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Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

Methodology · Statistics 2022-08-30 Max Westphal , Antonia Zapf

Computational protein-protein interaction (PPI) prediction techniques can contribute greatly in reducing time, cost and false-positive interactions compared to experimental approaches. Sequence is one of the key and primary information of…

Machine Learning · Computer Science 2022-03-29 Soumyadeep Debnath , Ayatullah Faruk Mollah

In this work we propose tracking as a generic addition to the instance search task. From video data perspective, much information that can be used is not taken into account in the traditional instance search approach. This work aims to…

Information Retrieval · Computer Science 2018-03-02 Andreu Girbau , Ryota Hinami , Shin'ichi Satoh

Goal Recognition is the task by which an observer aims to discern the goals that correspond to plans that comply with the perceived behavior of subject agents given as a sequence of observations. Research on Goal Recognition as Planning…

Artificial Intelligence · Computer Science 2024-04-12 Felipe Meneguzzi , Luísa R. de A. Santos , Ramon Fraga Pereira , André G. Pereira

With the rapid advancement of information technology, the complexity of applications continues to increase, and the cybersecurity challenges we face are also escalating. This paper aims to investigate the methods and practices of system…

Cryptography and Security · Computer Science 2026-02-02 Chunyi Zhang , Jin Zeng , Xiaoqi Li

Test-time compute has led to remarkable success in the large language model (LLM) community, particularly for complex tasks, where longer chains of thought (CoTs) are generated to enhance reasoning capabilities. However, growing evidence…

Artificial Intelligence · Computer Science 2025-10-23 Chenxu Yang , Qingyi Si , Mz Dai , Dingyu Yao , Mingyu Zheng , Minghui Chen , Zheng Lin , Weiping Wang

The identification of compound-protein interactions (CPI) plays a critical role in drug screening, drug repurposing, and combination therapy studies. The effectiveness of CPI prediction relies heavily on the features extracted from both…

Biomolecules · Quantitative Biology 2023-06-16 Li Zhang , Wenhao Li , Haotian Guan , Zhiquan He , Mingjun Cheng , Han Wang

Refinement types are a well-studied manner of performing in-depth analysis on functional programs. The dependency pair method is a very powerful method used to prove termination of rewrite systems; however its extension to higher order…

Logic in Computer Science · Computer Science 2011-01-25 Cody Roux

Current approaches for points-of-interest (POI) recommendation learn the preferences of a user via the standard spatial features such as the POI coordinates, the social network, etc. These models ignore a crucial aspect of spatial mobility…

Machine Learning · Computer Science 2022-09-20 Vinayak Gupta , Srikanta Bedathur

The continuous net reclassification improvement (NRI) statistic is a popular model change measure that was developed to assess the incremental value of new factors in a risk prediction model. Two prominent statistical issues identified in…

Methodology · Statistics 2022-04-08 Glenn Heller

The biastest command in Stata is a powerful and user-friendly tool designed to compare the coefficients of different regression models, enabling researchers to assess the robustness and consistency of their empirical findings. This command…

Econometrics · Economics 2025-06-19 Hasraddin Guliyev

This paper calls attention to the missing component of the recommender system evaluation process: Statistical Inference. There is active research in several components of the recommender system evaluation process: selecting baselines,…

Information Retrieval · Computer Science 2021-09-15 Ngozi Ihemelandu , Michael D. Ekstrand

Text de-identification techniques are often used to mask personally identifiable information (PII) from documents. Their ability to conceal the identity of the individuals mentioned in a text is, however, hard to measure. Recent work has…

Computation and Language · Computer Science 2025-10-13 Lucas Georges Gabriel Charpentier , Pierre Lison

Testing has become an indispensable activity of software development, yet writing good and relevant tests remains a quite challenging task. One well-known problem is that it often is impossible or unrealistic to test for every outcome, as…

Programming Languages · Computer Science 2017-08-18 Dimitri Racordon , Didier Buchs

Proofs of Concept (PoCs) are widely adopted practices in software engineering. Despite their relevance, PoCs remain conceptually underdefined and methodologically ad hoc in both research and industry, with definitions and implementation…

Software Engineering · Computer Science 2026-04-08 Bruno Fernando Antognolli , Fabio Petrillo

Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing…

Machine Learning · Computer Science 2023-04-12 Zifeng Wang , Cao Xiao , Jimeng Sun

Principal component analysis (PCA) is often used for analyzing data in the most diverse areas. In this work, we report an integrated approach to several theoretical and practical aspects of PCA. We start by providing, in an intuitive and…

Computational Engineering, Finance, and Science · Computer Science 2021-06-09 Felipe L. Gewers , Gustavo R. Ferreira , Henrique F. de Arruda , Filipi N. Silva , Cesar H. Comin , Diego R. Amancio , Luciano da F. Costa

Widely used methods and software for group sequential tests of a null hypothesis of no treatment difference that allow for early stopping of a clinical trial depend primarily on the fact that sequentially-computed test statistics have the…

Methodology · Statistics 2025-06-19 Anastasios A. Tsiatis , Marie Davidian

Static analysis techniques enhance the security, performance, and reliability of programs by analyzing and portraiting program behaviors without the need for actual execution. In essence, static analysis takes the Intermediate…

Programming Languages · Computer Science 2024-05-22 Bowen Zhang , Wei Chen , Hung-Chun Chiu , Charles Zhang

The class of direct preference optimization (DPO) algorithms has emerged as a promising approach for solving the alignment problem in foundation models. These algorithms work with very limited feedback in the form of pairwise preferences…

Machine Learning · Computer Science 2026-02-03 Luca Viano , Ruida Zhou , Yifan Sun , Mahdi Namazifar , Volkan Cevher , Shoham Sabach , Mohammad Ghavamzadeh
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