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Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering. Previous…

Molecular Networks · Quantitative Biology 2012-09-14 Kazuhiro Takemoto

Accurately determining and classifying the structure of complex networks is the focus of much current research. One class of network of particular interest are metabolic pathways, which have previously been studied from a graph theoretical…

Mathematical Physics · Physics 2012-10-10 Henry Dorrian , Kieran Smallbone , Jon borresen

Metabolism plays a central role in cell physiology because it provides the molecular machinery for growth. At the genome-scale, metabolism is made up of thousands of reactions interacting with one another. Untangling this complexity is key…

Molecular Networks · Quantitative Biology 2020-12-21 Varshit Dusad , Denise Thiel , Mauricio Barahona , Hector C. Keun , Diego A. Oyarzún

In this paper, we propose a novel meta learning approach for automatic channel pruning of very deep neural networks. We first train a PruningNet, a kind of meta network, which is able to generate weight parameters for any pruned structure…

Computer Vision and Pattern Recognition · Computer Science 2019-08-15 Zechun Liu , Haoyuan Mu , Xiangyu Zhang , Zichao Guo , Xin Yang , Tim Kwang-Ting Cheng , Jian Sun

Metabolic networks perform some of the most fundamental functions in living cells, including energy transduction and building block biosynthesis. While these are the best characterized networks in living systems, understanding their…

Molecular Networks · Quantitative Biology 2010-04-05 W. J. Riehl , P. L. Krapivsky , S. Redner , D. Segre

High-throughput techniques are leading to an explosive growth in the size of biological databases and creating the opportunity to revolutionize our understanding of life and disease. Interpretation of these data remains, however, a major…

Molecular Networks · Quantitative Biology 2009-11-11 Roger Guimera , Luis A. Nunes Amaral

It is often the case that the performance of a neural network can be improved by adding layers. In real-world practices, we always train dozens of neural network architectures in parallel which is a wasteful process. We explored $CompNet$,…

Neural and Evolutionary Computing · Computer Science 2018-04-30 Jun Lu , Wei Ma , Boi Faltings

Metagenomics has lowered the barrier to microbial discovery--enabling the identification of novel microbes without isolation--but cultures remain imperative for the deep study of microbes. Cultivation and isolation of non-model microbes…

Molecular Networks · Quantitative Biology 2026-02-26 Olivia Bulka , Chabname Ghassemi Nedjad , Loïc Paulevé , Sylvain Prigent , Clémence Frioux

Meta-learning often referred to as learning-to-learn is a promising notion raised to mimic human learning by exploiting the knowledge of prior tasks but being able to adapt quickly to novel tasks. A plethora of models has emerged in this…

Machine Learning · Computer Science 2022-10-17 Jicang Cai , Saeed Vahidian , Weijia Wang , Mohsen Joneidi , Bill Lin

This paper investigates how neurons can use metabolic cost to facilitate learning at a population level. Although decision-making by individual neurons has been extensively studied, questions regarding how neurons should behave to cooperate…

Neurons and Cognition · Quantitative Biology 2013-02-12 David Balduzzi , Pedro A Ortega , Michel Besserve

Self-replication is a key aspect of biological life that has been largely overlooked in Artificial Intelligence systems. Here we describe how to build and train self-replicating neural networks. The network replicates itself by learning to…

Artificial Intelligence · Computer Science 2018-05-28 Oscar Chang , Hod Lipson

Neural Networks are function approximators that have achieved state-of-the-art accuracy in numerous machine learning tasks. In spite of their great success in terms of accuracy, their large training time makes it difficult to use them for…

Machine Learning · Computer Science 2017-04-18 Abhishek Sinha , Mausoom Sarkar , Aahitagni Mukherjee , Balaji Krishnamurthy

[Background] Several studies have mentioned network modularity -- that a network can easily be decomposed into subgraphs that are densely connected within and weakly connected between each other -- as a factor affecting metabolic…

Molecular Networks · Quantitative Biology 2012-10-10 Petter Holme

Biological nervous systems are created in a fundamentally different way than current artificial neural networks. Despite its impressive results in a variety of different domains, deep learning often requires considerable engineering effort…

Neural and Evolutionary Computing · Computer Science 2023-07-18 Elias Najarro , Shyam Sudhakaran , Sebastian Risi

Metabolism is a fascinating cell machinery underlying life and disease and genome-scale reconstructions provide us with a captivating view of its complexity. However, deciphering the relationship between metabolic structure and function…

Molecular Networks · Quantitative Biology 2011-09-12 M. Angeles Serrano , Marian Boguna , Francesc Sagues

We introduce organism networks, which function like a single neural network but are composed of several neural particle networks; while each particle network fulfils the role of a single weight application within the organism network, it is…

Neural and Evolutionary Computing · Computer Science 2023-03-01 Steffen Illium , Maximilian Zorn , Cristian Lenta , Michael Kölle , Claudia Linnhoff-Popien , Thomas Gabor

Neural networks have seen an explosion of usage and research in the past decade, particularly within the domains of computer vision and natural language processing. However, only recently have advancements in neural networks yielded…

Machine Learning · Computer Science 2022-07-20 Jacob Renn , Ian Sotnek , Benjamin Harvey , Brian Caffo

During the first part of life, the brain develops while it learns through a process called synaptogenesis. The neurons, growing and interacting with each other, create synapses. However, eventually the brain prunes those synapses. While…

Neural and Evolutionary Computing · Computer Science 2023-04-04 Andrea Ferigo , Giovanni Iacca

Artificial neural networks which are inspired from the learning mechanism of brain have achieved great successes in many problems, especially those with deep layers. In this paper, we propose a nucleus neural network (NNN) and corresponding…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Jia Liu , Maoguo Gong , Haibo He

Most uses of machine learning today involve training a model from scratch for a particular task, or sometimes starting with a model pretrained on a related task and then fine-tuning on a downstream task. Both approaches offer limited…

Machine Learning · Computer Science 2022-05-26 Andrea Gesmundo , Jeff Dean
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