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Network-based epidemic models have been extensively employed to understand the spread of infectious diseases, but have generally overlooked the fact that most realistic networks are dynamical rather than static. In this paper, we study a…

Physics and Society · Physics 2019-02-19 Xiao-Long Peng , Ze-Qiong Zhang , Junyuan Yang , Zhen Jin

We propose a framework for the description of the effects of vaccinations on the spreading of an epidemic disease. Different vaccines can be dosed, each providing different immunization times and immunization levels. Differences due to…

Analysis of PDEs · Mathematics 2024-07-23 Rinaldo M. Colombo , Mauro Garavello

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

Optimization and Control · Mathematics 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

In this paper, we develop a multi-group epidemic framework via virtual dispersal where the risk of infection is a function of the residence time and local environmental risk. This novel approach eliminates the need to define and measure…

Populations and Evolution · Quantitative Biology 2015-04-01 Derdei Bichara , Yun Kang , Carlos Castillo-Chavez , Richard Horan , Charles Perrings

The containment of epidemic spreading is a major challenge in science. Vaccination, whenever available, is the best way to prevent the spreading, because it eventually immunizes individuals. However, vaccines are not perfect, and total…

This paper investigates optimal vaccination strategies in a metapopulation epidemic model. We consider a linear cost to better capture operational considerations, such as the total number of vaccines or hospitalizations, in contrast to the…

Optimization and Control · Mathematics 2025-06-03 Lucas Machado Moschen , Maria Soledad Aronna

We study the allocation of shared resources over multiple rounds among competing agents, via the dynamic max-min fair (DMMF) mechanism: the good in each round is allocated to the requesting agent with the least number of allocations…

Computer Science and Game Theory · Computer Science 2025-06-13 Giannis Fikioris , Siddhartha Banerjee , Éva Tardos

We consider three regions with different public health conditions. In the absence of migration among these regions, the first two have good health conditions and the disease free state is stable; for the third region, on the other hand, the…

Populations and Evolution · Quantitative Biology 2017-12-22 Fabio A. C. C. Chalub , Tiago J. Costa , Paula Patrício

In this paper, an optimal resource allocation framework is proposed for the allocation of critical medical resources among different units during a pandemic. The framework is developed by considering the dynamics of Pandemic, hierarchical…

Systems and Control · Electrical Eng. & Systems 2022-03-14 Shuvrangshu Jana , Rudrashis Majumder , Debasish Ghose

Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity. In some disease systems, the process of waning immunity can be…

Populations and Evolution · Quantitative Biology 2017-08-10 Tiffany Leung , Barry D Hughes , Federico Frascoli , Patricia T Campbell , James M McCaw

The location of the unique supremum of a stationary process on an interval does not need to be uniformly distributed over that interval. We describe all possible distributions of the supremum location for a broad class of such stationary…

Probability · Mathematics 2011-10-10 Gennady Samorodnitsky , Yi Shen

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

Populations and Evolution · Quantitative Biology 2020-11-06 Hernán De Battista , José García-Clúa , Sebastián Nuñez , Fernando Inthamoussou , Fabricio Garelli

This paper presents a discrete time probabilistic dynamic for simulating a contact-based epidemic spreading based on discrete time Markov chain process, in particular the attention is addressed to the susceptible-infectious-removed (SIR)…

Physics and Society · Physics 2017-12-22 Fabrizio Angaroni

We propose a deterministic compartmental model of infectious disease which considers the test-kits as an important ingredient for the suppression and mitigation of epidemics. A rigorous simulation (with analytical argument) is provided to…

Physics and Society · Physics 2021-07-28 Subrata Ghosh , Abhishek Senapati , Joydev Chattopadhyay , Chittaranjan Hens , Dibakar Ghosh

As infectious disease outbreaks emerge, public health agencies often enact vaccination and social distancing measures to slow transmission. Their success depends on not only strategies and resources, but also public adherence. Individual…

Physics and Society · Physics 2018-08-20 José L. Herrera , Lauren Ancel Meyers

Intent of this research is to explore how mathematical models, specifically Susceptible-Infected-Removed (SIR) model, can be utilized to forecast peak outbreak timeline of COVID-19 epidemic amongst a population of interest starting from the…

Populations and Evolution · Quantitative Biology 2020-09-14 Amit Tewari

We analyze a periodically-forced dynamical system inspired by the SIR model with impulsive vaccination. We fully characterize its dynamics according to the proportion $p$ of vaccinated individuals and the time $T$ between doses. If the…

Dynamical Systems · Mathematics 2024-08-02 João P. S. Maurício de Carvalho , Alexandre A. Rodrigues

We present a detailed set-based analysis of the well-known SIR and SEIR epidemic models subjected to hard caps on the proportion of infective individuals, and bounds on the allowable intervention strategies, such as social distancing,…

Optimization and Control · Mathematics 2021-11-17 Willem Esterhuizen , Jean Lévine , Stefan Streif

Understanding how the network topology affects the spread of an epidemic is a main concern in order to develop efficient immunization strategies. While there is a great deal of work dealing with the macroscopic topological properties of the…

Social and Information Networks · Computer Science 2023-01-02 Debayan Chakraborty , Anurag Singh , Hocine Cherifi

We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and…

Populations and Evolution · Quantitative Biology 2022-06-28 Omar El Deeb , Maya Jalloul