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Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

Randomized clinical trials eliminate confounding but impose strict exclusion criteria that limit recruitment to a subset of the population. Observational datasets are more inclusive but suffer from confounding -- often providing overly…

Machine Learning · Statistics 2022-10-31 Eric V. Strobl , Thomas A. Lasko

A new approach to clustering, based on the physical properties of inhomogeneous coupled chaotic maps, is presented. A chaotic map is assigned to each data-point and short range couplings are introduced. The stationary regime of the system…

Statistical Mechanics · Physics 2009-10-31 L. Angelini , F. De Carlo , C. Marangi , M. Pellicoro , S. Stramaglia

Early identification of patients at risk for clinical deterioration in the intensive care unit (ICU) remains a critical challenge. Delayed recognition of impending adverse events, including mortality, vasopressor initiation, and mechanical…

Machine Learning · Computer Science 2026-03-17 Binesh Sadanandan

Background: Clinical trials are designed to prove the efficacy of an intervention by means of model-based approaches involving parametric hypothesis testing. Issues arise when no effect is observed in the study population. Indeed, an effect…

There has been much recent research on human activity re\-cog\-ni\-tion (HAR), due to the proliferation of wearable sensors in watches and phones, and the advances of deep learning methods, which avoid the need to manually extract features…

Machine Learning · Computer Science 2022-09-20 Louis Mahon , Thomas Lukasiewicz

Clustering partitions a dataset such that observations placed together in a group are similar but different from those in other groups. Hierarchical and $K$-means clustering are two approaches but have different strengths and weaknesses.…

Machine Learning · Statistics 2017-12-27 Anna D. Peterson , Arka P. Ghosh , Ranjan Maitra

Datasets with a mixture of numerical and categorical attributes are routinely encountered in many application domains. In this work we examine an approach to clustering such datasets using homogeneity analysis. Homogeneity analysis…

Machine Learning · Statistics 2017-10-31 Rajiv Sambasivan , Sourish Das

$\kC$ clustering is a fundamental classification problem, where the task is to categorize the given collection of entities into $k$ clusters and come up with a representative for each cluster, so that the maximum distance between an entity…

Data Structures and Algorithms · Computer Science 2025-03-04 Farehe Soheil , Kirill Simonov , Tobias Friedrich

Opioid overdose rates have reached an epidemic level and state-level policy innovations have followed suit in an effort to prevent overdose deaths. State-level drug law is a set of policies that may reinforce or undermine each other, and…

Applications · Statistics 2020-10-07 Jarrod Olson , Po-Hsu Allen Chen , Marissa White , Nicole Brennan , Ning Gong

Clustering algorithms are often used to find subpopulations in exploratory data analysis workflows. Not only the clusters themselves, but also their shape can represent meaningful subpopulations. In this paper, we present FLASC, an…

Machine Learning · Computer Science 2025-04-23 D. M. Bot , J. Peeters , J. Liesenborgs , J. Aerts

Clustering has long been a popular unsupervised learning approach to identify groups of similar objects and discover patterns from unlabeled data in many applications. Yet, coming up with meaningful interpretations of the estimated clusters…

Methodology · Statistics 2020-05-26 Minjie Wang , Tianyi Yao , Genevera I. Allen

Clustering is an essential data mining tool that aims to discover inherent cluster structure in data. For most applications, applying clustering is only appropriate when cluster structure is present. As such, the study of clusterability,…

Machine Learning · Statistics 2018-10-30 A. Adolfsson , M. Ackerman , N. C. Brownstein

With the increasing interest in deploying Artificial Intelligence in medicine, we previously introduced HAIM (Holistic AI in Medicine), a framework that fuses multimodal data to solve downstream clinical tasks. However, HAIM uses data in a…

Artificial Intelligence · Computer Science 2025-07-02 Periklis Petridis , Georgios Margaritis , Vasiliki Stoumpou , Dimitris Bertsimas

Multimodal clustering is an unsupervised technique for mining interesting patterns in $n$-adic binary relations or $n$-mode networks. Among different types of such generalized patterns one can find biclusters and formal concepts (maximal…

Social and Information Networks · Computer Science 2017-03-01 Dmitry I. Ignatov , Alexander Semenov , Daria Komissarova , Dmitry V. Gnatyshak

Exploring large-scale text corpora presents a significant challenge in biomedical, finance, and legal domains, where vast amounts of documents are continuously published. Traditional search methods, such as keyword-based search, often…

Computation and Language · Computer Science 2025-06-18 Ashish Chouhan , Saifeldin Mandour , Michael Gertz

Objective: The aim of this research is to demonstrate how the use of hierarchical cluster analysis on 366 municipalities and other minor entities (parishes) of Venezuela, could be useful to consider regional differences and similarities…

Choosing appropriate hyperparameters for unsupervised clustering algorithms in an optimal way depending on the problem under study is a long standing challenge, which we tackle while adapting clustering algorithms for immune disorder…

Quantitative Methods · Quantitative Biology 2020-09-25 A. Carpio , A. Simón , L. F. Villa

The preclinical stage of many neurodegenerative diseases can span decades before symptoms become apparent. Understanding the sequence of preclinical biomarker changes provides a critical opportunity for early diagnosis and effective…

Methodology · Statistics 2024-06-11 Yizhen Xu , Scott Zeger , Zheyu Wang

Estimation of heterogeneous treatment effects is an active area of research. Most of the existing methods, however, focus on estimating the conditional average treatment effects of a single, binary treatment given a set of pre-treatment…

Methodology · Statistics 2025-05-30 Max Goplerud , Kosuke Imai , Nicole E. Pashley