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Affected relatives are essential for pedigree linkage analysis, however, they cause a violation of the independent sample assumption in case-control association studies. To avoid the correlation between samples, a common practice is to take…

Quantitative Methods · Quantitative Biology 2011-05-03 Yaning Yang , Elaine F. Remmers , Chukwuma B. Ogunwole , Daniel L. Kastner , Peter K. Gregersen , Wentian Li

The idea that there are any large-scale trends in the evolution of biological organisms is highly controversial. It is commonly believed, for example, that there is a large-scale trend in evolution towards increasing complexity, but…

Neural and Evolutionary Computing · Computer Science 2021-06-08 Peter D. Turney

We consider a random model of diffusion and coagulation. A large number of small particles are randomly scattered at an initial time. Each particle has some integer mass and moves in a Brownian motion whose diffusion rate is determined by…

Probability · Mathematics 2012-08-21 Alan Hammond , Fraydoun Rezakhanlou

A strong demographic Allee effect in which the expected population growth rate is negative below a certain critical population size can cause high extinction probabilities in small introduced populations. However, many species are…

Populations and Evolution · Quantitative Biology 2013-11-22 Meike J. Wittmann , Wilfried Gabriel , Dirk Metzler

An evolution equation for a population of strings evolving under the genetic operators: selection, mutation and crossover is derived. The corresponding equation describing the evolution of schematas is found by performing an exact coarse…

adap-org · Physics 2008-02-03 C. R. Stephens , H. Waelbroeck

We show that the stationary density fluctuations of exclusion processes with long jumps, whose rates are of the form $c^\pm |y-x|^{-(1+\alpha)}$ where $c\pm$ depends on the sign of $y-x$, are given by a fractional Ornstein-Uhlenbeck process…

Probability · Mathematics 2017-09-05 Patrícia Gonçalves , Milton Jara

Phylogenetic analyses of gene expression have great potential for addressing a wide range of questions. These analyses will, for example, identify genes that have evolutionary shifts in expression that are correlated with evolutionary…

Populations and Evolution · Quantitative Biology 2014-01-14 Casey W. Dunn , Xi Luo , Zhijin Wu

In models for the evolution of predation from initially purely competitive species interactions, the propensity of predation is most often assumed to be a direct consequence of the relative morphological and physiological traits of…

Populations and Evolution · Quantitative Biology 2023-07-11 Yaroslav Ispolatov , Carlos Doebeli , Michael Doebeli

Discovering evolutionary traits that are heritable across species on the tree of life (also referred to as a phylogenetic tree) is of great interest to biologists to understand how organisms diversify and evolve. However, the measurement of…

We are interested in the evolving genealogy of a birth and death process with trait structure and ecological interactions. Traits are hereditarily transmitted from a parent to its offspring unless a mutation occurs. The dynamics may depend…

Probability · Mathematics 2012-06-20 Sylvie Méléard , Viet Chi Tran

We study a density-dependent Markov jump process describing a population where each individual is characterized by a type, and reproduces at rates depending both on its type and on the population type distribution. We are interested in the…

Probability · Mathematics 2026-02-26 Madeleine Kubasch

Adaptive importance sampling techniques are widely known for the Gaussian setting of Brownian driven diffusions. In this work, we want to extend them to jump processes. Our approach relies on a change of the jump intensity combined with the…

Probability · Mathematics 2013-07-09 Laetitia Badouraly Kassim , Jérôme Lelong , Imane Loumrhari

In their well-known textbook (Vincent & Brown, 2005), Vincent and Brown suggested an attractive approach for studying evolutionary dynamics of populations that are heterogeneous with respect to some strategy that affects the fitness of…

Populations and Evolution · Quantitative Biology 2023-02-23 Georgiy Karev

We derive the asymptotic behaviour of the genealogy of a logistic branching process in the setting where the equilibrium population size is large. In three regimes on the tail of the offspring distribution we recover the Kingman,…

Probability · Mathematics 2025-11-11 Ruairi Garrett , Julio Ernesto Nava Trejo

Given an ideal J on a smooth variety in characteristic zero, we estimate the F-jumping numbers of the reductions of J to positive characteristic in terms of the jumping numbers of J and the characteristic. We apply one of our estimates to…

Commutative Algebra · Mathematics 2015-01-14 Mircea Mustata , Wenliang Zhang

We consider a general class of Markovian models describing the growth in a randomly fluctuating environment of a clonal biological population having several phenotypes related by stochastic switching. Phenotypes differ e.g. by the level of…

Populations and Evolution · Quantitative Biology 2022-01-25 J. Unterberger

The Central Limit Theorem provides a foundation for inferential statistics and hypothesis testing. It describes how standardized statistics behave under repeated sampling from large populations. However, if the size of the sample (n)…

Methodology · Statistics 2026-05-19 Mike Crowhurst

We study a universal object for the genealogy of a sample in populations with mutations: the critical birth-death process with Poissonian mutations, conditioned on its population size at a fixed time horizon. We show how this process arises…

Probability · Mathematics 2014-07-30 G. Achaz , C. Delaporte , A. Lambert

The reduction of the number of samples is a key issue in signal processing for mobile applications. We investigate the link between the smoothness properties of a signal and the number of samples that can be obtained through a level…

Functional Analysis · Mathematics 2014-12-30 Brigitte Bidégaray-Fesquet , Marianne Clausel

1. Abrupt environmental changes can lead to evolutionary shifts in trait evolution. Identifying these shifts is an important step in understanding the evolutionary history of phenotypes. 2. We propose an ensemble variable selection method…

Populations and Evolution · Quantitative Biology 2022-04-14 Wensha Zhang , Toby Kenney , Lam Si Tung Ho