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Accurately modeling and designing protein complex structures is a central problem in computational structural biology, with broad implications for understanding cellular function and developing therapeutics. This thesis investigates two…

Machine Learning · Computer Science 2026-05-13 Ziwei Xie

Deep Learning (DL) is a surprisingly successful branch of machine learning. The success of DL is usually explained by focusing analysis on a particular recent algorithm and its traits. Instead, we propose that an explanation of the success…

Machine Learning · Computer Science 2022-05-23 Artem Kaznatcheev , Konrad Paul Kording

Neural networks extract features from data using stochastic gradient descent (SGD). In particular, higher-order input cumulants (HOCs) are crucial for their performance. However, extracting information from the $p$th cumulant of…

Machine Learning · Statistics 2024-10-16 Lorenzo Bardone , Sebastian Goldt

Deep neural networks implement a sequence of layer-by-layer operations that are each relatively easy to understand, but the resulting overall computation is generally difficult to understand. We consider a simple hypothesis for interpreting…

Machine Learning · Computer Science 2022-11-29 Richard D. Lange , Devin Kwok , Jordan Matelsky , Xinyue Wang , David S. Rolnick , Konrad P. Kording

Machine Learning algorithms have had a profound impact on the field of computer science over the past few decades. These algorithms performance is greatly influenced by the representations that are derived from the data in the learning…

Automated detection of software vulnerabilities is a fundamental problem in software security. Existing program analysis techniques either suffer from high false positives or false negatives. Recent progress in Deep Learning (DL) has…

Software Engineering · Computer Science 2020-09-16 Saikat Chakraborty , Rahul Krishna , Yangruibo Ding , Baishakhi Ray

Deep learning involves navigating a high-dimensional loss landscape over the neural network parameter space. Over the course of training, complex computational structures form and re-form inside the neural network, leading to shifts in…

Machine Learning · Computer Science 2025-08-04 Jesse Hoogland , George Wang , Matthew Farrugia-Roberts , Liam Carroll , Susan Wei , Daniel Murfet

Deep neural networks have proved to be a very effective way to perform classification tasks. They excel when the input data is high dimensional, the relationship between the input and the output is complicated, and the number of labeled…

Machine Learning · Computer Science 2017-11-28 Nicholas Frosst , Geoffrey Hinton

Topological learning is a wide research area aiming at uncovering the mutual spatial relationships between the elements of a set. Some of the most common and oldest approaches involve the use of unsupervised competitive neural networks.…

Machine Learning · Statistics 2021-11-03 Pietro Barbiero , Gabriele Ciravegna , Vincenzo Randazzo , Giansalvo Cirrincione

Convolutional Neural Network (CNN) has gained state-of-the-art results in many pattern recognition and computer vision tasks. However, most of the CNN structures are manually designed by experienced researchers. Therefore, auto- matically…

Neural and Evolutionary Computing · Computer Science 2018-10-26 Guoqiang Zhong , Tao Li , Wenxue Liu , Yang Chen

Differentiable programming is the combination of classical neural networks modules with algorithmic ones in an end-to-end differentiable model. These new models, that use automatic differentiation to calculate gradients, have new learning…

Dynamical Systems · Mathematics 2020-05-05 Adrián Hernández , José M. Amigó

Deep learning uses neural networks which are parameterised by their weights. The neural networks are usually trained by tuning the weights to directly minimise a given loss function. In this paper we propose to re-parameterise the weights…

Neural and Evolutionary Computing · Computer Science 2022-03-14 Michael Fairbank , Spyridon Samothrakis , Luca Citi

As the number of cyber-attacks is increasing, cybersecurity is evolving to a key concern for any business. Artificial Intelligence (AI) and Machine Learning (ML) (in particular Deep Learning - DL) can be leveraged as key enabling…

Cryptography and Security · Computer Science 2020-12-08 Mayra Macas , Chunming Wu

We present an architecture which lets us train deep, directed generative models with many layers of latent variables. We include deterministic paths between all latent variables and the generated output, and provide a richer set of…

Machine Learning · Computer Science 2016-12-15 Philip Bachman

Discriminative features play an important role in image and object classification and also in other fields of research such as semi-supervised learning, fine-grained classification, out of distribution detection. Inspired by Linear…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Mai Lan Ha , Gianni Franchi , Emanuel Aldea , Volker Blanz

It is argued that deep learning is efficient for data that is generated from hierarchal generative models. Examples of such generative models include wavelet scattering networks, functions of compositional structure, and deep rendering…

Machine Learning · Computer Science 2018-09-06 Elchanan Mossel

Originally designed for applications in computer graphics, visual computing (VC) methods synthesize information about physical and virtual worlds, using prescribed algorithms optimized for spatial computing. VC is used to analyze geometry,…

Large language models (LLM) are advanced AI systems trained on extensive textual data, leveraging deep learning techniques to understand and generate human-like language. Today's LLMs with billions of parameters are so huge that hardly any…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-14 Sheikh Azizul Hakim , Saem Hasan

Deep learning is usually described as an experiment-driven field under continuous criticizes of lacking theoretical foundations. This problem has been partially fixed by a large volume of literature which has so far not been well organized.…

Machine Learning · Computer Science 2021-03-12 Fengxiang He , Dacheng Tao

Deep learning (DL) research yields accuracy and product improvements from both model architecture changes and scale: larger data sets and models, and more computation. For hardware design, it is difficult to predict DL model changes.…

Machine Learning · Computer Science 2019-09-05 Joel Hestness , Newsha Ardalani , Greg Diamos
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