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Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…

Machine Learning · Statistics 2016-12-16 Cecilia S. Lee , Doug M. Baughman , Aaron Y. Lee

Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel S. Schuman , Rahil Garnavi

Optical coherence tomography (OCT) is a non-invasive imaging technology which can provide micrometer-resolution cross-sectional images of the inner structures of the eye. It is widely used for the diagnosis of ophthalmic diseases with…

Image and Video Processing · Electrical Eng. & Systems 2019-12-10 Donghuan Lu , Morgan Heisler , Da Ma , Setareh Dabiri , Sieun Lee , Gavin Weiguang Ding , Marinko V. Sarunic , Mirza Faisal Beg

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mike Pekala , Neil Joshi , David E. Freund , Neil M. Bressler , Delia Cabrera DeBuc , Philippe M Burlina

Segmentation of retinal layers from Optical Coherence Tomography (OCT) volumes is a fundamental problem for any computer aided diagnostic algorithm development. This requires preprocessing steps such as denoising, region of interest…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Karthik Gopinath , Samrudhdhi B Rangrej , Jayanthi Sivaswamy

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

In this paper, we introduce robust and synergetic hand-crafted features and a simple but efficient deep feature from a convolutional neural network (CNN) architecture for defocus estimation. This paper systematically analyzes the…

Computer Vision and Pattern Recognition · Computer Science 2017-05-01 Jinsun Park , Yu-Wing Tai , Donghyeon Cho , In So Kweon

Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images…

Ophthalmic diseases represent a significant global health issue, necessitating the use of advanced precise diagnostic tools. Optical Coherence Tomography (OCT) imagery which offers high-resolution cross-sectional images of the retina has…

Artificial Intelligence · Computer Science 2024-09-27 Md. Touhidul Islam , Md. Abtahi Majeed Chowdhury , Mahmudul Hasan , Asif Quadir , Lutfa Aktar

Optical Coherence Tomography is a technique used to scan the Retina of the eye and check for tears. In this paper, we develop a Convolutional Neural Network Architecture for OCT scan classification. The model is trained to detect Retinal…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Adit Magotra , Aagat Gedam , Tanush Savadi , Emily Li

Purpose: To develop a deep learning approach to de-noise optical coherence tomography (OCT) B-scans of the optic nerve head (ONH). Methods: Volume scans consisting of 97 horizontal B-scans were acquired through the center of the ONH using a…

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Optical coherence tomography (OCT) is commonly used to analyze retinal layers for assessment of ocular diseases. In this paper, we propose a method for retinal layer segmentation and quantification of uncertainty based on Bayesian deep…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Suman Sedai , Bhavna Antony , Dwarikanath Mahapatra , Rahil Garnavi

Optical coherence tomography (OCT) is a commonly-used method of extracting high resolution retinal information. Moreover there is an increasing demand for the automated retinal layer segmentation which facilitates the retinal disease…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Zeyu Fu , Yang Sun , Xiangyu Zhang , Scott Stainton , Shaun Barney , Jeffry Hogg , William Innes , Satnam Dlay

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia
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