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Plasmonic nano-objects have shown great potential in enhancing biological and chemical sensing, light harvesting and energy transfer, and optical and quantum computing to name a few. Therefore, an extensive effort has been vested in…

Recently, the implementation of plasmonic nanoantennas has opened new possibilities to investigate the nanoscale dynamics of individual biomolecules in living cell. However, studies have yet been restricted to single molecular species as…

Enhanced optical absorption of molecules in the vicinity of metallic nanostructures is key to a number of surface-enhanced spectroscopies and of great general interest to the fields of plasmonics and nano-optics. Yet, experimental access to…

Substituting noble metals for high-index dielectrics has recently been proposed as an alternative strategy in nanophotonics to design broadband optical resonators and circumvent the ohmic losses of plasmonic materials. In this report, we…

Imaging depth of optical microscopy has been fundamentally limited to millimeter or sub-millimeter due to light scattering. X-ray microscopy can resolve spatial details of few microns deeply inside a sample but the contrast resolution is…

Biological Physics · Physics 2015-06-17 Wenxiang Cong , Fenglin Liu , Chao Wang , Ge Wang

The study of optical phenomena on the subwavelength scale is becoming increasingly important in photonics, particularly in the fields of nanoemitters, photonic crystals and plasmonics. Subwavelength field patterns are evanescent and must…

In situ measurement of analytes for in vivo or in vitro systems has been challenging due to the bulky size of traditional analytical instruments. Also, frequent in vitro concentration measurements rely on fluorescence-based methods or…

The photonic local density of states (PLDOS) determines the light matter interaction strength in nanophotonic devices. For standard dielectric devices, the PLDOS is fundamentally limited by diffraction, but its precise dependence on the…

Quantum Physics · Physics 2021-09-15 Yoshinori Uemura , Masaru Irita , Yoshikazu Homma , Mark Sadgrove

Single-molecule microscopy has become an indispensable tool for biochemical analysis. The capability of characterizing distinct properties of individual molecules without averaging has provided us with a different perspective for the…

Applied Physics · Physics 2020-05-21 Miao-Hsuan Chien , Silvan Schmid

RAndom Temporal Signals (RATS) method has proven to be a useful and versatile method for measuring photoluminescence (PL) dynamics and fluorescence lifetime imaging (FLIM). Here, we present two fundamental development steps in the method.…

Optics · Physics 2023-02-15 Jiri Junek , Karel Zidek

Precise localization of nanoparticles within a cell is crucial to the understanding of cell-particle interactions and has broad applications in nanomedicine. Here, we report a proof-of-principle experiment for imaging individual…

We report modifications to the optical properties of fluorophores in the vicinity of noble metal nanotips. The fluorescence from small clusters of quantum dots has been imaged using an apertureless scanning near-field optical microscope.…

Other Condensed Matter · Physics 2008-04-28 N. I. Cade , F. Culfaz , L. Eligal , T. Ritman-Meer , F-M. Huang , F. Festy , D. Richards

The near field scanning optical microscopy (NSOM) is not only a tool for imaging of sub-diffraction limited objects but also a prominent characteristic tool for understanding the intrinsic properties of the nanostructures. In order to…

Materials Science · Physics 2016-09-21 A. K. Sivadasan , Kishore K. Madapu , Sandip Dhara

Tracking single molecules is instrumental for quantifying the transport of molecules and nanoparticles in biological samples, e.g., in brain drug delivery studies. Existing intensity-based localisation methods are not developed for imaging…

We introduce MINFLUX, a concept for localizing photon emitters in space. By probing the emitter with a local intensity minimum of excitation light, MINFLUX minimizes the fluorescence photons needed for high localization precision. A 22-fold…

A recent study shows that: when a long lifetime particle is positioned near a plasmonic metal nanoparticle, lifetime of plasmon oscillations extends, but, "only" near that long-life particle [PRB 101, 035416 (2020)]. Here, we show that this…

Optics · Physics 2021-06-29 Rasim Volga Ovali , Ramazan Sahin , Alpan Bek , Mehmet Emre Tasgin

We demonstrate how optical nanofibers can be used to manipulate and probe single-atom fluorescence. We show that fluorescence photons from a very small number of atoms, average atom number of less than 0.1, around the nanofiber can readily…

Quantum Physics · Physics 2007-05-23 K. P. Nayak , P. N. Melentiev , M. Morinaga , Fam Le Kien , V. I. Balykin , K. Hakuta

Sensors that are able to detect and track single unlabelled biomolecules are an important tool both to understand biomolecular dynamics and interactions at nanoscale, and for medical diagnostics operating at their ultimate detection limits.…

Optics · Physics 2016-11-15 N. P. Mauranyapin , L. S. Madsen , M. A. Taylor , M. Waleed , W. P. Bowen

Molecular self-assembly, the function of biomembranes, and the performance of organic solar cells rely on molecular interactions on the nanoscale. The understanding and design of such intrinsic or engineered heterogeneous functional soft…

Chemical Physics · Physics 2013-12-30 Benjamin Pollard , Eric A. Muller , Karsten Hinrichs , Markus B. Raschke

Photonic nanostructures provide means of tailoring the interaction between light and matter and the past decade has witnessed a tremendous experimental and theoretical progress in this subject. In particular, the combination with…

Quantum Physics · Physics 2015-06-05 Peter Lodahl , Sahand Mahmoodian , Søren Stobbe