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Realizing high-throughput aberration-corrected Scanning Transmission Electron Microscopy (STEM) exploration of atomic structures requires rapid tuning of multipole probe correctors while compensating for the inevitable drift of the optical…

Machine Learning · Computer Science 2026-01-28 Utkarsh Pratiush , Austin Houston , Richard Liu , Gerd Duscher , Sergei Kalinin

Conventional beamforming with fixed-orientation antenna (FOA) arrays may struggle to effectively enhance signal and/or suppress interference due to significant variations in antenna directive gains over different steering angles. To break…

Information Theory · Computer Science 2025-10-23 Jie Feng , Zhenbing Liu , Junjie Dai , Hongbin Chen , Fangjiong Chen

Objective: Proton spot-scanning arc therapy (ARC) is an emerging modality that can improve the high-dose conformity to targets compared with standard intensity-modulated proton therapy (IMPT). However, the efficient treatment delivery of…

This paper focuses on optimal beamforming to maximize the mean signal-to-noise ratio (SNR) for a reconfigurable intelligent surface (RIS)-aided MISO downlink system under correlated Rician fading. The beamforming problem becomes non-convex…

Information Theory · Computer Science 2023-07-04 Kali Krishna Kota , M. S. S. Manasa , Praful D. Mankar , Harpreet S. Dhillon

Future intelligent indoor wireless environments require fast and reliable beam alignment to sustain high-throughput links under mobility and blockage. Exhaustive beam training achieves optimal performance but is prohibitively costly. In…

Networking and Internet Architecture · Computer Science 2026-02-19 Parth Ashokbhai Shiroya , Amod Ashtekar , Swarnagowri Shashidhar , Mohammed E. Eltayeb

Multi-objective Bayesian optimization (MOBO) provides a principled framework for optimizing expensive black-box functions with multiple objectives. However, existing MOBO methods often struggle with coverage, scalability with respect to the…

Machine Learning · Computer Science 2026-04-20 Yaohong Yang , Sammie Katt , Samuel Kaski

Fluence map optimization for intensity-modulated radiation therapy planning can be formulated as a large-scale inverse problem with competing objectives and constraints associated with the tumors and organs-at-risk. Unfortunately,…

Optimization and Control · Mathematics 2022-02-17 Kelsey Maass , Minsun Kim , Aleksandr Aravkin

In this letter, secure beamforming in a multiple intelligent reflecting surfaces (IRSs)-aided millimeter-wave (mmWave) system is investigated. In this system, the secrecy rate is maximized by controlling the on-off status of each IRS as…

Signal Processing · Electrical Eng. & Systems 2020-12-29 Yue Xiu , Jun Zhao , Chau Yuen , Zhongpei Zhang , Guan Gui

Optimizing objectives under constraints, where both the objectives and constraints are black box functions, is a common scenario in real-world applications such as scientific experimental design, design of medical therapies, and industrial…

Machine Learning · Computer Science 2023-10-16 Fengxue Zhang , Zejie Zhu , Yuxin Chen

Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…

Medical Physics · Physics 2023-12-05 Keshav Kumar K. , NVSL Narasimham , A. Ramakrishna Prasad

Direction-of-arrival (DOA) estimation is one of the most demanding tasks for the millimeter wave (mmWave) communication of massive multiple-input multiple-output (MIMO) systems with the hybrid beamforming (HBF) architecture. In this paper,…

Information Theory · Computer Science 2021-09-01 Tian Lin , Xuemeng Zhou , Yu Zhu , Yi Jiang

Multicriteria optimization problems occur in many real life applications, for example in cancer radiotherapy treatment and in particular in intensity modulated radiation therapy (IMRT). In this work we focus on optimization problems with…

Optimization and Control · Mathematics 2017-04-05 Esther Bonacker , Aviv Gibali , Karl-Heinz Küfer , and Philipp Süss

A framework for online robust adaptive radiation therapy (ART) is presented. This framework is designed to (i) handle interfractional geometric variations following a probability distribution different from the a priori hypothesis, (ii)…

Medical Physics · Physics 2020-09-09 Michelle Böck

Bayesian optimization (BO) is a sample-efficient approach for tuning design parameters to optimize expensive-to-evaluate, black-box performance metrics. In many manufacturing processes, the design parameters are subject to random input…

Machine Learning · Computer Science 2022-06-06 Samuel Daulton , Sait Cakmak , Maximilian Balandat , Michael A. Osborne , Enlu Zhou , Eytan Bakshy

We propose a novel constrained Bayesian Optimization (BO) algorithm optimizing the design process of Laterally-Diffused Metal-Oxide-Semiconductor (LDMOS) transistors while realizing a target Breakdown Voltage (BV). We convert the…

Machine Learning · Computer Science 2023-08-21 Ping-Ju Chuang , Ali Saadat , Sara Ghazvini , Hal Edwards , William G. Vandenberghe

Constrained convex optimization problems arise naturally in many real-world applications. One strategy to solve them in an approximate way is to translate them into a sequence of convex feasibility problems via the recently developed level…

Optimization and Control · Mathematics 2019-04-30 E. Bonacker , A. Gibali , K. -H. Küfer

Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose.…

This paper studies a multiple-input multiple-output (MIMO) radar system for sensing the unknown and random angular location (angle) of a point target, based on the target-reflected echo signals and known prior distribution information about…

Information Theory · Computer Science 2026-04-24 Yizhuo Wang , Shuowen Zhang

Directional transmission patterns (a.k.a. narrow beams) are the key to wireless communications in millimeter wave (mmWave) frequency bands which suffer from high path loss and severe shadowing. In addition, the propagation channel in mmWave…

Information Theory · Computer Science 2020-05-29 Abbas Khalili , Shahram Shahsavari , Mohammad A. Amir Khojastepour , Elza Erkip

The steep dose gradients obtained with pencil beam scanning allow for precise tumor targeting at the cost of high sensitivity to uncertainties. Robust optimization is commonly applied to mitigate uncertainties in density and patient setup,…

Medical Physics · Physics 2024-11-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson , Ye Zhang