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One step in the conventional analysis of extracellularly recorded neuronal data is spike sorting, which separates electrical signal into action potentials from different neurons. Because spike sorting involves human judgment, it can be…

Neurons and Cognition · Quantitative Biology 2007-05-23 Artur Luczak , Nandakumar S. Narayanan

Spike sorting is essential for extracting neuronal information from neural signals and understanding brain function. With the advent of high-density microelectrode arrays (HDMEAs), the challenges and opportunities in multi-channel spike…

Signal Processing · Electrical Eng. & Systems 2024-12-30 Yuntao Han , Shiwei Wang , Alister Hamilton

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

Machine Learning · Computer Science 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

Understanding the function of complex cortical circuits requires the simultaneous recording of action potentials from many neurons in awake and behaving animals. Practically, this can be achieved by extracellularly recording from multiple…

Quantitative Methods · Quantitative Biology 2008-09-25 Ueli Rutishauser , Erin M. Schuman , Adam N. Mamelak

Spike sorting is a fundamental preprocessing step in neuroscience that is central to access simultaneous but distinct neuronal activities and therefore to better understand the animal or even human brain. But numerical complexity limits…

Machine Learning · Statistics 2019-07-01 Laurent Dragoni , Rémi Flamary , Karim Lounici , Patricia Reynaud-Bouret

Extracellular recordings are transient voltage fluctuations in the vicinity of neurons, serving as a fundamental modality in neuroscience for decoding brain activity at single-neuron resolution. Spike sorting, the process of attributing…

Signal Processing · Electrical Eng. & Systems 2026-01-13 Feng Cao , Zishuo Feng , Jicong Zhang , Wei Shi

Spike sorting is a valuable tool in understanding brain regions. It assigns detected spike waveforms to their origins, helping to research the mechanism of the human brain and the development of implantable brain-machine interfaces (iBMIs).…

Signal Processing · Electrical Eng. & Systems 2025-04-22 Xiaoyu Jiang , Tao Fang , Majid Zamani

Objective. Recent advancements in electrode designs and micro-fabrication technology has allowed existence of microelectrode arrays with hundreds of channels for single-cell recordings. In such electrophysiological recordings, each…

In many practical situations, the useful signal is contained in a low-dimensional subspace, drown in noise and interference. Many questions related to the estimation and detection of the useful signal arise. Because of their particular…

Statistics Theory · Mathematics 2014-05-20 Damien Passemier , Abla Kammoun , Mérouane Debbah

In this paper authors have presented a power efficient scheme for implementing a spike sorting module. Spike sorting is an important application in the field of neural signal acquisition for implantable biomedical systems whose function is…

Neural and Evolutionary Computing · Computer Science 2018-02-27 Anand Kumar Mukhopadhyay , Indrajit Chakrabarti , Arindam Basu , Mrigank Sharad

Many previous works in spike sorting study spike classification and compression independently. In this paper, a novel algorithm is proposed called MetaSort to address these two problems. To deal with compression, a novel adaptive level…

Signal Processing · Electrical Eng. & Systems 2026-03-10 Luca M. Meyer , Majid Zamani

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Christoph Stöckl , Wolfgang Maass

Spiking neural network (SNN) has been attached to great importance due to the properties of high biological plausibility and low energy consumption on neuromorphic hardware. As an efficient method to obtain deep SNN, the conversion method…

Computer Vision and Pattern Recognition · Computer Science 2022-07-07 Yang Li , Xiang He , Yiting Dong , Qingqun Kong , Yi Zeng

Neuromorphic computing has recently gained momentum with the emergence of various neuromorphic processors. As the field advances, there is an increasing focus on developing training methods that can effectively leverage the unique…

Emerging Technologies · Computer Science 2025-04-15 Sanaz Mahmoodi Takaghaj , Jack Sampson

Spikes can be easily detected inmostintracellular recordings as sharp peaks. However, insome experimental preparations,because of unipolar morphology or other characteristicsof the recorded neurons, the sizes of the spikes recorded from the…

Neurons and Cognition · Quantitative Biology 2021-11-23 Smith Gupta

The human visual system contains a hierarchical sequence of modules that take part in visual perception at superordinate, basic, and subordinate categorization levels. During the last decades, various computational models have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Fatemeh Sharifizadeh , Mohammad Ganjtabesh , Abbas Nowzari-Dalini

In electrophysiology, microelectrodes are the primary source for recording neural data of single neurons (single unit activity). These microelectrodes can be implanted individually, or in the form of microelectrodes arrays, consisting of…

Experimental studies support the notion of spike-based neuronal information processing in the brain, with neural circuits exhibiting a wide range of temporally-based coding strategies to rapidly and efficiently represent sensory stimuli.…

Neural and Evolutionary Computing · Computer Science 2020-08-18 Brian Gardner , André Grüning

Spiking Neural Networks (SNNs) promise efficient and dynamic spatio-temporal data processing. This paper reformulates a significant challenge in radio astronomy, Radio Frequency Interference (RFI) detection, as a time-series segmentation…

Neural and Evolutionary Computing · Computer Science 2026-01-23 Nicholas J. Pritchard , Andreas Wicenec , Mohammed Bennamoun , Richard Dodson