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Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom…

Image and Video Processing · Electrical Eng. & Systems 2019-07-25 Rhona Asgari , José Ignacio Orlando , Sebastian Waldstein , Ferdinand Schlanitz , Magdalena Baratsits , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Glaucoma is the second driving reason for partial or complete blindness among all the visual deficiencies which mainly occurs because of excessive pressure in the eye due to anxiety or depression which damages the optic nerve and creates…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Touhidul Islam Chayan , Anita Islam , Eftykhar Rahman , Md. Tanzim Reza , Tasnim Sakib Apon , MD. Golam Rabiul Alam

In medical science, the use of computer science in disease detection and diagnosis is gaining popularity. Previously, the detection of disease used to take a significant amount of time and was less reliable. Machine learning (ML) techniques…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Nowshin Tasnim , Mahmudul Hasan , Ishrak Islam

This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Manoj S H , Arya A Bosale

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

Quantitative Methods · Quantitative Biology 2021-12-16 David Le , Minhaj Alam , Cham Yao , Jennifer I. Lim , R. V. P. Chan , Devrim Toslak , Xincheng Yao

Automated surface segmentation of retinal layer is important and challenging in analyzing optical coherence tomography (OCT). Recently, many deep learning based methods have been developed for this task and yield remarkable performance.…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Hong Liu , Dong Wei , Donghuan Lu , Yuexiang Li , Kai Ma , Liansheng Wang , Yefeng Zheng

Deep learning has successfully been leveraged for medical image segmentation. It employs convolutional neural networks (CNN) to learn distinctive image features from a defined pixel-wise objective function. However, this approach can lead…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Kibrom Berihu Girum , Gilles Créhange , Alain Lalande

Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince

The optic nerve head represents the intraocular section of the optic nerve (ONH), which is prone to damage by intraocular pressure. The advent of optical coherence tomography (OCT) has enabled the evaluation of novel optic nerve head…

Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…

Automated medical image segmentation is an important step in many medical procedures. Recently, deep learning networks have been widely used for various medical image segmentation tasks, with U-Net and generative adversarial nets (GANs)…

Image and Video Processing · Electrical Eng. & Systems 2020-01-09 Balamurali Murugesan , Kaushik Sarveswaran , Vijaya Raghavan S , Sharath M Shankaranarayana , Keerthi Ram , Mohanasankar Sivaprakasam

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Glaucoma is a severe blinding disease, for which automatic detection methods are urgently needed to alleviate the scarcity of ophthalmologists. Many works have proposed to employ deep learning methods that involve the segmentation of optic…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Yanni Wang , Gang Yang , Dayong Ding , Jianchun Zao

Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images…

This study introduces the Hybrid Multi-modal VGG (HM-VGG) model, a cutting-edge deep learning approach for the early diagnosis of glaucoma. The HM-VGG model utilizes an attention mechanism to process Visual Field (VF) data, enabling the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Junliang Du , Yiru Cang , Tong Zhou , Jiacheng Hu , Weijie He

Diabetic Retinopathy (DR), an ocular complication of diabetes, is a leading cause of blindness worldwide. Traditionally, DR is monitored using Color Fundus Photography (CFP), a widespread 2-D imaging modality. However, DR classifications…

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Age-related Macular Degeneration (AMD) is the predominant cause of blindness in developed countries, specially in elderly people. Moreover, its prevalence is increasing due to the global population ageing. In this scenario, early detection…

Image and Video Processing · Electrical Eng. & Systems 2022-05-24 José Morano , Álvaro S. Hervella , José Rouco , Jorge Novo , José I. Fernández-Vigo , Marcos Ortega

Generative AI for automated glaucoma diagnostic report generation faces two predominant challenges: content redundancy in narrative outputs and inadequate highlighting of pathologically significant features including optic disc cupping,…

Computational Engineering, Finance, and Science · Computer Science 2025-10-14 Cheng Huang , Weizheng Xie , Zeyu Han , Tsengdar Lee , Karanjit Kooner , Jui-Ka Wang , Ning Zhang , Jia Zhang

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Md. Aiyub Ali , Md. Shakhawat Hossain , Md. Kawar Hossain , Subhadra Soumi Sikder , Sharun Akter Khushbu , Mirajul Islam