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As a generalization of the optimal mass transport (OMT) approach of Benamou and Brenier's, the regularized optimal mass transport (rOMT) formulates a transport problem from an initial mass configuration to another with the optimality…

Numerical Analysis · Mathematics 2023-09-22 Xinan Chen , Helene Benveniste , Allen R. Tannenbaum

Generative Design (GD) combines artificial intelligence (AI), physics-based modeling, and multi-objective optimization to autonomously explore and refine engineering designs. Despite its promise in aerospace, automotive, and other…

Computational Engineering, Finance, and Science · Computer Science 2025-11-24 Sergio Torregrosa , David Munoz , Hector Navarro , Charbel Farhat , Francisco Chinesta

In medical image visualization, path tracing of volumetric medical data like CT scans produces lifelike three-dimensional visualizations. Immersive VR displays can further enhance the understanding of complex anatomies. Going beyond the…

Graphics · Computer Science 2026-01-30 Constantin Kleinbeck , Hannah Schieber , Klaus Engel , Ralf Gutjahr , Daniel Roth

Histopathology is critical for the diagnosis of many diseases, including cancer. These protocols typically require pathologists to manually evaluate slides under a microscope, which is time-consuming and subjective, leading to interest in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Kianoush Falahkheirkhah , Alex Lu , David Alvarez-Melis , Grace Huynh

Continuous normalizing flows (CNFs) construct invertible mappings between an arbitrary complex distribution and an isotropic Gaussian distribution using Neural Ordinary Differential Equations (neural ODEs). It has not been tractable on…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Shian Du , Yihong Luo , Wei Chen , Jian Xu , Delu Zeng

Optical Chemical Structure Recognition (OCSR) is essential for converting molecular images into machine-readable formats. While recent vision-language models (VLMs) have shown promise, their image-captioning approach often struggles with…

Artificial Intelligence · Computer Science 2026-01-14 Jingchao Wang , Yifan He , Haote Yang , Jiang Wu , Lingli Ge , Xingjian Wei , Yinfan Wang , Linye Li , Huijie Ao , Chengjin Liu , Bin Wang , Lijun Wu , Conghui He

We present a novel framework based on optimal transport for the challenging problem of comparing graphs. Specifically, we exploit the probabilistic distribution of smooth graph signals defined with respect to the graph topology. This allows…

Machine Learning · Computer Science 2019-12-09 Hermina Petric Maretic , Mireille EL Gheche , Giovanni Chierchia , Pascal Frossard

Optimal transport (OT) and Gromov-Wasserstein (GW) alignment are powerful frameworks for geometrically driven matching of probability distributions, yet their large-scale usage is hampered by high statistical and computational costs.…

Statistics Theory · Mathematics 2026-02-04 Tao Wang , Ziv Goldfeld

The objective in statistical Optimal Transport (OT) is to consistently estimate the optimal transport plan/map solely using samples from the given source and target marginal distributions. This work takes the novel approach of posing…

Machine Learning · Computer Science 2020-11-11 J. Saketha Nath , Pratik Jawanpuria

Generating computational anatomical models of cerebrovascular networks is vital for improving clinical practice and understanding brain oxygen transport. This is achieved by extracting graph-based representations based on pre-mapping of…

Quantitative Methods · Quantitative Biology 2019-12-23 Rafat Damseh , Patrick Delafontaine-Martel , Philippe Pouliot , Farida Cheriet , Frederic Lesage

Mass transport problems arise in many areas of machine learning whereby one wants to compute a map transporting one distribution to another. Generative modeling techniques like Generative Adversarial Networks (GANs) and Denoising Diffusion…

Machine Learning · Computer Science 2024-09-17 Valentin De Bortoli , Iryna Korshunova , Andriy Mnih , Arnaud Doucet

Optimal Transport (OT) has recently emerged as a central tool in data sciences to compare in a geometrically faithful way point clouds and more generally probability distributions. The wide adoption of OT into existing data analysis and…

Machine Learning · Statistics 2023-01-18 Thibault Séjourné , Gabriel Peyré , François-Xavier Vialard

In this paper, we propose image restoration models using optimal transport (OT) and total variation regularization. We present theoretical results of the proposed models based on the relations between the dual Lipschitz norm from OT and the…

Numerical Analysis · Mathematics 2025-03-20 Weijia Huang , Zhongyi Huang , Wenli Yang , Wei Zhu

We address the convergence problem in learning the Optimal Transport (OT) map, where the OT Map refers to a map from one distribution to another while minimizing the transport cost. Semi-dual Neural OT, a widely used approach for learning…

Machine Learning · Computer Science 2026-02-03 Jaemoo Choi , Jaewoong Choi , Dohyun Kwon

In classification tasks, it is crucial to meaningfully exploit the information contained in data. While much of the work in addressing these tasks is devoted to building complex algorithmic infrastructures to process inputs in a black-box…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Alessandro Lonardi , Diego Baptista , Caterina De Bacco

Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Xuanzhao Dong , Wenhui Zhu , Xin Li , Guoxin Sun , Yi Su , Oana M. Dumitrascu , Yalin Wang

The performance of flow matching and diffusion models can be greatly improved at inference time using reward alignment algorithms, yet efficiency remains a major limitation. While several algorithms were proposed, we demonstrate that a…

Machine Learning · Computer Science 2026-02-12 Peter Holderrieth , Uriel Singer , Tommi Jaakkola , Ricky T. Q. Chen , Yaron Lipman , Brian Karrer

Effectively modeling multimodal spatial omics data is critical for understanding tissue complexity and underlying biological mechanisms. While spatial transcriptomics, proteomics, and epigenomics capture molecular features, they lack…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Yongjun Xiao , Dian Meng , Xinlei Huang , Yanran Liu , Shiwei Ruan , Ziyue Qiao , Xubin Zheng

Recent Alzheimer's disease (AD) patient studies have focused on retinal analysis, as the retina is the only part of the central nervous system which can be imaged non-invasively by optical methods. However as this is a relatively new…

Following [21, 23], the present work investigates a new relative entropy-regularized algorithm for solving the optimal transport on a graph problem within the randomized shortest paths formalism. More precisely, a unit flow is injected into…

Machine Learning · Computer Science 2021-09-21 Sylvain Courtain , Guillaume Guex , Ilkka Kivimaki , Marco Saerens