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Background and Objectives: Predicting patient response to treatment and survival in oncology is a prominent way towards precision medicine. To that end, radiomics was proposed as a field of study where images are used instead of invasive…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Amine Amyar , Romain Modzelewski , Pierre Vera , Vincent Morard , Su Ruan

Colorectal cancer is one of the most common and lethal cancers and colorectal cancer liver metastases (CRLM) is the major cause of death in patients with colorectal cancer. Multifocality occurs frequently in CRLM, but is relatively…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Jianan Chen , Helen M. C. Cheung , Laurent Milot , Anne L. Martel

Medical head CT-scan imaging has been successfully combined with deep learning for medical diagnostics of head diseases and lesions[1]. State of the art classification models and algorithms for this task usually are based on 3d convolution…

Computer Vision and Pattern Recognition · Computer Science 2020-10-21 Luis Leal , Marvin Castillo , Fernando Juarez , Erick Ramirez , Mildred Aspuac , Diana Letona

Robust localization of lymph nodes (LNs) in multiparametric MRI (mpMRI) is critical for the assessment of lymphadenopathy. Radiologists routinely measure the size of LN to distinguish benign from malignant nodes, which would require…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tejas Sudharshan Mathai , Sungwon Lee , Thomas C. Shen , Zhiyong Lu , Ronald M. Summers

Purpose: Lymph nodes (LNs) in the chest have a tendency to enlarge due to various pathologies, such as lung cancer or pneumonia. Clinicians routinely measure nodal size to monitor disease progression, confirm metastatic cancer, and assess…

Image and Video Processing · Electrical Eng. & Systems 2024-01-15 Tejas Sudharshan Mathai , Bohan Liu , Ronald M. Summers

In the context of brain tumor characterization, we focused on two key questions: (a) stability of radiomics features to variability in multiregional segmentation masks obtained with fully-automatic deep segmentation methods and (b)…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Maria Nadeem , Asma Shaheen , Muhammad F. A. Chaudhary , Hassan Mohy-ud-Din

We developed a deep ensemble learning model with a radiomics spatial encoding execution for improved glioma segmentation accuracy using multi-parametric MRI (mp-MRI). This model was developed using 369 glioma patients with a 4-modality…

Quantitative Methods · Quantitative Biology 2023-03-21 Yang Chen , Zhenyu Yang , Jingtong Zhao , Justus Adamson , Yang Sheng , Fang-Fang Yin , Chunhao Wang

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Purpose: We developed an artificial neural network (ANN) combining radiomics with clinical and dosimetric features to predict the extent of body mass index (BMI) increase after surgery and proton therapy, with advantage of improved accuracy…

Medical Physics · Physics 2025-09-26 Wenjun Yang , Chia-Ho Hua , Tina Davis , Jinsoo Uh , Thomas E. Merchant

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Accurately predicting the treatment outcome plays a greatly important role in tailoring and adapting a treatment planning in cancer therapy. Although the development of different modalities and personalized medicine can greatly improve the…

Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening (LCS) using annual low-dose computed tomography (CT) scanning has been proven to significantly reduce lung cancer mortality by detecting cancerous…

Purpose: Convolutional neural networks (CNNs) are promising in predicting treatment outcome for pediatric craniopharyngioma while the decision mechanisms are difficult to interpret. We compared the activation maps of CNN with hand crafted…

Medical Physics · Physics 2025-09-26 Wenjun Yang , Chuang Wang , Tina Davis , Jinsoo Uh , Chia-Ho Hua , Thomas E. Merchant

Lung diseases including infections such as Pneumonia, Tuberculosis, and novel Coronavirus (COVID-19), together with Lung Cancer are significantly widespread and are, typically, considered life threatening. In particular, lung cancer is…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Parnian Afshar , Farnoosh Naderkhani , Anastasia Oikonomou , Moezedin Javad Rafiee , Arash Mohammadi , Konstantinos N. Plataniotis

Genetic studies have identified associations between gene mutations and clear cell renal cell carcinoma (ccRCC). Because the complete gene mutational landscape cannot be characterized through biopsy and sequencing assays for each patient,…

Accurate segmentation of brain tumors from 3D multimodal MRI is vital for diagnosis and treatment planning across diverse brain tumors. This paper addresses the challenges posed by the BraTS 2023, presenting a unified transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Ramy A. Zeineldin , Franziska Mathis-Ullrich

The treatment planning process for patients with head and neck (H&N) cancer is regarded as one of the most complicated due to large target volume, multiple prescription dose levels, and many radiation-sensitive critical structures near the…

Medical Physics · Physics 2019-03-27 Dan Nguyen , Xun Jia , David Sher , Mu-Han Lin , Zohaib Iqbal , Hui Liu , Steve Jiang

Purpose: Common to most MRSI techniques, the spatial resolution and the minimal scan duration of Deuterium Metabolic Imaging (DMI) are limited by the achievable SNR. This work presents a deep learning method for sensitivity enhancement of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Siyuan Dong , Henk M. De Feyter , Monique A. Thomas , Robin A. de Graaf , James S. Duncan

Accurate characterization of suspicious breast lesions in mammography is important for early diagnosis and treatment planning. While Convolutional Neural Networks (CNNs) are effective at extracting local visual patterns, they are less…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Mohammed Asad , Mohit Bajpai , Sudhir Singh , Rahul Katarya

Remarkable progress has been made in image recognition, primarily due to the availability of large-scale annotated datasets and the revival of deep CNN. CNNs enable learning data-driven, highly representative, layered hierarchical image…

Computer Vision and Pattern Recognition · Computer Science 2016-02-11 Hoo-Chang Shin , Holger R. Roth , Mingchen Gao , Le Lu , Ziyue Xu , Isabella Nogues , Jianhua Yao , Daniel Mollura , Ronald M. Summers
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