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We consider a susceptible, infected, removed (SIR) system where the transmission rate may be temporarily reduced for a fixed amount of time. We show that in order to minimize the total number of fatalities, the transmission rate should be…
Nowadays, epidemic models provide an appropriate tool for describing the propagation of biological viruses in human or animal populations, or rumours and other kinds of information in social networks and malware in both computer and ad hoc…
We propose and solve an optimal vaccination problem within a deterministic compartmental model of SIRS type: the immunized population can become susceptible again, e.g.\ because of a not complete immunization power of the vaccine. A social…
We present a SIR+ASI epidemic model to describe the interaction between human and dengue fever mosquito populations. A control strategy in the form of vaccination, to decrease the number of infected individuals, is used. An optimal control…
Efficient allocation of limited medical resources is crucial for controlling epidemic spreading on networks. Based on the susceptible-infected-susceptible model, we solve an optimization problem as how best to allocate the limited resources…
Now that SARS-CoV-2 (COVID-19) vaccines are developed, it is very important to plan its distribution strategy. In this paper, we formulated a multi-objective linear programming model to optimize vaccine distribution and applied it to the…
The problem of targeted network immunization can be defined as the one of finding a subset of nodes in a network to immunize or vaccinate in order to minimize a tradeoff between the cost of vaccination and the final (stationary) expected…
In this study, we explore the dynamic interplay between the timing of vaccination campaigns and the trajectory of disease spread in a population. Through comprehensive data analysis and modeling, we have uncovered a counter-intuitive…
In the Susceptible-Infectious-Recovered (SIR) model of disease spreading, the time to extinction of the epidemics happens at an intermediate value of the per-contact transmission probability. Too contagious infections burn out fast in the…
This research introduces a new approach utilizing optimal control theory (OCT) to assess the Social Optimum (SO) of a vaccination game, navigating the intricate considerations of cost, availability, and distribution policies. By integrating…
We analyze infection spreading processes in a system where only a fraction $p$ of individuals can be affected by disease, while remaining $1-p$ individuals are immune. Such a picture can emerge as a natural consequence of previously…
The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United…
In this study, we present an immuno-epidemic model to understand mitigation options during an epidemic break. The model incorporates comorbidity and multiple-vaccine doses through a system of coupled integro-differential equations to…
We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…
The waning of immunity after recovery or vaccination is a major factor accounting for the severity and prolonged duration of an array of epidemics, ranging from COVID-19 to diphtheria and pertussis. To study the effectiveness of different…
We develop a mechanistic model that classifies individuals both in terms of epidemiological status (SIR) and vaccination attitude (willing or unwilling), with the goal of discovering how disease spread is influenced by changing opinions…
Early on during a pandemic, vaccine availability is limited, requiring prioritisation of different population groups. Evaluating vaccine allocation is therefore a crucial element of pandemics response. In the present work, we develop a…
Simulations of infectious disease spread have long been used to understand how epidemics evolve and how to effectively treat them. However, comparatively little attention has been paid to understanding the fairness implications of different…
We propose a model describing the synergetic feedback between word-of-mouth (WoM) and epidemic dynamics controlled by voluntary vaccination. We combine a game-theoretic model for the spread of WoM and a compartmental model describing $SIR$…
We investigate three aspects of the importance of nodes with respect to Susceptible-Infectious-Removed (SIR) disease dynamics: influence maximization (the expected outbreak size given a set of seed nodes), the effect of vaccination (how…