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-28 Hatef Monajemi , Riccardo Murri , Eric Jonas , Percy Liang , Victoria Stodden , David L. Donoho

Serverless computing is gaining traction as an attractive model for the deployment of a multitude of workloads in the cloud. Designing and building effective resource management solutions for any computing environment requires extensive…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-20 Anupama Mampage , Rajkumar Buyya

We present Clinica (www.clinica.run), an open-source software platform designed to make clinical neuroscience studies easier and more reproducible. Clinica aims for researchers to i) spend less time on data management and processing, ii)…

Cloud computing offers on-demand, scalable computing and storage, and has become an essential resource for the analyses of big biomedical data. The usual approach to cloud computing requires users to reserve and provision virtual servers.…

Quantitative Methods · Quantitative Biology 2018-08-01 Dimitar Kumanov , Ling-Hong Hung , Wes Lloyd , Ka Yee Yeung

Automating the theory-experiment cycle requires effective distributed workflows that utilize a computing continuum spanning lab instruments, edge sensors, computing resources at multiple facilities, data sets distributed across multiple…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-22 Nathan Tallent , Jan Strube , Luanzheng Guo , Hyungro Lee , Jesun Firoz , Sayan Ghosh , Bo Fang , Oceane Bel , Steven Spurgeon , Sarah Akers , Christina Doty , Erol Cromwell

The application of high-performance computing (HPC) processes, tools, and technologies to Controlled Unclassified Information (CUI) creates both opportunities and challenges. Building on our experiences developing, deploying, and managing…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-10 Carolyn Ellis , Matthew Route , Christopher Phillips , Nicholas Smith , Alex Younts

Neuroscience research has evolved to generate increasingly large and complex experimental data sets, and advanced data science tools are taking on central roles in neuroscience research. Neurodata Without Borders (NWB), a standard language…

Neurons and Cognition · Quantitative Biology 2024-01-23 Andrea Pierré , Tuan Pham , Jonah Pearl , Sandeep Robert Datta , Jason T. Ritt , Alexander Fleischmann

Deep learning has been postulated as a solution for numerous problems in different branches of science. Given the resource-intensive nature of these models, they often need to be executed on specialized hardware such graphical processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-15 Jose González-Abad , Álvaro López García , Valentin Y. Kozlov

The increasing number of edge devices with enhanced sensing capabilities, such as smartphones, wearables, and IoT devices equipped with sensors, holds the potential for innovative smart-edge applications in healthcare. These devices…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-29 Patrick Langer , Elgar Fleisch , Filipe Barata

A key hurdle is demonstrating compute resource capability with limited benchmarks. We propose workflow templates as a solution, offering adaptable designs for specific scientific applications. Our paper identifies common usage patterns for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-31 Gregor von Laszewski , Wesley Brewer , Sean R. Wilkinson , Andrew Shao , J. P. Fleischer , Harshad Pitkar , Christine R. Kirkpatrick , Geoffrey C. Fox

Cloud platforms allow users to execute tasks directly from their web browser and are a key enabling technology not only for commerce but also for computational science. Research software is often developed by scientists with limited…

In recent years, deep learning revolutionized machine learning and its applications, producing results comparable to human experts in several domains, including neuroscience. Each year, hundreds of scientific publications present…

Quantitative Methods · Quantitative Biology 2023-01-13 Louis Fabrice Tshimanga , Manfredo Atzori , Federico Del Pup , Maurizio Corbetta

High performance computing (HPC) and cloud have traditionally been separate, and presented in an adversarial light. The conflict arises from disparate beginnings that led to two drastically different cultures, incentive structures, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-24 Vanessa Sochat , David Fox , Daniel Milroy

Effectively leveraging the vast computational resources of modern cloud environments requires expertise spanning multiple technical domains: configuring scientific software with correct parameters and dependencies, navigating thousands of…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-24 Shihan Cheng , Michael A. Laurenzano , Brian Strauch , Timothy A. Ellis , Krish Wadhwani , David A. B. Hyde

Software and hardware co-design and optimization of HPC systems has become intolerably complex, ad-hoc, time consuming and error prone due to enormous number of available design and optimization choices, complex interactions between all…

Software Engineering · Computer Science 2013-08-13 Grigori Fursin

Many attempts have been done to extend the great success of convolutional neural networks (CNNs) achieved on high-end GPU servers to portable devices such as smart phones. Providing compression and acceleration service of deep learning…

Machine Learning · Computer Science 2019-10-09 Yixing Xu , Yunhe Wang , Hanting Chen , Kai Han , Chunjing Xu , Dacheng Tao , Chang Xu

We present PolicyCLOUD, a prototype for an extensible, serverless cloud-based system that supports evidence-based elaboration and analysis of policies. PolicyCLOUD allows flexible exploitation and management of policy-relevant dataflows by…

The Large Hadron Collider (LHC) at CERN has generated in the last decade an unprecedented volume of data for the High-Energy Physics (HEP) field. Scientific collaborations interested in analysing such data very often require computing power…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-03 Jacek Kuśnierz , Vincenzo Eduardo Padulano , Maciej Malawski , Kamil Burkiewicz , Enric Tejedor Saavedra , Pedro Alonso-Jordá , Michael Pitt , Valentina Avati
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