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Inferring microbial interaction networks from abundance patterns is an important approach to advance our understanding of microbial communities in general and the human microbiome in particular. Here we suggest discriminating two levels of…

Populations and Evolution · Quantitative Biology 2023-06-06 Isabella-Hilda Mendler , Barbara Drossel , Marc-Thorsten Hütt

The bootstrap is a popular and powerful method for assessing precision of estimators and inferential methods. However, for massive datasets which are increasingly prevalent, the bootstrap becomes prohibitively costly in computation and its…

Methodology · Statistics 2015-08-06 Srijan Sengupta , Stanislav Volgushev , Xiaofeng Shao

Statistical analysis of microbiome data is challenging. Bayesian multinomial logistic-normal (MLN) models have gained popularity due to their ability to account for the count compositional nature of these data, but existing approaches are…

Methodology · Statistics 2025-05-27 Tinghua Chen , Michelle Pistner Nixon , Justin D. Silverman

In contemporary data-driven environments, the generation and processing of multivariate time series data is an omnipresent challenge, often complicated by time delays between different time series. These delays, originating from a multitude…

Machine Learning · Computer Science 2024-08-26 Jiajie Wang , Zhiyuan Jerry Lin , Wen Chen

The bootstrap is a popular and convenient method for quantifying the authority of an empirical ordering of attributes, for example of a ranking of the performance of institutions or of the influence of genes on a response variable. In the…

Statistics Theory · Mathematics 2009-11-20 Peter Hall , Hugh Miller

The bootstrap provides a simple and powerful means of assessing the quality of estimators. However, in settings involving large datasets, the computation of bootstrap-based quantities can be prohibitively demanding. As an alternative, we…

Machine Learning · Computer Science 2012-07-03 Ariel Kleiner , Ameet Talwalkar , Purnamrita Sarkar , Michael Jordan

The analysis of data from multiple experiments, such as observations of several individuals, is commonly approached using mixed-effects models, which account for variation between individuals through hierarchical representations. This makes…

Computation · Statistics 2026-03-05 Henrik Häggström , Sebastian Persson , Marija Cvijovic , Umberto Picchini

Gut microbial composition has been linked to multiple health outcomes. Yet, temporal analysis of this composition had been limited to deterministic models. In this paper, we introduce a probabilistic model for the dynamics of intestinal…

Quantitative Methods · Quantitative Biology 2018-09-03 Ruiqi Zhong , Tyler Joseph , Joao B Xavier , Itsik Pe'er

We develop a new class of dynamic multivariate Poisson count models that allow for fast online updating and we refer to these models as multivariate Poisson-scaled beta (MPSB). The MPSB model allows for serial dependence in the counts as…

Methodology · Statistics 2016-09-16 Tevfik Aktekin , Nicholas G. Polson , Refik Soyer

Dropout represents a typical issue to be addressed when dealing with longitudinal studies. If the mechanism leading to missing information is non-ignorable, inference based on the observed data only may be severely biased. A frequent…

Methodology · Statistics 2018-03-23 Maria Francesca Marino , Marco Alfo'

Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thus an analytic approach that accounts for…

Missing data represents a fundamental challenge in machine learning applications, often reducing model performance and reliability. This problem is particularly acute in fields like bioinformatics and clinical machine learning, where…

Machine Learning · Computer Science 2025-09-04 Fatemeh Azad , Zoran Bosnić , Matjaž Kukar

This paper investigates the accuracy of bootstrap-based bias correction of persistence measures for long memory fractionally integrated processes. The bootstrap method is based on the semi-parametric sieve approach, with the dynamics in the…

Methodology · Statistics 2016-03-08 Simone D. Grose , Gael M. Martin , Donald S. Poskitt

We develop and implement a novel fast bootstrap for dependent data. Our scheme is based on the i.i.d. resampling of the smoothed moment indicators. We characterize the class of parametric and semi-parametric estimation problems for which…

Methodology · Statistics 2022-01-19 Davide La Vecchia , Alban Moor , Olivier Scaillet

The bulk of the research effort on brain connectivity revolves around statistical associations among brain regions, which do not directly relate to the causal mechanisms governing brain dynamics. Here we propose the multiscale causal…

Machine Learning · Computer Science 2024-03-21 Gabriele D'Acunto , Francesco Bonchi , Gianmarco De Francisci Morales , Giovanni Petri

Most real-world networks evolve over time. Existing literature proposes models for dynamic networks that are either unlabeled or assumed to have a single membership structure. On the other hand, a new family of Mixed Membership Stochastic…

Machine Learning · Computer Science 2023-04-13 Gaël Poux-Médard , Julien Velcin , Sabine Loudcher

The partially linear binary choice model can be used for estimating structural equations where nonlinearity may appear due to diminishing marginal returns, different life cycle regimes, or hectic physical phenomena. The inference procedure…

Econometrics · Economics 2023-12-01 Wenzheng Gao , Zhenting Sun

In this paper, we propose a bootstrap method applied to massive data processed distributedly in a large number of machines. This new method is computationally efficient in that we bootstrap on the master machine without over-resampling,…

Machine Learning · Statistics 2020-02-21 Yang Yu , Shih-Kang Chao , Guang Cheng

This work introduces a novel block bootstrap method for time series with multiple periodically correlated (MPC) components called the Variable Multiple Bandpass Periodic Block Bootstrap (VMBPBB). While past methodological advancements…

Methodology · Statistics 2025-07-10 Edward Valachovic

Dynamic prediction of time-to-event outcomes using longitudinal data is highly useful in clinical research and practice. A common strategy is the joint modeling of longitudinal and time-to-event data. The shared random effect model has been…

Methodology · Statistics 2025-05-27 Wenhao Li , Zhe Yin , Liang Li