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Pencil beam scanning (PBS) proton therapy provides highly conformal dose distributions that are increasingly leveraged for postmastectomy radiation therapy (PMRT) to reduce cardiopulmonary exposure. However, implant-based reconstruction in…

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

We investigate the regularization-scheme dependent treatment of $\gamma_{5}$ in the framework of dimensional regularization, mainly focusing on the four-dimensional helicity scheme (FDH). Evaluating distinctive examples, we find that for…

High Energy Physics - Phenomenology · Physics 2018-05-16 C. Gnendiger , A. Signer

Proton beam therapy can potentially offer improved treatment for cancers of the head and neck and in paediatric patients. There has been a sharp uptake of proton beam therapy in recent years as improved delivery techniques and patient…

Computed Tomography (CT) imaging, while essential for diagnostics, exposes patients to ionizing radiation. To accurately quantify radiation dosage, this study introduces MIDSX, a specialized open-source Monte Carlo (MC) photon transport…

Medical Physics · Physics 2023-11-29 John Meneghini

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

Medical Physics · Physics 2019-12-23 Azar Sadeghnejad Barkousaraie , Olalekan Ogunmolu , Steve Jiang , Dan Nguyen

Purpose: To develop a knowledge-based voxel-wise dose prediction system using a convolution neural network for high-dose-rate brachytherapy cervical cancer treatments with a tandem-and-ovoid (T&O) applicator. Methods: A 3D U-NET was…

Background and Purpose: Increasing the number of arcs in volumetric modulated arc therapy (VMAT) allows for better intensity modulation and may improve plan quality. However, this leads to longer delivery times, which may cause patient…

Medical Physics · Physics 2025-10-31 Nathan Torelli , Madalyne Day , Jan Unkelbach

Charged Particle Therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbons. A critical issue is the monitoring of the dose released by the beam to the tumor and to the surrounding tissues. We present…

$\textbf{Purpose:}$ To assess the viability of a physics-based, deterministic and adjoint-capable algorithm for performing treatment planning system independent dose calculations and for computing dosimetric differences caused by anatomical…

Medical Physics · Physics 2024-04-02 Tiberiu Burlacu , Danny Lathouwers , Zoltán Perkó

Arrays of minibeams of protons and $^{12}$C in tissue-like media were modeled with Geant4 toolkit. A set of beam energies was used in simulations to provide a Spead-out Bragg peak (SOBP) extended by 6 cm in depth for protons as well as for…

Medical Physics · Physics 2024-09-23 I. A. Pshenichnov , U. A. Dmitrieva , S. D. Savenkov , A. O. Svetlichnyi

This work summarises the results of a comparison organized by EURADOS focused on the usage of the ICRP Reference Computational Phantoms. This activity aimed to provide training for the implementation of voxel phantoms in Monte Carlo…

We present a highly efficient molecular dynamics scheme for calculating the concentration depth profile of dopants in ion irradiated materials. The scheme incorporates several methods for reducing the computational overhead, plus a rare…

Computational Physics · Physics 2009-10-31 Keith M. Beardmore , Niels Gronbech-Jensen

The capability of standard Geant4 PhysicsLists to address the fragmentation of $^{12}$C$-^{12}$C was assessed through a comparative analysis with experimental cross sections reported by Divay et al. and Dudouet et al. The standard…

We developed a three-dimensional radiative transfer code for an ultra-relativistic background flow-field by using the Monte Carlo (MC) method in the context of gamma-ray burst (GRB) emission. For obtaining reliable simulation results in the…

High Energy Astrophysical Phenomena · Physics 2017-09-13 Ayako Ishii , Naofumi Ohnishi , Hiroki Nagakura , Hirotaka Ito , Shoichi Yamada

The many-body diffusion quantum Monte Carlo (DMC) method with twist-averaged boundary conditions is used to calculate the ground-state equation of state and the energetics of point defects in fcc aluminum using supercells up to 1331 atoms.…

Materials Science · Physics 2012-10-22 Randolph Q. Hood , P. R. C. Kent , Fernando A. Reboredo

In this study, the absorbed dose calculation for the cerebral region is refined using the Geant4 software, along with the ROOT and GATE programs. This approach provides a detailed statistical analysis of positron trajectories within a water…

Medical Physics · Physics 2025-05-06 Walter Sabalza-Castillejo , Miguel Martin-Landrove

In plasma edge simulations, the behavior of neutral particles is often described by a Boltzmann--BGK equation. Solving this kinetic equation and estimating the moments of its solution are essential tasks, typically carried out using Monte…

Numerical Analysis · Mathematics 2025-12-30 Zhirui Tang , Julian Koellermeier , Emil Løvbak , Giovanni Samaey

Collimator angle is usually rotated when planning volumetric modulated arc therapy (VMAT) due to the leakage of radiation between multi-leaf collimator (MLC) leaves. We studied the effect of the collimator angles on the results of…

Medical Physics · Physics 2015-03-13 Yong Ho Kim , Ha Ryung Park , Won Taek Kim , Dong Won Kim , Yongkan Ki , Juhye Lee , Jinsuk Bae , Dahl Park

Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…