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Stochastic computer simulations enable users to gain new insights into complex physical systems. Optimization is a common problem in this context: users seek to find model inputs that maximize the expected value of an objective function.…
We consider the effects of parameter uncertainty on the optimal radiation schedule in the context of the linear-quadratic model. Our interest arises from the observation that if inter-patient variations in OAR and tumor sensitivities to…
In sequential experiments, subjects become available for the study over a period of time, and covariates are often measured at the time of arrival. We consider the setting where the sample size is fixed but covariate values are unknown…
Limited English Proficiency (LEP) patients face higher risks of adverse health outcomes due to communication barriers, making timely medical interpreting services essential for mitigating those risks. This paper addresses the scheduling of…
We introduce a novel approach to reduce the computational effort of solving mixed-integer convex chance constrained programs through the scenario approach. Instead of reducing the number of required scenarios, we directly minimize the…
Patient scheduling is a difficult task involving stochastic factors such as the unknown arrival times of patients. Similarly, the scheduling of radiotherapy for cancer treatments needs to handle patients with different urgency levels when…
In this paper, an alternative count distribution suitable for modeling over dispersed, zero vertex unimodality and monotonically decreasing data sets. Though the proposed probability model includes Gauss Hypergeometric special function, it…
We propose a simulated annealing algorithm specifically tailored to optimise total retrieval times in a multi-level warehouse under complex pre-batched picking constraints. Experiments on real data from a picker-to-parts order picking…
In the context of uncertainty quantification, computational models are required to be repeatedly evaluated. This task is intractable for costly numerical models. Such a problem turns out to be even more severe for stochastic simulators, the…
In employing spatial regression models for counts, we usually meet two issues. First, ignoring the inherent collinearity between covariates and the spatial effect would lead to causal inferences. Second, real count data usually reveal over…
Stochastic programming can be applied to consider uncertainties in energy system optimization models for capacity expansion planning. However, these models become increasingly large and time-consuming to solve, even without considering…
Recently the patient-centered medical home (PCMH) model has become a popular team-based approach focused on delivering more streamlined care to patients. In current practices of medical homes, a clinical-based prediction frame is…
In this paper, we study a queueing model that incorporates patient reentrance to reflect patients' recurring requests for nurse care and their rest periods between these requests. Within this framework, we address two levels of…
Diagnostic clinics are among healthcare facilities that suffer from long waiting times which can cause medical issues and lead to increases in patient no-shows. Reducing waiting times without significant capital investments is a challenging…
Large-scale controlled evacuations require emergency services to select evacuation routes, decide departure times, and mobilize resources to issue orders, all under strict time constraints. Existing algorithms almost always allow for…
In this paper, we identify partial correlation information structures that allow for simpler reformulations in evaluating the maximum expected value of mixed integer linear programs with random objective coefficients. To this end, assuming…
Problem definition: Emergency department (ED) boarding refers to the practice of holding patients in the ED after they have been admitted to hospital wards, usually resulting from insufficient inpatient resources. Boarded patients may…
The distributed operating room (OR) scheduling problem aims to find an assignment of surgeries to ORs across collaborating hospitals that share their waiting lists and ORs. We propose a stochastic extension of this problem where surgery…
In a facility with front room and back room operations, it is useful to switch workers between the rooms in order to cope with changing customer demand. Assuming stochastic customer arrival and service times, we seek a policy for switching…
This paper addresses the problem of batching laboratory samples in hospital laboratories where samples of different priorities are received continuously with uncertain transportation times. The focus is on optimizing the control strategy…