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Unstructured information comprises a valuable source of data in clinical records. For text mining in clinical records, concept extraction is the first step in finding assertions and relationships. This study presents a system developed for…

Information Retrieval · Computer Science 2010-12-09 Ning Kang , Rogier Barendse , Zubair Afzal , Bharat Singh , Martijn J. Schuemie , Erik M. van Mulligen , Jan A. Kors

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

If Electronic Health Records contain a large amount of information about the patients condition and response to treatment, which can potentially revolutionize the clinical practice, such information is seldom considered due to the…

A significant amount of data held in Oncology Electronic Medical Records (EMRs) is contained in unstructured provider notes -- including but not limited to the chemotherapy (or cancer treatment) outcome, different biomarkers, the tumor's…

The digitalization of stored information in hospitals now allows for the exploitation of medical data in text format, as electronic health records (EHRs), initially gathered for other purposes than epidemiology. Manual search and analysis…

Electronic health records (EHR) contain large volumes of unstructured text, requiring the application of Information Extraction (IE) technologies to enable clinical analysis. We present the open-source Medical Concept Annotation Toolkit…

Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes. Despite their vital role, no current oncology…

Computation and Language · Computer Science 2024-03-18 Madhumita Sushil , Vanessa E. Kennedy , Divneet Mandair , Brenda Y. Miao , Travis Zack , Atul J. Butte

This paper describes an initial dataset and automatic natural language processing (NLP) method for extracting concepts related to precision oncology from biomedical research articles. We extract five concept types: Cancer, Mutation,…

Artificial Intelligence · Computer Science 2020-10-02 Nicholas Greenspan , Yuqi Si , Kirk Roberts

The integration of Large Language Models (LLMs) into biomedical research offers new opportunities for domainspecific reasoning and knowledge representation. However, their performance depends heavily on the semantic quality of training…

Natural Language Processing (NLP) is a key technique for developing Medical Artificial Intelligence (AI) systems that leverage Electronic Health Record (EHR) data to build diagnostic and prognostic models. NLP enables the conversion of…

Research projects, including those focused on cancer, rely on the manual extraction of information from clinical reports. This process is time-consuming and prone to errors, limiting the efficiency of data-driven approaches in healthcare.…

Computation and Language · Computer Science 2025-05-16 J. Moreno-Casanova , J. M. Auñón , A. Mártinez-Pérez , M. E. Pérez-Martínez , M. E. Gas-López

Medical information extraction consists of a group of natural language processing (NLP) tasks, which collaboratively convert clinical text to pre-defined structured formats. Current state-of-the-art (SOTA) NLP models are highly integrated…

Computation and Language · Computer Science 2022-03-09 Enwei Zhu , Qilin Sheng , Huanwan Yang , Jinpeng Li

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Objective: This review aims to analyze the application of natural language processing (NLP) techniques in cancer research using electronic health records (EHRs) and clinical notes. This review addresses gaps in the existing literature by…

Computation and Language · Computer Science 2025-02-05 Muhammad Bilal , Ameer Hamza , Nadia Malik

Precision medicine has the potential to revolutionize healthcare, but much of the data for patients is locked away in unstructured free-text, limiting research and delivery of effective personalized treatments. Generating large annotated…

Computation and Language · Computer Science 2020-12-16 Nick Altieri , Briton Park , Mara Olson , John DeNero , Anobel Odisho , Bin Yu

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Clinical notes contain unstructured representations of patient histories, including the relationships between medical problems and prescription drugs. To investigate the relationship between cancer drugs and their associated symptom burden,…

Computation and Language · Computer Science 2024-09-09 Yujuan Fu , Giridhar Kaushik Ramachandran , Ahmad Halwani , Bridget T. McInnes , Fei Xia , Kevin Lybarger , Meliha Yetisgen , Özlem Uzuner

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

The development of neural networks for clinical artificial intelligence (AI) is reliant on interpretability, transparency, and performance. The need to delve into the black-box neural network and derive interpretable explanations of model…

Computation and Language · Computer Science 2021-11-16 Niall Taylor , Lei Sha , Dan W Joyce , Thomas Lukasiewicz , Alejo Nevado-Holgado , Andrey Kormilitzin
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