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On the time scales accessible to atomistic numerical modelling, chemical reactions are considered rare events. Atomistic simulations are typically biased along a low-dimensional representation of a chemical reaction in an atomic structure…

Chemical Physics · Physics 2022-03-16 Martin Šípka , Andreas Erlebach , Lukáš Grajciar

Predicting future frames for a video sequence is a challenging generative modeling task. Promising approaches include probabilistic latent variable models such as the Variational Auto-Encoder. While VAEs can handle uncertainty and model…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Lluis Castrejon , Nicolas Ballas , Aaron Courville

Recent advances in artificial intelligence have propelled the development of innovative computational materials modeling and design techniques. Generative deep learning models have been used for molecular representation, discovery, and…

Chemical Physics · Physics 2021-02-12 Navid Shervani-Tabar , Nicholas Zabaras

The data drawn from biological, economic, and social systems are often confounded due to the presence of unmeasured variables. Prior work in causal discovery has focused on discrete search procedures for selecting acyclic directed mixed…

Machine Learning · Computer Science 2021-02-26 Rohit Bhattacharya , Tushar Nagarajan , Daniel Malinsky , Ilya Shpitser

Cross-validation (CV) is a widely-used method of predictive assessment based on repeated model fits to different subsets of the available data. CV is applicable in a wide range of statistical settings. However, in cases where data are not…

Methodology · Statistics 2025-04-23 Alex Cooper , Aki Vehtari , Catherine Forbes

Conditional variational autoencoders (CVAEs) are versatile deep generative models that extend the standard VAE framework by conditioning the generative model with auxiliary covariates. The original CVAE model assumes that the data samples…

Machine Learning · Statistics 2022-03-03 Siddharth Ramchandran , Gleb Tikhonov , Otto Lönnroth , Pekka Tiikkainen , Harri Lähdesmäki

Variational Autoencoders (VAEs) are expressive latent variable models that can be used to learn complex probability distributions from training data. However, the quality of the resulting model crucially relies on the expressiveness of the…

Machine Learning · Computer Science 2018-06-12 Lars Mescheder , Sebastian Nowozin , Andreas Geiger

Current causal discovery approaches require restrictive model assumptions in the absence of interventional data to ensure structure identifiability. These assumptions often do not hold in real-world applications leading to a loss of…

Machine Learning · Statistics 2025-06-25 Anish Dhir , Ruby Sedgwick , Avinash Kori , Ben Glocker , Mark van der Wilk

High-dimensional complex systems can be studied through multivariate analysis, as Principal Component Analysis, however large samples of observations frequently are needed for it. Here it is examined a method for small samples based on…

Applications · Statistics 2017-06-16 Dimitri Marques Abramov

Coordination recognition and subtle pattern prediction of future trajectories play a significant role when modeling interactive behaviors of multiple agents. Due to the essential property of uncertainty in the future evolution,…

Robotics · Computer Science 2019-05-03 Jiachen Li , Hengbo Ma , Wei Zhan , Masayoshi Tomizuka

Rare event sampling is a central problem in modern computational chemistry research. Among the existing methods, transition path sampling (TPS) can generate unbiased representations of reaction processes. However, its efficiency depends on…

Computational Physics · Physics 2024-04-04 Jintu Zhang , Odin Zhang , Luigi Bonati , TingJun Hou

Latent class analysis is used to perform model based clustering for multivariate categorical responses. Selection of the variables most relevant for clustering is an important task which can affect the quality of clustering considerably.…

Computation · Statistics 2016-06-17 Arthur White , Jason Wyse , Thomas Brendan Murphy

Simulating rare events, such as the transformation of a reactant into a product in a chemical reaction typically requires enhanced sampling techniques that rely on heuristically chosen collective variables (CVs). We propose using…

The CVAE is one of the most widely-used models in trajectory prediction for AD. It captures the interplay between a driving context and its ground-truth future into a probabilistic latent space and uses it to produce predictions. In this…

Bayesian cross-validation (CV) is a popular method for predictive model assessment that is simple to implement and broadly applicable. A wide range of CV schemes is available for time series applications, including generic leave-one-out…

Methodology · Statistics 2023-10-12 Alex Cooper , Dan Simpson , Lauren Kennedy , Catherine Forbes , Aki Vehtari

Hierarchical learning models, such as mixture models and Bayesian networks, are widely employed for unsupervised learning tasks, such as clustering analysis. They consist of observable and hidden variables, which represent the given data…

Machine Learning · Statistics 2018-01-08 Keisuke Yamazaki

Predicting drop coalescence based on process parameters is crucial for experiment design in chemical engineering. However, predictive models can suffer from the lack of training data and more importantly, the label imbalance problem. In…

Computational Engineering, Finance, and Science · Computer Science 2023-05-02 Kewei Zhu , Sibo Cheng , Nina Kovalchuk , Mark Simmons , Yi-Ke Guo , Omar K. Matar , Rossella Arcucci

The data-based discovery of effective, coarse-grained (CG) models of high-dimensional dynamical systems presents a unique challenge in computational physics and particularly in the context of multiscale problems. The present paper offers a…

Computational Physics · Physics 2021-02-10 Sebastian Kaltenbach , Phaedon-Stelios Koutsourelakis

Variational Auto-Encoders (VAEs) are capable of learning latent representations for high dimensional data. However, due to the i.i.d. assumption, VAEs only optimize the singleton variational distributions and fail to account for the…

Machine Learning · Computer Science 2020-04-20 Da Tang , Dawen Liang , Tony Jebara , Nicholas Ruozzi

In many real world problems, features do not act alone but in combination with each other. For example, in genomics, diseases might not be caused by any single mutation but require the presence of multiple mutations. Prior work on feature…

Machine Learning · Computer Science 2023-01-12 Fergus Imrie , Alexander Norcliffe , Pietro Lio , Mihaela van der Schaar