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The development and approval of new treatments generates large volumes of results, such as summaries of efficacy and safety. However, it is commonly overlooked that analyzing clinical study data also produces data in the form of results.…

Computers and Society · Computer Science 2022-04-22 Joana M Barros , Lukas A Widmer , Mark Baillie , Simon Wandel

Integrative learning of multiple datasets has the potential to mitigate the challenge of small $n$ and large $p$ that is often encountered in analysis of big biomedical data such as genomics data. Detection of weak yet important signals can…

Methodology · Statistics 2022-07-04 Changgee Chang , Zongyu Dai , Jihwan Oh , Qi Long

Aggregation has been an important operation since the early days of relational databases. Today's Big Data applications bring further challenges when processing aggregation queries, demanding adaptive aggregation algorithms that can process…

Databases · Computer Science 2013-11-04 Jian Wen , Vinayak R. Borkar , Michael J. Carey , Vassilis J. Tsotras

We explore the hyperparameters and introduce a methodological framework to convert disease patterns from time series data of blood test results into correlation graphs for causal hypothesis exploration. The networks represent hypotheses…

Other Quantitative Biology · Quantitative Biology 2025-12-29 David Patrick Duys Montealegre , Alexander Fulton , Mahta Haghighat Ghahfarokhi , Abicumaran Uthamacumaran , Hector Zenil

Faced with the challenges of patient confidentiality and scientific reproducibility, research on machine learning for health is turning towards the conception of synthetic medical databases. This article presents a brief overview of…

We discuss the problem of extending data mining approaches to cases in which data points arise in the form of individual graphs. Being able to find the intrinsic low-dimensionality in ensembles of graphs can be useful in a variety of…

Social and Information Networks · Computer Science 2016-12-12 Karthikeyan Rajendran , Assimakis A. Kattis , Alexander Holiday , Risi Kondor , Ioannis G. Kevrekidis

The challenges of collecting medical data on neurological disorder diagnosis problems paved the way for learning methods with scarce number of samples. Due to this reason, one-shot learning still remains one of the most challenging and…

Neurons and Cognition · Quantitative Biology 2022-12-16 Oben Özgür , Arwa Rekik , Islem Rekik

Clinical data from electronic medical records, registries or trials provide a large source of information to apply machine learning methods in order to foster precision medicine, e.g. by finding new disease phenotypes or performing…

Machine Learning · Computer Science 2020-08-17 Maria Hügle , Gabriel Kalweit , Thomas Huegle , Joschka Boedecker

We consider the problem of aggregating models learned from sequestered, possibly heterogeneous datasets. Exploiting tools from Bayesian nonparametrics, we develop a general meta-modeling framework that learns shared global latent structures…

Machine Learning · Statistics 2019-11-04 Mikhail Yurochkin , Mayank Agarwal , Soumya Ghosh , Kristjan Greenewald , Trong Nghia Hoang

With the rapid development of large language models in recent years, there has been an increasing demand for domain-specific Agents that can cater to the unique needs of enterprises and organizations. Unlike general models, which strive for…

Computation and Language · Computer Science 2024-08-13 Chih-Wei Song , Yu-Kai Lee , Yin-Te Tsai

Large amount of data is often required to train and deploy useful machine learning models in industry. Smaller enterprises do not have the luxury of accessing enough data for machine learning, For privacy sensitive fields such as banking,…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-05 Felix Ongati , Eng. Lawrence Muchemi

Protecting user privacy is a major concern for many machine learning systems that are deployed at scale and collect from a diverse set of population. One way to address this concern is by collecting and releasing data labels in an…

Machine Learning · Computer Science 2023-05-19 Lin Chen , Gang Fu , Amin Karbasi , Vahab Mirrokni

In many machine learning tasks, models are trained to predict structure data such as graphs. For example, in natural language processing, it is very common to parse texts into dependency trees or abstract meaning representation (AMR)…

Computation and Language · Computer Science 2022-01-25 Hoang Thanh Lam , Gabriele Picco , Yufang Hou , Young-Suk Lee , Lam M. Nguyen , Dzung T. Phan , Vanessa López , Ramon Fernandez Astudillo

We address the goal of conducting inference about a smooth finite-dimensional parameter by utilizing individual-level data from various independent sources. Recent advancements have led to the development of a comprehensive theory capable…

Statistics Theory · Mathematics 2025-11-19 Ellen Graham , Marco Carone , Andrea Rotnitzky

When re-structuring patient cohorts into so-called population graphs, initially independent data points can be incorporated into one interconnected graph structure. This population graph can then be used for medical downstream tasks using…

Social and Information Networks · Computer Science 2023-09-20 Tamara T. Mueller , Sophie Starck , Leonhard F. Feiner , Kyriaki-Margarita Bintsi , Daniel Rueckert , Georgios Kaissis

The popularity of deep learning has led to the curation of a vast number of massive and multifarious datasets. Despite having close-to-human performance on individual tasks, training parameter-hungry models on large datasets poses…

Machine Learning · Computer Science 2023-09-27 Noveen Sachdeva , Julian McAuley

Meta-analysis, because of both logistical convenience and statistical efficiency, is widely popular for synthesizing information on common parameters of interest across multiple studies. We propose developing a generalized meta-analysis…

Methodology · Statistics 2018-11-27 Prosenjit Kundu , Runlong Tang , Nilanjan Chatterjee

Business Processes, i.e., a set of coordinated tasks and activities to achieve a business goal, and their continuous improvements are key to the operation of any organization. In banking, business processes are increasingly dynamic as…

Computers and Society · Computer Science 2020-09-30 Shahabodin Khadivi Zand

In some real-world applications, data samples are usually distributed on local devices, where federated learning (FL) techniques are proposed to coordinate decentralized clients without directly sharing users' private data. FL commonly…

Machine Learning · Computer Science 2024-04-16 Xin-Chun Li , Shaoming Song , Yinchuan Li , Bingshuai Li , Yunfeng Shao , Yang Yang , De-Chuan Zhan

Recent development of 3D sensors allows the acquisition of extremely dense 3D point clouds of large-scale scenes. The main challenge of processing such large point clouds remains in the size of the data, which induce expensive computational…

Computer Vision and Pattern Recognition · Computer Science 2021-09-24 Thomas Richard , Florent Dupont , Guillaume Lavoue