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We propose a compartmental lateral inhibition system that generates contrasting patterns of gene expression between neighboring compartments. The system consists of a set of compartments interconnected by channels. Each compartment contains…

Dynamical Systems · Mathematics 2014-07-25 Ana Sofia Rufino Ferreira , Justin Hsia , Murat Arcak , Michel Maharbiz , Adam Arkin

Many patterning events in multi-cellular organisms rely on cell-to-cell contact signaling, such as the Notch pathway in metazoans. A particularly interesting phenomenon in this form of communication is lateral inhibition where a cell that…

Dynamical Systems · Mathematics 2012-01-09 Murat Arcak

During development, spatio-temporal patterns ranging from checkerboard to engulfing occur with precise proportions of the respective cell fates. Key developmental regulators are intracellular transcriptional interactions and intercellular…

Biological Physics · Physics 2022-11-15 Simon Schardt , Sabine C. Fischer

Fine-grain patterns produced by juxtacrine signalling, have been studied using static monolayers as cellular domains. Unfortunately, analytical results are restricted to a few cells due to the algebraic complexity of nonlinear dynamical…

Biological Physics · Physics 2021-05-26 Joshua W. Moore , Trevor C. Dale , Thomas E. Woolley

Coupled relaxation oscillators, realized via chemical or other means, can exhibit a multiplicity of steady states, characterized by spatial patterns resulting from lateral inhibition. We show that perturbation-initiated transformations…

Pattern Formation and Solitons · Physics 2023-06-22 A. Parveena Shamim , Shakti N. Menon , Sitabhra Sinha

In vivo and in vitro systems of cells and extra-cellular matrix (ECM) systems are well known to form ordered patterns of orientationally aligned fibers. Here, we interpret them as active analogs of the (disordered) isotropic to the…

Soft Condensed Matter · Physics 2025-04-11 Haiqian Yang , Ming Guo , L. Mahadevan

We study the inhibition of pattern formation in nonlinear optical systems using intracavity photonic crystals. We consider mean field models for single and doubly degenerate optical parametric oscillators. Analytical expressions for the new…

Pattern Formation and Solitons · Physics 2009-11-11 Damia Gomila , Gian-Luca Oppo

Oscillatory phase pattern formation and amplitude control for a linearized stochastic neuron field model was investigated by simulating coupled stochastic processes defined by stochastic differential equations. It was found, for several…

Neurons and Cognition · Quantitative Biology 2021-03-24 Conor L. Morrison , Priscilla E. Greenwood , Lawrence M. Ward

A novel robust mechanism for the generation of "trapping states" is shown to exist in the coupling of a two-level system with an oscillator, which is based on nonlinearities in the laser-induced vibronic coupling. This mechanism is…

Quantum Physics · Physics 2007-05-23 S. Wallentowitz , W. Vogel , P. E. Toschek

Phase diagram and pattern formation in two-dimensional Ising model with coupling between order parameter and lattice vibrations is investigated by Monte-Carlo simulations. It is shown that if the coupling is strong enough (or phonons are…

Statistical Mechanics · Physics 2011-11-10 I. K. Razumov , Yu. N. Gornostyrev , M. I. Katsnelson

In this paper we are interested in the prediction of preterm birth based on diagnosis codes from longitudinal EHR. We formulate the prediction problem as a supervised classification with noisy labels. Our base classifier is a Recurrent…

Machine Learning · Statistics 2018-12-07 Sabri Boughorbel , Fethi Jarray , Neethu Venugopal , Haithum Elhadi

Limit order books can transition rapidly from stable to stressed conditions, yet standard early-warning signals such as order flow imbalance and short-term volatility are inherently reactive. We formalise this limitation via a three-regime…

Machine Learning · Computer Science 2026-04-24 Prakul Sunil Hiremath , Vruksha Arun Hiremath

We show that the Hubbard Hamiltonian with particle-assisted tunneling rates --recently proposed to model a fermionic mixture near a broad Feshbach resonance-- displays a ground state phase diagram with superfluid, insulating, and phase…

Quantum Physics · Physics 2009-10-08 Alberto Anfossi , Luca Barbiero , Arianna Montorsi

The phase diagrams and transitions of nonequilibrium systems with multiplicative noise are studied theoretically. We show the existence of both strong and weak-coupling critical behavior, of two distinct active phases, and of a nonzero…

adap-org · Physics 2016-08-16 G. Grinstein , M. A. Muñoz , Yuhai Tu

The synchronous dynamics and the stationary states of a recurrent attractor neural network model with competing synapses between symmetric sequence processing and Hebbian pattern reconstruction is studied in this work allowing for the…

Disordered Systems and Neural Networks · Physics 2015-05-13 F. L. Metz , W. K. Theumann

We perform scanning gate experiments on ballistic constrictions in the presence of small perpendicular magnetic fields. The constrictions form the entrance and exit of a circular gate-defined ballistic stadium. Close to constrictions we…

Mesoscale and Nanoscale Physics · Physics 2015-06-15 A. A. Kozikov , D. Weinmann , C. Roessler , T. Ihn , K. Ensslin , C. Reichl , W. Wegscheider

We propose a data-analytic method for detecting cellwise outliers. Given a robust covariance matrix, outlying cells (entries) in a row are found by the cellHandler technique which combines lasso regression with a stepwise application of…

Methodology · Statistics 2024-07-08 Jakob Raymaekers , Peter J. Rousseeuw

The paper shows that positive linear systems can be stabilized using positive Luenberger-type observers. This is achieved by structuring the observer as monotonically converging upper and lower bounds on the state. Analysis of the…

Optimization and Control · Mathematics 2026-04-21 David Ohlin , Anders Rantzer , Emma Tegling

Pedestrian dynamics exhibits various collective phenomena. Here we study bidirectional pedestrian flow in a floor field cellular automaton model. Under certain conditions, lane formation is observed. Although it has often been studied…

Physics and Society · Physics 2012-07-25 Stefan Nowak , Andreas Schadschneider

For cellular biochemical reaction systems where the numbers of molecules is small, significant noise is associated with chemical reaction events. This molecular noise can give rise to behavior that is very different from the predictions of…

Molecular Networks · Quantitative Biology 2009-11-13 Matthew Scott , Terence Hwa , Brian Ingalls
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