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The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…

Optimization and Control · Mathematics 2014-01-30 Helena Sofia Rodrigues

We propose and analyze a nonlinear age-structured multi-species model that serves as a unifying framework for ecological and biotechnological systems in complex environments (microbial communities, bioreactors, and others). The formulation…

Analysis of PDEs · Mathematics 2025-09-23 Marius Bargo , Yacouba Simpore

Wolbachia infection in Anopheles albimanus mosquitoes can render mosquitoes less capable of spreading malaria. We develop and analyze an ordinary differential equation model to evaluate the effectiveness of Wolbachia-based vector control…

Populations and Evolution · Quantitative Biology 2023-03-10 Daniela Florez , Alyssa Young , Kerlly J. Bernabe , James M. Hyman , Zhuolin Qu

Background Elimination of malaria can only be achieved through removal of all vectors or complete depletion of the infectious reservoir in humans. Mechanistic models can be built to synthesize diverse observations from the field collected…

Populations and Evolution · Quantitative Biology 2015-07-13 Jaline Gerardin , Andre Lin Ouedraogo , Kevin A. McCarthy , Bocar Kouyate , Philip A. Eckhoff , Edward A. Wenger

In this paper we propose a malaria within-host model with k classes of age for the parasitized red blood cells and n strains for the parasite. We provide a global analysis for this model. A competitive exclusion principle holds. If R0, the…

Dynamical Systems · Mathematics 2011-01-06 Abderrahman Iggidr , Jean-Claude Kamgang , Gauthier Sallet , Jean-Jules Tewa

Dengue is one of the major international public health concerns. Although progress is underway, developing a vaccine against the disease is challenging. Thus, the main approach to fight the disease is vector control. A model for the…

Optimization and Control · Mathematics 2015-03-19 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres , Alan Zinober

Studies in malaria control cover many areas such as medicine, sociology, biology, mathematic, physic, computer science and so forth. Researches in the realm of mathematic are conducted to predict the occurrence of the disease and to support…

Populations and Evolution · Quantitative Biology 2020-04-15 Lynda Bouzid Khiri , Ibrahima Gueye , Hubert Naacke , Idrissa Sarr , Stéphane Gançarski

The model considers the human population, the adult mosquito population and the population of immature stages, which includes eggs, larvae and pupae. The model also considers the vertical transmission of dengue in the mosquitoes and the…

Mosquitoes are a major vector for malaria, causing hundreds of thousands of deaths in the developing world each year. Not only is the prevention of mosquito bites of paramount importance to the reduction of malaria transmission cases, but…

Machine Learning · Statistics 2017-12-07 Yunpeng Li , Davide Zilli , Henry Chan , Ivan Kiskin , Marianne Sinka , Stephen Roberts , Kathy Willis

Rabies remains a pressing global public health issue, demanding effective modeling and control strategies. This study focused on developing a mathematical model using ordinary differential equations (ODEs) to estimate parameters and assess…

Populations and Evolution · Quantitative Biology 2024-10-22 Mfano Charles , Sayoki G. Mfinanga , G. A. Lyakurwa , Delfim F. M. Torres , Verdiana G. Masanja

Malaria is a serious global health problem which is especially devastating to the developing world. Mosquitoes are the carriers of the parasite responsible for the disease, and hence malaria control programs focus on controlling mosquito…

Dynamical Systems · Mathematics 2016-06-17 Bhushan Kotnis , Joy Kuri

In this work we analyze mathematically the consequences and effectiveness of strategies to control an epidemic in the framework of classical SEIR models with multiple parallel infectious stages. We define the mathematical concept of a…

Dynamical Systems · Mathematics 2023-08-17 Annibal Figueiredo , Tarcısio Marciano da Rocha Filho

We propose a compartmental model for vector-transmitted diseases, such as Malaria and Dengue, spreading over complex networks. Individuals are represented by independent random walkers and vectors by infected nodes. Both walkers and nodes…

Populations and Evolution · Quantitative Biology 2025-05-05 Téo Granger , Thomas M. Michelitsch , Bernard A. Collet , Michael Bestehorn , Alejandro P. Riascos

In mathematical epidemiology, epidemic control often aims at driving the number of infected individuals to zero, asymptotically. However , during the transitory phase, the number of infected can peak at high values. In this paper, we…

Optimization and Control · Mathematics 2015-10-06 Michel De Lara , Lilian Sofia Sepulveda Salcedo

Aedes aegypti is known as the responsible vector transmitting dengue flavivirus. Unavailability of medication to cure the transmission of the virus in the human blood becomes a global health issue in recent decades. World epidemiologists…

Populations and Evolution · Quantitative Biology 2017-12-04 Karunia Putra Wijaya , Thomas Goetz , Edy Soewono

Mosquito-borne diseases remain a major public-health threat, and the effective control of mosquito populations requires sustained household participation in removing breeding sites. While environmental drivers of mosquito oscillations have…

Dynamical Systems · Mathematics 2026-01-09 Mohammad Rubayet Rahman , Chanaka Kottegoda , Lucas M. Stolerman

During the last decades, the global prevalence of dengue progressed dramatically. It is a disease which is now endemic in more than one hundred countries of Africa, America, Asia and the Western Pacific. This study addresses a mathematical…

This study examines the behavior of solutions in a multi-patch epidemic model that includes a saturation incidence mechanism. When the fatality rate due to the disease is not null, our findings show that the solutions of the model tend to…

Populations and Evolution · Quantitative Biology 2024-09-19 Yawo Ezunkpe , Cynthia T. Nnolum , Rachidi B. Salako , Shuwen Xue

Treatment of stagnant water bodies that act as a breeding site for malarial vectors is a fundamental step in most malaria elimination campaigns. However, identification of such water bodies over large areas is expensive, labour-intensive…

Machine Learning · Computer Science 2024-07-17 Aishwarya Jadhav

In this paper, we propose a sex-structured entomological model that serves as a basis for design of control strategies relying on releases of sterile male mosquitoes (Aedes spp) and aiming at elimination of the wild vector population in…

Optimization and Control · Mathematics 2020-10-02 Pierre-Alexandre Bliman , Daiver Cardona-Salgado , Yves Dumont , Olga Vasilieva