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Morphing is the process of changing one figure into another. Some numerical methods of 3D surface morphing by deformable modeling and conformal mapping are shown in this study. It is well known that there exists a unique Riemann conformal…

Graphics · Computer Science 2015-04-02 Mei-Heng Yueh , Xianfeng David Gu , Wen-Wei Lin , Chin-Tien Wu , Shing-Tung Yau

In this paper, we described a set of computational technologies for image analysis with applications in Brain Morphometry. The proposed technologies are based on a new Variational Principle which constructs a transformation with prescribed…

Computational Geometry · Computer Science 2018-10-31 Zicong Zhou , Ben Hildebrandt , Xi Chen , Guojun Liao

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

Brain decoding is a field of computational neuroscience that uses measurable brain activity to infer mental states or internal representations of perceptual inputs. Therefore, we propose a novel approach to brain decoding that also relies…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Matteo Ferrante , Tommaso Boccato , Nicola Toschi

Brain aging is a regional phenomenon, a facet that remains relatively under-explored within the realm of brain age prediction research using machine learning methods. Voxel-level predictions can provide localized brain age estimates that…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Neha Gianchandani , Mahsa Dibaji , Johanna Ospel , Fernando Vega , Mariana Bento , M. Ethan MacDonald , Roberto Souza

In this study we propose a deformation-based framework to jointly model the influence of aging and Alzheimer's disease (AD) on the brain morphological evolution. Our approach combines a spatio-temporal description of both processes into a…

Neurons and Cognition · Quantitative Biology 2019-05-27 Raphaël Sivera , Hervé Delingette , Marco Lorenzi , Xavier Pennec , Nicholas Ayache

Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that…

Methodology · Statistics 2015-06-18 Brian P. Kent , Alessandro Rinaldo , Fang-Cheng Yeh , Timothy Verstynen

Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, most tools for estimating cortical surfaces work exclusively…

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

In this paper, we present a novel region-based segmentation method for cortical spreading depressions in 2-photon microscopy images. Fluorescent microscopy has become an important tool in neuroscience, but segmentation approaches are…

Image and Video Processing · Electrical Eng. & Systems 2019-02-04 M. Filip Sluzewski , Petr Tvrdik , Scott T. Acton

A core goal of functional neuroimaging is to study how the environment is processed in the brain. The mainstream paradigm involves concurrently measuring a broad spectrum of brain responses to a small set of environmental features…

Neurons and Cognition · Quantitative Biology 2021-06-14 Pedro F. da Costa , Rianne Haartsen , Elena Throm , Luke Mason , Anna Gui , Robert Leech , Emily J. H. Jones

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser

The correct reconstruction of individual (crossing) nerve fibers is a prerequisite when constructing a detailed network model of the brain. The recently developed technique Scattered Light Imaging (SLI) allows the reconstruction of crossing…

Biological Physics · Physics 2021-11-30 Miriam Menzel , Marouan Ritzkowski , Jan André Reuter , David Gräßel , Katrin Amunts , Markus Axer

Reconstructing visual stimuli from human brain activity (e.g., fMRI) bridges neuroscience and computer vision by decoding neural representations. However, existing methods often overlook critical brain structure-function relationships,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Sijin Yu , Zijiao Chen , Wenxuan Wu , Shengxian Chen , Zhongliang Liu , Jingxin Nie , Xiaofen Xing , Xiangmin Xu , Xin Zhang

Recent advances in molecular and genetic research have identified a diverse range of brain tumor sub-types, shedding light on differences in their molecular mechanisms, heterogeneity, and origins. The present study performs whole-brain…

Neurons and Cognition · Quantitative Biology 2024-07-26 Debanjali Bhattacharya , Ninad Aithal , Manish Jayswal , Neelam Sinha

Diffusion-weighted Magnetic Resonance Imaging (dMRI) is increasingly used to study the fetal brain in utero. An important computation enabled by dMRI is streamline tractography, which has unique applications such as tract-specific analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Camilo Calixto , Camilo Jaimes , Matheus D. Soldatelli , Simon K. Warfield , Ali Gholipour , Davood Karimi

Accurate compensation of brain deformation is a critical challenge for reliable image-guided neurosurgery, as surgical manipulation and tumor resection induce tissue motion that misaligns preoperative planning images with intraoperative…

Modern imaging techniques for probing brain function, including functional Magnetic Resonance Imaging, intrinsic and extrinsic contrast optical imaging, and magnetoencephalography, generate large data sets with complex content. In this…

Neurons and Cognition · Quantitative Biology 2009-11-10 P. P. Mitra , B. Pesaran

Recent advancements in medical image segmentation techniques have achieved compelling results. However, most of the widely used approaches do not take into account any prior knowledge about the shape of the biomedical structures being…

Image and Video Processing · Electrical Eng. & Systems 2019-09-18 Zhou He , Siqi Bao , Albert Chung