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Standard deviation measurements of intensity profiles of stationary single fluorescent molecules are useful for studying axial localization, molecular orientation, and a fluorescence imaging system's spatial resolution. Here we report on…

Quantitative Methods · Quantitative Biology 2015-05-13 Michael C. DeSantis , Shawn H. DeCenzo , Je-Luen Li , Y. M. Wang

We investigate the modification of photoluminescence (PL) from single semiconductor nanocrystal quantum dots (NCs) in proximity of metal and semiconducting Atomic Force Microscope (AFM) tips. The presence of the tip alters the radiative…

Chemical Physics · Physics 2016-09-28 Yuval Ebenstein , Eyal Yoskovitz , Ronny Costi , Asaf Aharoni , Uri Banin

Correlative light and electron microscopy promises to combine molecular specificity with nanoscale imaging resolution. However, there are substantial technical challenges including reliable co-registration of optical and electron images,…

The local density of states (LDOS) of electromagnetic field drives many basic processes associated to light-matter interaction such as the thermal emission of object, the spontaneous emission of quantum systems or the fluctuation-induced…

Optics · Physics 2024-06-12 Philippe Ben-Abdallah

Single photon detectors play a key role across several basic science and technology applications. While progress has been made in improving performance, single photon detectors that can maintain high performance while also resolving the…

Quantum Physics · Physics 2023-08-11 Steve M. Young , Mohan Sarovar , François Léonard

Single molecule microscopy has proven to be an effective tool to characterize the fluorophore-plasmonic structure interaction. However, as specific information is hidden in the emission, sophisticated evaluation is required. Here we…

Optics · Physics 2024-01-11 T. Novák , P. Bíró , Gy. Ferenc , D. Ungor , E. Czvik , Á. Deák , L. Janovák , M. Erdélyi

Evanescent light excitation is widely used in super-resolution fluorescence microscopy to confine light and reduce background noise. Herein we propose a method of exploiting evanescent light in the context of emission. When a fluorophore is…

Biological Physics · Physics 2015-09-30 N. Bourg , C. Mayet , G. Dupuis , T. Barroca , P. Bon , S. Lécart , E. Fort , S. Lévêque-Fort

Near-fields around nanophotonic structures and waveguides can be used to optically interface particles ranging from atoms and molecules to microscopic biological and synthetic particles. Due to the strong, non-linear dependence of the…

Characterizing a monolayer of biological molecules has been a major challenge. We demonstrate nanophotonic wave-guide enhanced Raman spectroscopy (NWERS) of monolayers in the near-infrared region, enabling real-time measurements of the…

Investigating the cellular internalization pathways of single molecules or single nano-objects is important to understanding cell-matter interactions and to applications in drug delivery and discovery. Imaging and tracking the motion of…

Biological Physics · Physics 2015-06-04 Guosong Hong , Justin Z. Wu , Joshua T. Robinson , Hailiang Wang , Bo Zhang , Hongjie Dai

A broad range of scientific and industrial disciplines require precise optical measurements at very low light levels. Single-photon detectors combining high efficiency and high time resolution are pivotal in such experiments. By using…

We provide an analytical solution to study the near field optical effect of a core-shell nanostructure in proximity to a flat surface, within quasi-static approximation. The distribution of electrostatic potential and field enhancement in…

Mesoscale and Nanoscale Physics · Physics 2014-01-30 Wenping Cui , Mingda Li , Zuyang Dai , Qingping Meng , Yimei Zhu

Strong light-matter interactions in localized nano-emitters when placed near metallic mirrors have been widely reported via spectroscopic studies in the optical far-field. Here, we report a near-field nano-spectroscopic study of the…

Single nanoparticle tracking using optical microscopy is a powerful technique with many applications in biology, chemistry and material sciences. Despite significant advances, localising objects with nanometric position accuracy in a…

Near-infrared fluorescence imaging offers improved spatial precision by reducing light scattering and absorption in tissue. Despite this key advantage, the NIR region is limited by the availability of fluorophores, most of which exhibit…

Optics · Physics 2025-04-03 Neelima Chacko , Menachem Motiei , Nitzan Dar , Rinat Ankri

In recent years several methods to overcome diffraction limit in the far field microscopy have been demonstrated. Still the problem of superresolution is reliably solved only for fluorescent microscopy, giving a resolution of up to 20-30nm.…

Optics · Physics 2013-09-03 Yu. V. Miklyaev , S. A. Asselborn , K. A. Zaytsev , M. Ya. Darscht

We present a novel method to extract the various contributions to the photonic local density of states from near-field fluorescence maps. The approach is based on the simultaneous mapping of the fluorescence intensity and decay rate, and on…

The use of photo-activated fluorescent molecules to create long sequences of low emitter-density diffraction-limited images enables high-precision emitter localization, but at the cost of low temporal resolution. We suggest combining…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Gili Dardikman-Yoffe , Yonina C. Eldar

We study the time evolution of a one-dimensional system of strongly correlated electrons (a 'sample') that is suddenly coupled to a smaller, initially empty system (a 'nanoprobe'), which can subsequently move along the system. Our purpose…

Strongly Correlated Electrons · Physics 2025-02-11 Tobias Blum , Reinhard M. Noack , Salvatore R. Manmana

Integrated opto-electronic devices have the potential to revolutionize information processing, with substantial increase in computing speed, seamless information transfer and reduction of energy consumption. A key missing unit for the…

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