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Missing data is a fundamental challenge in data science, significantly hindering analysis and decision-making across a wide range of disciplines, including healthcare, bioinformatics, social science, e-commerce, and industrial monitoring.…

Machine Learning · Statistics 2026-05-12 Jicong Fan

Missing values are prevalent across various fields, posing challenges for training and deploying predictive models. In this context, imputation is a common practice, driven by the hope that accurate imputations will enhance predictions.…

Artificial Intelligence · Computer Science 2025-02-21 Marine Le Morvan , Gaël Varoquaux

We provide guidance on multiple imputation of missing at random treatments in observational studies. Specifically, analysts should account for both covariates and outcomes, i.e., not just use propensity scores, when imputing the missing…

Methodology · Statistics 2025-01-23 Joseph Feldman , Jerome P. Reiter

Inverse analysis, such as model calibration, often suffers from a lack of informative data in complex real-world scenarios. The standard remedy, designing new experimental setups, is often costly and time-consuming, while readily available…

Computational Engineering, Finance, and Science · Computer Science 2026-01-16 Lea J. Haeusel , Jonas Nitzler , Lea J. Köglmeier , Wolfgang A. Wall

Simulation studies are commonly used in methodological research for the empirical evaluation of data analysis methods. They generate artificial data sets under specified mechanisms and compare the performance of methods across conditions.…

Methodology · Statistics 2025-07-11 Samuel Pawel , František Bartoš , Björn S. Siepe , Anna Lohmann

While other fields such as statistics and education have examined various issues with quantitative work, few studies in physics education research (PER) have done so. We conducted a two-phase study to identify and to understand the extent…

Physics Education · Physics 2018-12-04 Alexis V. Knaub , John M. Aiken , Lin Ding

In this paper, we describe two paradigms in physics education research (PER): recurrence-oriented and case-oriented PER. We connect theory on research methodologies in the social sciences to interviews with physics education researchers and…

Physics Education · Physics 2018-01-15 Amy D. Robertson , Rachel E. Scherr , Sarah B. McKagan

Missing data imputation, where a model is trained on observed data to estimate unobserved values, is a fundamental problem in machine learning. In this paper, we rigorously formulate imputation model learning as a mean-squared error risk…

Machine Learning · Statistics 2026-05-14 Luke Shannon , Song Liu , Katarzyna Reluga

Multiple Imputation (MI) is one of the most popular approaches to addressing missing values in questionnaires and surveys. MI with multivariate imputation by chained equations (MICE) allows flexible imputation of many types of data. In…

Methodology · Statistics 2023-04-24 Edoardo Costantini , Kyle M. Lang , Klaas Sijtsma , Tim Reeskens

We introduce a novel approach to estimation problems in settings with missing data. Our proposal -- the Correlation-Assisted Missing data (CAM) estimator -- works by exploiting the relationship between the observations with missing features…

Methodology · Statistics 2020-03-02 Timothy I. Cannings , Yingying Fan

Methods for addressing missing data have become much more accessible to applied researchers. However, little guidance exists to help researchers systematically identify plausible missing data mechanisms in order to ensure that these methods…

Applications · Statistics 2020-07-29 Adam Davey , Ting Dai

Federated learning allows for the training of machine learning models on multiple decentralized local datasets without requiring explicit data exchange. However, data pre-processing, including strategies for handling missing data, remains a…

Machine Learning · Statistics 2023-04-18 Irene Balelli , Aude Sportisse , Francesco Cremonesi , Pierre-Alexandre Mattei , Marco Lorenzi

Uncertainty is an important and fundamental concept in physics education. Students are often first exposed to uncertainty in introductory labs, expand their knowledge across lab courses, and then are introduced to quantum mechanical…

Physics Education · Physics 2023-06-30 Andy Schang , Matthew Dew , Emily M. Stump , N. G. Holmes , Gina Passante

Missing data is a common concern in health datasets, and its impact on good decision-making processes is well documented. Our study's contribution is a methodology for tackling missing data problems using a combination of synthetic dataset…

Machine Learning · Computer Science 2022-11-08 Gift Khangamwa , Terence L. van Zyl , Clint J. van Alten

Item nonresponse is frequently encountered in practice. Ignoring missing data can lose efficiency and lead to misleading inference. Fractional imputation is a frequentist approach of imputation for handling missing data. However, the…

Methodology · Statistics 2018-09-18 Hejian Sang , Jae Kwang Kim

Multiple imputation is a popular method for handling missing data, with fully conditional specification (FCS) being one of the predominant imputation approaches for multivariable missingness. Unbiased estimation with standard…

Understanding whether and how treatment effects vary across subgroups is crucial to inform clinical practice and recommendations. Accordingly, the assessment of heterogeneous treatment effects (HTE) based on pre-specified potential effect…

Methodology · Statistics 2023-12-04 Bryan S. Blette , Scott D. Halpern , Fan Li , Michael O. Harhay

Missing data in online reinforcement learning (RL) poses challenges compared to missing data in standard tabular data or in offline policy learning. The need to impute and act at each time step means that imputation cannot be put off until…

Machine Learning · Statistics 2025-10-14 Kyla Chasalow , Skyler Wu , Susan Murphy

Predictive mean matching (PMM) is a popular imputation strategy that imputes missing values by borrowing observed values from other cases with similar expectations. We show that, unlike other imputation strategies, PMM is not guaranteed to…

Methodology · Statistics 2025-07-01 Paul T. von Hippel

Imputation methods for dealing with incomplete data typically assume that the missingness mechanism is at random (MAR). These methods can also be applied to missing not at random (MNAR) situations, where the user specifies some adjustment…

Methodology · Statistics 2024-04-24 Shahab Jolani , Stef van Buuren
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