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This paper develops a large-scale Bayesian spatio-temporal binomial regression model for the purpose of investigating regional trends in antibody prevalence to Borrelia burgdorferi, the causative agent of Lyme disease. The proposed model…

Borrelia burgdorferi sensu stricto is a bacterial spirochete prevalent in the Northeastern United States that causes Lyme disease. Lyme disease is the most common arthropod-borne disease in the United States; affecting mice, deer, humans…

Populations and Evolution · Quantitative Biology 2013-08-12 Matthew Jastrebski , Joan Ponce , Daniel Burkow , Oyita Udiani , Dr. Leon Arriola

Spatially varying coefficient (SVC) models are a type of regression model for spatial data where covariate effects vary over space. If there are several covariates, a natural question is which covariates have a spatially varying effect and…

Methodology · Statistics 2021-02-12 Jakob A. Dambon , Fabio Sigrist , Reinhard Furrer

Epidemiological investigations of regionally aggregated spatial data often involve detecting spatial health disparities among neighboring regions on a map of disease mortality or incidence rates. Analyzing such data introduces spatial…

Methodology · Statistics 2025-11-21 Kyle Lin Wu , Sudipto Banerjee

The advent of high-throughput sequencing technologies has made data from DNA material readily available, leading to a surge of microbiome-related research establishing links between markers of microbiome health and specific outcomes.…

Methodology · Statistics 2018-06-19 Susheela P. Singh , Ana-Maria Staicu , Robert R. Dunn , Noah Fierer , Brian J. Reich

The Cox regression model is a commonly used model in survival analysis. In public health studies, clinical data are often collected from medical service providers of different locations. There are large geographical variations in the…

Applications · Statistics 2021-07-30 Jinjian Mu , Qingyang Liu , Lynn Kuo , Guanyu Hu

We consider a problem of ecological inference, in which individual-level covariates are known, but labeled data is available only at the aggregate level. The intended application is modeling voter preferences in elections. In Rosenman and…

Machine Learning · Statistics 2019-07-23 Evan Rosenman

The COVID-19 pandemic provided many modeling challenges to investigate the evolution of an epidemic process over areal units. A suitable encompassing model must describe the spatio-temporal variations of the disease infection rate of…

Methodology · Statistics 2023-11-20 Pierfrancesco Alaimo Di Loro , Dankmar Boehning , Sujit Sahu

A major public health concern in the United States (US) is gun-related deaths. The number of gun injuries largely varies spatially because of county-wise heterogeneity of race, sex, age, and income distributions. But still, a major…

Methodology · Statistics 2026-01-28 Debjoy Thakur , Lingyuan Zhao , Soutir Bandyopadhyay

Lyme disease is a rapidly growing illness that remains poorly understood within the medical community. Critical questions about when and why patients respond to treatment or stay ill, what kinds of treatments are effective, and even how to…

Computers and Society · Computer Science 2020-09-22 Joshua Vendrow , Jamie Haddock , Deanna Needell , Lorraine Johnson

In this study, we propose an automatic learning method for variables selection based on Lasso in epidemiology context. One of the aim of this approach is to overcome the pretreatment of experts in medicine and epidemiology on collected…

Machine Learning · Statistics 2015-09-10 Bienvenue Kouwayè , Noël Fonton , Fabrice Rossi

Current risk mapping models for pooled data focus on the estimated risk for each geographical unit. A risk classification, that is, grouping of geographical units with similar risk, is then necessary to easily draw interpretable maps, with…

Applications · Statistics 2013-12-11 Florence Forbes , Myriam Charras-Garrido , Lamiae Azizi , Senan Doyle , David Abrial

To study the impact of climate variables on morbidity of some diseases in Mexico, we propose a spatio-temporal varying coefficients regression model. For that we introduce a new spatio-temporal dependent process prior, in a Bayesian…

Applications · Statistics 2019-12-02 Luis E. Nieto-Barajas

Lyme disease which is one of the most common infectious vector-borne diseases manifests itself in most cases with erythema migrans (EM) skin lesions. Recent studies show that convolutional neural networks (CNNs) perform well to identify…

Spatio-temporal pathogen spread is often partially observed at the metapopulation scale. Available data correspond to proxies and are incomplete, censored and heterogeneous. Moreover, representing such biological systems often leads to…

Populations and Evolution · Quantitative Biology 2023-12-04 Gaël Beaunée , Pauline Ezanno , Alain Joly , Pierre Nicolas , Elisabeta Vergu

High-dimensional spatially correlated covariates are common in regression models encountered in environmental sciences and other fields. In such models, the regression coefficients often exhibit a sparse structure with spatial dependence.…

Methodology · Statistics 2026-05-08 Zihan Zhu , Xueying Tang , Shuang Zhou

Understanding the dynamics of infectious disease spread in a heterogeneous population is an important factor in designing control strategies. Here, we develop a novel tensor-driven multi-compartment version of the classic…

Populations and Evolution · Quantitative Biology 2020-04-22 Inbar Seroussi , Nir Levy , Elad Yom-Tov

We present a new modeling technique for solving the problem of ecological inference, in which individual-level associations are inferred from labeled data available only at the aggregate level. We model aggregate count data as arising from…

Machine Learning · Statistics 2018-02-06 Evan Rosenman , Nitin Viswanathan

Increasing rates of global trade and travel, as well as changing climatic patterns, have led to more frequent outbreaks of plant disease epidemics worldwide. Mathematical modelling is a key tool in predicting where and how these new threats…

Populations and Evolution · Quantitative Biology 2019-11-28 Frédéric Fabre , Jérôme Coville , Nik J. Cunniffe

Around the globe, ticks are the culprit of transmitting a variety of bacterial, viral and parasitic diseases. The incidence of tick-borne diseases has drastically increased within the last decade, with annual cases of Lyme disease soaring…

Image and Video Processing · Electrical Eng. & Systems 2020-11-24 Lauren Michelle Pfeifer , Matias Valdenegro-Toro
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