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The ability to effectively control brain dynamics holds great promise for the enhancement of cognitive function in humans, and the betterment of their quality of life. Yet, successfully controlling dynamics in neural systems is challenging,…

Quantitative Methods · Quantitative Biology 2018-08-29 Evelyn Tang , Danielle S. Bassett

Mental disorders like major depressive disorder can be seen as complex dynamical systems. In this study we investigate the dynamic behaviour of individuals to see whether or not we can expect a transition to another mood state. We introduce…

Physics and Society · Physics 2019-03-27 Jolanda J Kossakowski , Marijke C M Gordijn , Harriette Riese , Lourens J Waldorp

It is essential to understand the complex structure of the human brain to develop new treatment approaches for neurodegenerative disorders (NDDs). This review paper comprehensively discusses the challenges associated with modelling the…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

A general dynamical process model of psychiatric disorders is proposed that specifies the basic cognitive processes involved in the transition from beliefs about self, others and world that are normal and adaptive, to beliefs that are…

Adaptation and Self-Organizing Systems · Physics 2013-09-24 Brian P. O'Connor , Liane Gabora

As the emerging field of predictive analytics in psychiatry generated and continues to generate massive interest overtime with its major promises to positively change and revolutionize clinical psychiatry, health care and medical…

Computers and Society · Computer Science 2019-05-30 Soaad Hossain

In this paper, we characterize major depression (MD) as a complex dynamical system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be…

This survey presents the most relevant neural network models of autism spectrum disorder and schizophrenia, from the first connectionist models to recent deep network architectures. We analyzed and compared the most representative symptoms…

Neurons and Cognition · Quantitative Biology 2019-11-22 Pablo Lanillos , Daniel Oliva , Anja Philippsen , Yuichi Yamashita , Yukie Nagai , Gordon Cheng

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

Neurons and Cognition · Quantitative Biology 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Precision medicine has received attention both in and outside the clinic. We focus on the latter, by exploiting the relationship between individuals' social interactions and their mental health to develop a predictive model of one's…

Social and Information Networks · Computer Science 2019-08-08 Shikang Liu , David Hachen , Omar Lizardo , Christian Poellabauer , Aaron Striegel , Tijana Milenkovic

Background: Mathematical modeling approaches are becoming ever more established in clinical neuroscience. They provide insight that is key to understand complex interactions of network phenomena, in general, and interactions within the…

Neurons and Cognition · Quantitative Biology 2014-04-25 Markus A. Dahlem , Jürgen Kurths , Michel D. Ferrari , Kazuyuki Aihara , Marten Scheffer , Arne May

Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…

Computational methods have complemented experimental and clinical neursciences and led to improvements in our understanding of the nervous systems in health and disease. In parallel, neuromodulation in form of electric and magnetic…

Neurons and Cognition · Quantitative Biology 2014-08-13 Markus A. Dahlem , Sebastian Rode , Arne May , Naoya Fujiwara , Yoshito Hirata , Kazuyuki Aihara , Jürgen Kurths

Individual and community psychology plays an important role in disaster management as human behavior exhibit diverse risk perceptions, recognition of the threats that exists, positive and negative emotions, panic, anger, rumor, stress and…

Physics and Society · Physics 2023-01-19 Liaquat Hossain

Background: A therapeutic intervention in psychiatry can be viewed as an attempt to influence the brain's large-scale, dynamic network state transitions underlying cognition and behavior. Building on connectome-based graph analysis and…

Network analyses in nervous system disorders involves constructing and analyzing anatomical and functional brain networks from neuroimaging data to describe and predict the clinical syndromes that result from neuropathology. A network view…

Neurons and Cognition · Quantitative Biology 2017-01-05 John D. Medaglia , Danielle S. Bassett

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

We consider neural networks from the point of view of dynamical systems theory. In this spirit we review recent results dealing with the following questions, adressed in the context of specific models. 1. Characterizing the collective…

Adaptation and Self-Organizing Systems · Physics 2010-11-09 B. Cessac

Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of…

Neurons and Cognition · Quantitative Biology 2014-08-26 Klaus Lehnertz , Gerrit Ansmann , Stephan Bialonski , Henning Dickten , Christian Geier , Stephan Porz

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

Machine Learning · Computer Science 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Recently, the potential of dynamic brain networks as a neuroimaging biomarkers for mental illnesses is being increasingly recognized. However, there are several unmet challenges in developing such biomarkers, including the need for methods…

Neurons and Cognition · Quantitative Biology 2019-10-10 Suprateek Kundu , Jin Ming , Jennifer Stevens
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