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The Poisson-Boltzmann equation (PBE) is a nonlinear elliptic PDE that arises in biomolecular modeling and is a fundamental tool for structural biology. It is used to calculate electrostatic potentials around an ensemble of fixed charges…

Numerical Analysis · Mathematics 2017-10-12 Cleophas Kweyu , Lihong Feng , Matthias Stein , Peter Benner

The Poisson-Boltzmann equation (PBE) is a fundamental implicit solvent continuum model for calculating the electrostatic potential of large ionic solvated biomolecules. However, its numerical solution encounters severe challenges arising…

Numerical Analysis · Mathematics 2021-03-02 Cleophas Kweyu , Lihong Feng , Matthias Stein , Peter Benner

Parametric model order reduction using reduced basis methods can be an effective tool for obtaining quickly solvable reduced order models of parametrized partial differential equation problems. With speedups that can reach several orders of…

Numerical Analysis · Mathematics 2022-01-26 Mario Ohlberger , Stephan Rave

The Reduced Basis Method (RBM) is a rigorous model reduction approach for solving parametrized partial differential equations. It identifies a low-dimensional subspace for approximation of the parametric solution manifold that is embedded…

Numerical Analysis · Mathematics 2018-09-25 Yanlai Chen , Jiahua Jiang , Akil Narayan

Fractional Laplace equations are becoming important tools for mathematical modeling and prediction. Recent years have shown much progress in developing accurate and robust algorithms to numerically solve such problems, yet most solvers for…

Numerical Analysis · Mathematics 2018-08-03 Harbir Antil , Yanlai Chen , Akil Narayan

In recent years, reduced basis methods (RBMs) have been adapted to the many-body eigenvalue problem and they have been used, largely in nuclear physics, as fast emulators able to bypass expensive direct computations while still providing…

Superconductivity · Physics 2023-04-19 Virgil V. Baran , Denis R. Nichita

In this paper, we propose a certified reduced basis (RB) method for quasilinear elliptic problems together with its application to nonlinear magnetostatics equations, where the later model permanent magnet synchronous motors (PMSM). The…

Numerical Analysis · Mathematics 2020-07-03 Michael Hinze , Denis Korolev

The Reduced Basis (RB) method is a well established method for the model order reduction of problems formulated as parametrized partial differential equations. One crucial requirement for the application of RB schemes is the availability of…

Numerical Analysis · Mathematics 2016-11-25 Andreas Buhr , Christian Engwer , Mario Ohlberger , Stephan Rave

The Reduced Basis Method (RBM) is a model reduction technique used to solve parametric PDEs that relies upon a basis set of solutions to the PDE at specific parameter values. To generate this reduced basis, the set of a small number of…

Numerical Analysis · Mathematics 2018-03-05 Rachel Grotheer , Thilo Strauss , Phil Gralla , Taufiquar Khan

The Poisson-Boltzmann equation is widely used to model molecular electrostatics; however, it is usually solved in linearised form because the sinh nonlinearity is challenging, limiting its applicability in highly charged systems such as…

Computational Physics · Physics 2026-04-20 Mauricio Guerrero-Montero , Michal Bosy , Christopher D. Cooper

The Reduced Basis Method (RBM) is a popular certified model reduction approach for solving parametrized partial differential equations. One critical stage of the \textit{offline} portion of the algorithm is a greedy algorithm, requiring…

Numerical Analysis · Mathematics 2017-03-17 Jiahua Jiang , Yanlai Chen , Akil Narayan

The proximal bundle method (PBM) is a fundamental and computationally effective algorithm for solving nonsmooth optimization problems. In this paper, we present the first variant of the PBM for smooth objectives, achieving an accelerated…

Optimization and Control · Mathematics 2025-04-30 David Fersztand , Xu Andy Sun

The need for multiple interactive, real-time simulations using different parameter values has driven the design of fast numerical algorithms with certifiable accuracies. The reduced basis method (RBM) presents itself as such an option. RBM…

Numerical Analysis · Mathematics 2021-01-18 Yanlai Chen , Sigal Gottlieb , Lijie Ji , Yvon Maday

Probabilistic variants of Model Order Reduction (MOR) methods have recently emerged for improving stability and computational performance of classical approaches. In this paper, we propose a probabilistic Reduced Basis Method (RBM) for the…

Numerical Analysis · Mathematics 2023-12-06 Marie Billaud-Friess , Arthur Macherey , Anthony Nouy , Clémentine Prieur

A widely used electrostatics model in the biomolecular modeling community, the nonlinear Poisson-Boltzmann equation, along with its finite element approximation, are analyzed in this paper. A regularized Poisson-Boltzmann equation is…

Numerical Analysis · Mathematics 2010-01-12 Long Chen , Michael Holst , Jinchao Xu

Linear kinetic transport equations play a critical role in optical tomography, radiative transfer and neutron transport. The fundamental difficulty hampering their efficient and accurate numerical resolution lies in the high dimensionality…

Numerical Analysis · Mathematics 2021-12-07 Zhichao Peng , Yanlai Chen , Yingda Cheng , Fengyan Li

The task of repeatedly solving parametrized partial differential equations (pPDEs) in, e.g. optimization or interactive applications, makes it imperative to design highly efficient and equally accurate surrogate models. The reduced basis…

Numerical Analysis · Mathematics 2020-09-11 Yanlai Chen , Lijie Ji , Akil Narayan , Zhenli Xu

The radial basis function (RBF) method is used for the numerical solution of the Poisson problem in high dimension. The approximate solution can be found by solving a large system of linear equations. Here we investigate the extent to which…

Quantum Physics · Physics 2023-01-18 Lingxia Cui , Zongming Wu , Hua Xiang

A covariant energy density functional is calibrated using a principled Bayesian statistical framework informed by experimental binding energies and charge radii of several magic and semi-magic nuclei. The Bayesian sampling required for the…

Nuclear Theory · Physics 2022-09-28 Pablo Giuliani , Kyle Godbey , Edgard Bonilla , Frederi Viens , Jorge Piekarewicz

We present a class of reduced basis (RB) methods for the iterative solution of parametrized symmetric positive-definite (SPD) linear systems. The essential ingredients are a Galerkin projection of the underlying parametrized system onto a…

Numerical Analysis · Mathematics 2018-04-18 Ngoc-Cuong Nguyen , Yanlai Chen
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