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Related papers: Alchemical normal modes unify chemical space

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Normal mode analysis offers an efficient way of modeling the conformational flexibility of protein structures. Simple models defined by contact topology, known as elastic network models, have been used to model a variety of systems, but the…

Biomolecules · Quantitative Biology 2007-05-23 Dmitry A. Kondrashov , Adam W. Van Wynsberghe , Ryan M. Bannen , Qiang Cui , George N. Phillips

Recent experiments indicate that doping low concentrations of bent-core molecules into calamitic smectic solvents can induce anticlinic and biaxial smectic phases. We have carried out Monte Carlo (MC) simulations of mixtures of rodlike…

Statistical Mechanics · Physics 2009-11-07 Prabal K. Maiti , Yves Lansac , Matthew A. Glaser , Noel A. Clark

Chemical compound space (CCS), the set of all theoretically conceivable combinations of chemical elements and (meta-)stable geometries that make up matter, is colossal. The first principles based virtual sampling of this space, for example…

Chemical Physics · Physics 2021-06-23 Bing Huang , O. Anatole von Lilienfeld

The adatom arrays on surfaces offer an ideal playground to explore the mechanisms of chemical bonding via changes in the local electronic tunneling spectra. While this information is readily available in hyperspectral scanning tunneling…

The Boltzmann Machine (BM) is a neural network composed of stochastically firing neurons that can learn complex probability distributions by adapting the synaptic interactions between the neurons. BMs represent a very generic class of…

Mesoscale and Nanoscale Physics · Physics 2021-09-16 Brian Kiraly , Elze J. Knol , Hilbert J. Kappen , Alexander A. Khajetoorians

We study alchemical atomic energy partitioning as a method to estimate atomisation energies from atomic contributions which are defined in physically rigorous and general ways through use of the uniform electron gas as a joint reference. We…

At low temperature, information can be stored in the orientation of the localized magnetic moment of an adatom. However, scattering of electrons and phonons with the nanomagnet leads its state to have incoherent classical dynamics and might…

Mesoscale and Nanoscale Physics · Physics 2017-03-28 M. Marciani , C. Hübner , B. Baxevanis

A novel approach is presented for the solution of instantaneous chemical equilibrium problems. The chemical equilibrium can be considered, due to its intrinsically local character, as a mapping of the three-dimensional parameter space…

Astrophysics · Physics 2009-11-11 A. Asensio Ramos , H. Socas-Navarro

Nanophotonics enables unprecedented control over light-matter interactions, yet conventional isotropic materials limit the spectral range and mode response in subwavelength structures. Anisotropic nanoparticles -- ubiquitous in natural and…

Applied Physics · Physics 2025-12-29 Asaf Farhi , Haim Suchowski

On-chip integration of highly anisotropic two-dimensional (2D) materials offers new opportunities for realizing high performance polarization selective devices. Obtaining optimized designs for such devices requires extensively sweeping…

Because anomalous samples cannot be used for training, many anomaly detection and localization methods use pre-trained networks and non-parametric modeling to estimate encoded feature distribution. However, these methods neglect the impact…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Jaehyeok Bae , Jae-Han Lee , Seyun Kim

This brief sketches initial progress towards a unified energy-based solution for the semi-supervised visual anomaly detection and localization problem. In this setup, we have access to only anomaly-free training data and want to detect and…

Machine Learning · Computer Science 2021-05-10 Ergin Utku Genc , Nilesh Ahuja , Ibrahima J Ndiour , Omesh Tickoo

We design and successfully implement artificial neural networks (ANNs) to detect and classify entanglement for three-qubit systems using limited state features. The overall design principle is a feed forward neural network (FFNN), with the…

Quantum Physics · Physics 2024-11-19 Jorawar Singh , Vaishali Gulati , Kavita Dorai , Arvind

The requirement for accelerated and quantitatively accurate screening of nuclear magnetic resonance spectra across the small molecules chemical compound space is two-fold: (1) a robust `local' machine learning (ML) strategy capturing the…

Chemical Physics · Physics 2020-12-04 Amit Gupta , Sabyasachi Chakraborty , Raghunathan Ramakrishnan

In drug discovery, predicting the absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of small-molecule drugs is critical for ensuring safety and efficacy. However, the process of accurately predicting these…

Machine Learning · Computer Science 2026-03-27 Bohao Xu , Yingzhou Lu , Chenhao Li , Ling Yue , Xiao Wang , Tianfan Fu , Minjie Shen , Lulu Chen

Machine learning techniques are increasingly used to predict material behavior in scientific applications and offer a significant advantage over conventional numerical methods. In this work, an Artificial Neural Network (ANN) model is used…

Computational Engineering, Finance, and Science · Computer Science 2022-09-08 Olivier Pantalé , Pierre Tize Mha , Amèvi Tongne

Equilibrium structures determine material properties and biochemical functions. We propose to machine learn phase-space averages, conventionally obtained by {\em ab initio} or force-field based molecular dynamics (MD) or Monte Carlo…

Chemical Physics · Physics 2022-07-27 Jan Weinreich , Dominik Lemm , Guido Falk von Rudorff , O. Anatole von Lilienfeld

Coherent Elastic Neutrino-Nucleus Scattering (CE$\nu$NS) is a Standard Model process that, although predicted for decades, has only been detected recently by the COHERENT collaboration. Now that CE$\nu$NS has been discovered, it provides a…

High Energy Physics - Phenomenology · Physics 2018-11-14 Julien Billard , Joseph Johnston , Bradley J. Kavanagh

Enzymes are nano-scale machines that have evolved to drive chemical reactions out of equilibrium in the right place at the right time. Given the complexity and specificity of enzymatic function, bottom-up design of enzymes presents a…

Soft Condensed Matter · Physics 2025-05-28 Michalis Chatzittofi , Jaime Agudo-Canalejo , Ramin Golestanian

Direct comparison of scanning tunneling microscopy and high resolution core level photo-emission experiments provides a rationale for the mechanism of formation of a two dimensional (2D) binary alloy (1/3 mono-layer (ML) Sn(1-…

Materials Science · Physics 2007-05-23 L. Ottaviano , G. Profeta , L. Petaccia , C. Nacci , S. Santucci , A. Pesci , M. Pedio