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Design of experiments has traditionally relied on the frequentist hypothesis testing framework where the optimal size of the experiment is specified as the minimum sample size that guarantees a required level of power. Sample size…

Methodology · Statistics 2025-08-07 Shirin Golchi , Luke Hagar

Due to their parsimony, separable covariance models have been popular in modeling matrix-variate data. However, the inference from such a model may be misleading if the population covariance matrix $\Sigma$ is actually non-separable,…

Statistics Theory · Mathematics 2026-05-05 Bongjung Sung , Peter D. Hoff

Bayesian network (BN) structure discovery algorithms typically either make assumptions about the sparsity of the true underlying network, or are limited by computational constraints to networks with a small number of variables. While these…

Machine Learning · Statistics 2023-07-14 Luke Duttweiler , Sally W. Thurston , Anthony Almudevar

Covariance matrix estimation, a classical statistical topic, poses significant challenges when the sample size is comparable to or smaller than the number of features. In this paper, we frame covariance matrix estimation as a compound…

Methodology · Statistics 2025-03-04 Huqin Xin , Sihai Dave Zhao

Variable selection for structured covariates lying on an underlying known graph is a problem motivated by practical applications, and has been a topic of increasing interest. However, most of the existing methods may not be scalable to high…

Methodology · Statistics 2016-04-27 Changgee Chang , Suprateek Kundu , Qi Long

A common task in high-throughput biology is to test for differences in means between two samples across thousands of features (e.g., genes or proteins), often with only a handful of replicates per sample. Moderated t-tests handle this…

Methodology · Statistics 2025-10-02 Wanyi Ling , Wufang Hong , Nikolaos Ignatiadis

Physics-based covariance models provide a systematic way to construct covariance models that are consistent with the underlying physical laws in Gaussian process analysis. The unknown parameters in the covariance models can be estimated…

Computation · Statistics 2023-03-20 Yian Chen , Mihai Anitescu

Over the last two decades, many exciting variable selection methods have been developed for finding a small group of covariates that are associated with the response from a large pool. Can the discoveries from these data mining approaches…

Statistics Theory · Mathematics 2017-07-24 Jianqing Fan , Qi-Man Shao , Wen-Xin Zhou

There has been a tremendous methodological development of Bayes factors for hypothesis testing in the social and behavioral sciences, and related fields. This development is due to the flexibility of the Bayes factor for testing multiple…

In high-dimensions, many variable selection methods, such as the lasso, are often limited by excessive variability and rank deficiency of the sample covariance matrix. Covariance sparsity is a natural phenomenon in high-dimensional…

Methodology · Statistics 2010-06-08 X. Jessie Jeng And Z. John Daye

This article presents a homogeneity test for testing the equality of several high-dimensional covariance matrices for stationary processes with ignoring the assumption of normality. We give the asymptotic distribution of the proposed test.…

Statistics Theory · Mathematics 2020-08-24 Abdullah Qayed , Dong Han

Despite their importance in supporting experimental conclusions, standard statistical tests are often inadequate for research areas, like the life sciences, where the typical sample size is small and the test assumptions difficult to…

Methodology · Statistics 2011-04-15 Pietro Berkes , Jozsef Fiser

Colocalization analyses assess whether two traits are affected by the same or distinct causal genetic variants in a single gene region. A class of Bayesian colocalization tests are now routinely used in practice; for example, for genetic…

Methodology · Statistics 2024-02-20 Ashish Patel , John C. Whittaker , Stephen Burgess

We present a new test of hypothesis in which we seek the probability of the null conditioned on the data, where the null is a simplification undertaken to counter the intractability of the more complex model, that the simpler null model is…

Applications · Statistics 2016-09-20 Dalia Chakrabarty

Software faults are commonly occurred due to interactions between one or more input parameters in complex software systems. Software test design techniques can be implemented to ensure the quality of the developed software. Exhaustive…

Software Engineering · Computer Science 2021-08-03 Khin Maung Htay , Rozmie Razif Othman , Amiza Amir , Hasneeza Liza Zakaria , Nuraminah Ramli

We analyze control of the familywise error rate (FWER) in a multiple testing scenario with a great many null hypotheses about the distribution of a high-dimensional random variable among which only a very small fraction are false, or…

Methodology · Statistics 2015-09-15 Kamel Lahouel , Donald Geman , Laurent Younes

We consider the problem of estimating high-dimensional covariance matrices of $K$-populations or classes in the setting where the sample sizes are comparable to the data dimension. We propose estimating each class covariance matrix as a…

Methodology · Statistics 2022-02-08 Elias Raninen , David E. Tyler , Esa Ollila

Inferences about hypotheses are ubiquitous in the cognitive sciences. Bayes factors provide one general way to compare different hypotheses by their compatibility with the observed data. Those quantifications can then also be used to choose…

In the context of testing general relativity with gravitational waves, constraints obtained with multiple events are typically combined either through a hierarchical formalism or though a combined multiplicative Bayes factor. We show that…

General Relativity and Quantum Cosmology · Physics 2022-08-17 Maximiliano Isi , Will M. Farr , Katerina Chatziioannou

We obtain the optimal Bayesian minimax rate for the unconstrained large covariance matrix of multivariate normal sample with mean zero, when both the sample size, n, and the dimension, p, of the covariance matrix tend to infinity.…

Statistics Theory · Mathematics 2017-12-04 Kyoungjae Lee , Jaeyong Lee
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