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We develop a learning framework for building deformable templates, which play a fundamental role in many image analysis and computational anatomy tasks. Conventional methods for template creation and image alignment to the template have…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Adrian V. Dalca , Marianne Rakic , John Guttag , Mert R. Sabuncu

Computer-aided medical image segmentation has been applied widely in diagnosis and treatment to obtain clinically useful information of shapes and volumes of target organs and tissues. In the past several years, convolutional neural network…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Yixuan Wu , Kuanlun Liao , Jintai Chen , Jinhong Wang , Danny Z. Chen , Honghao Gao , Jian Wu

Medical image registration drives quantitative analysis across organs, modalities, and patient populations. Recent deep learning methods often combine low-level "trend-driven" computational blocks from computer vision, such as large-kernel…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Bailiang Jian , Jiazhen Pan , Rohit Jena , Morteza Ghahremani , Hongwei Bran Li , Daniel Rueckert , Christian Wachinger , Benedikt Wiestler

Conventional approaches to image registration consist of time consuming iterative methods. Most current deep learning (DL) based registration methods extract deep features to use in an iterative setting. We propose an end-to-end DL method…

Computer Vision and Pattern Recognition · Computer Science 2019-09-11 Dwarikanath Mahapatra

Registration of brain MRI images requires to solve a deformation field, which is extremely difficult in aligning intricate brain tissues, e.g., subcortical nuclei, etc. Existing efforts resort to decomposing the target deformation field…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Jinxin Lv , Zhiwei Wang , Hongkuan Shi , Haobo Zhang , Sheng Wang , Yilang Wang , Qiang Li

In clinical practice, well-aligned multi-modal images, such as Magnetic Resonance (MR) and Computed Tomography (CT), together can provide complementary information for image-guided therapies. Multi-modal image registration is essential for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-29 Zekang Chen , Jia Wei , Rui Li

In the field of 3D medical imaging, accurately extracting and representing the blood vessels with curvilinear structures holds paramount importance for clinical diagnosis. Previous methods have commonly relied on discrete representation…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Ziwei Zhao , Zhixing Zhang , Yuhang Liu , Zhao Zhang , Haojun Yu , Dong Wang , Liwei Wang

In general, the problem of non-rigid registration is about matching two different scans of a dynamic object taken at two different points in time. These scans can undergo both rigid motions and non-rigid deformations. Since new parts of the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Alireza Ahmadi

In the last decade, convolutional neural networks (ConvNets) have been a major focus of research in medical image analysis. However, the performances of ConvNets may be limited by a lack of explicit consideration of the long-range spatial…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Junyu Chen , Eric C. Frey , Yufan He , William P. Segars , Ye Li , Yong Du

Deformable registration is crucial in medical imaging. Several existing applications include lesion tracking, probabilistic atlas generation, and treatment response evaluation. However, current methods often lack robustness and…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Yunzheng Zhu , Aichi Chien , Kimaya kulkarni , Luoting Zhuang , Stephen Park , Ricky Savjani , Daniel Low , William Hsu

The alignment of serial-section electron microscopy (ssEM) images is critical for efforts in neuroscience that seek to reconstruct neuronal circuits. However, each ssEM plane contains densely packed structures that vary from one section to…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Inwan Yoo , David G. C. Hildebrand , Willie F. Tobin , Wei-Chung Allen Lee , Won-Ki Jeong

Indirect image registration is a promising technique to improve image reconstruction quality by providing a shape prior for the reconstruction task. In this paper, we propose a novel hybrid method that seeks to reconstruct high quality…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Jiulong Liu , Angelica I. Aviles-Rivero , Hui Ji , Carola-Bibiane Schönlieb

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

In unsupervised medical image registration, the predominant approaches involve the utilization of a encoder-decoder network architecture, allowing for precise prediction of dense, full-resolution displacement fields from given paired…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Xi Jia , Wenqi Lu , Xinxing Cheng , Jinming Duan

Dynamic MRI enables a range of clinical applications, including cardiac function assessment, organ motion tracking, and radiotherapy guidance. However, fully sampling the dynamic k-space data is often infeasible due to time constraints and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 George Yiasemis , Jan-Jakob Sonke , Jonas Teuwen

One of the fundamental challenges in supervised learning for multimodal image registration is the lack of ground-truth for voxel-level spatial correspondence. This work describes a method to infer voxel-level transformation from…

In the last decade, convolutional neural networks (ConvNets) have dominated and achieved state-of-the-art performances in a variety of medical imaging applications. However, the performances of ConvNets are still limited by lacking the…

Image and Video Processing · Electrical Eng. & Systems 2021-04-15 Junyu Chen , Yufan He , Eric C. Frey , Ye Li , Yong Du

In this paper, we propose a novel medical image segmentation using iterative deep learning framework. We have combined an iterative learning approach and an encoder-decoder network to improve segmentation results, which enables to precisely…

Computer Vision and Pattern Recognition · Computer Science 2017-08-14 Jung Uk Kim , Hak Gu Kim , Yong Man Ro

In this paper, we propose a novel learning-based framework for 3D shape registration, which overcomes the challenges of significant non-rigid deformation and partiality undergoing among input shapes, and, remarkably, requires no…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Zhangquan Chen , Puhua Jiang , Mingze Sun , Ruqi Huang

Deformable image registration, i.e., the task of aligning multiple images into one coordinate system by non-linear transformation, serves as an essential preprocessing step for neuroimaging data. Recent research on deformable image…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Yao Su , Xin Dai , Lifang He , Xiangnan Kong