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Segmentation and accurate localization of nuclei in histopathological images is a very challenging problem, with most existing approaches adopting a supervised strategy. These methods usually rely on manual annotations that require a lot of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Mihir Sahasrabudhe , Stergios Christodoulidis , Roberto Salgado , Stefan Michiels , Sherene Loi , Fabrice André , Nikos Paragios , Maria Vakalopoulou

We evaluated the temporal performance of a deep learning (DL) based artificial intelligence (AI) model for auto segmentation in prostate radiotherapy, seeking to correlate its efficacy with changes in clinical landscapes. Our study involved…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Biling Wang , Michael Dohopolski , Ti Bai , Junjie Wu , Raquibul Hannan , Neil Desai , Aurelie Garant , Daniel Yang , Dan Nguyen , Mu-Han Lin , Robert Timmerman , Xinlei Wang , Steve Jiang

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

Background and purpose: Colorectal cancer has become the third most common cancer worldwide, accounting for approximately 10% of cancer patients. Early detection of the disease is important for the treatment of colorectal cancer patients.…

Image and Video Processing · Electrical Eng. & Systems 2022-02-18 Weiming Hu , Chen Li , Xiaoyan Li , Md Mamunur Rahaman , Yong Zhang , Haoyuan Chen , Wanli Liu , Yudong Yao , Hongzan Sun , Ning Xu , Xinyu Huang , Marcin Grzegorze

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

Prostate segmentation from magnetic resonance imaging (MRI) is a challenging task. In recent years, several network architectures have been proposed to automate this process and alleviate the burden of manual annotation. Although the…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Dimitrios G. Zaridis , Eugenia Mylona , Nikolaos S. Tachos , Kostas Marias , Nikolaos Papanikolaou , Manolis Tsiknakis , Dimitrios I. Fotiadis

Automatic segmentation of skin lesion is considered a crucial step in Computer Aided Diagnosis (CAD) for melanoma diagnosis. Despite its significance, skin lesion segmentation remains a challenging task due to their diverse color, texture,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-27 Md. Kamrul Hasan , Lavsen Dahal , Prasad N. Samarakoon , Fakrul Islam Tushar , Robert Marti Marly

Radiologists often mix medical image reading strategies, including inspection of individual modalities and local image regions, using information at different locations from different images independently as well as concurrently. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Xiangcen Wu , Shaheer U. Saeed , Yipei Wang , Ester Bonmati Coll , Yipeng Hu

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Philipp Kainz , Michael Pfeiffer , Martin Urschler

Recent advances in medical imaging techniques have led to significant improvements in the management of prostate cancer (PCa). In particular, multi-parametric MRI (mp-MRI) continues to gain clinical acceptance as the preferred imaging…

Image and Video Processing · Electrical Eng. & Systems 2019-10-08 Ruiming Cao , Xinran Zhong , Fabien Scalzo , Steven Raman , Kyung hyun Sung

Automatic cell segmentation is an essential step in the pipeline of computer-aided diagnosis (CAD), such as the detection and grading of breast cancer. Accurate segmentation of cells can not only assist the pathologists to make a more…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Muyi Sun , Zeyi Yao , Guanhong Zhang

Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown…

Image and Video Processing · Electrical Eng. & Systems 2019-12-05 Naofumi Tomita , Behnaz Abdollahi , Jason Wei , Bing Ren , Arief Suriawinata , Saeed Hassanpour

Prostate cancer is the most dangerous cancer diagnosed in men worldwide. Prostate diagnosis has been affected by many factors, such as lesion complexity, observer visibility, and variability. Many techniques based on Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hussein Hashem , Yasmin Alsakar , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Developing an AI-assisted gland segmentation method from histology images is critical for automatic cancer diagnosis and prognosis; however, the high cost of pixel-level annotations hinders its applications to broader diseases. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Yi Li , Yiduo Yu , Yiwen Zou , Tianqi Xiang , Xiaomeng Li

This paper summarizes the method used in our submission to Task 1 of the International Skin Imaging Collaboration's (ISIC) Skin Lesion Analysis Towards Melanoma Detection challenge held in 2018. We used a fully automated method to…

Computer Vision and Pattern Recognition · Computer Science 2018-07-16 Joshua Peter Ebenezer , Jagath C. Rajapakse

Virtual immunohistochemistry (IHC) staining from hematoxylin and eosin (H&E) images can accelerate diagnostics by providing preliminary molecular insight directly from routine sections, reducing the need for repeat sectioning when tissue is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Jillur Rahman Saurav , Thuong Le Hoai Pham , Pritam Mukherjee , Paul Yi , Brent A. Orr , Jacob M. Luber

Cervical cancer remains a significant global health concern and a leading cause of cancer-related deaths among women. Early detection through Pap smear tests is essential to reduce mortality rates; however, the manual examination is time…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nisreen Albzour , Sarah S. Lam

Immunohistochemistry (IHC) analysis is a well-accepted and widely used method for molecular subtyping, a procedure for prognosis and targeted therapy of breast carcinoma, the most common type of tumor affecting women. There are four…

Image and Video Processing · Electrical Eng. & Systems 2024-06-18 Sumit Kumar Jha , Purnendu Mishra , Shubham Mathur , Gursewak Singh , Rajiv Kumar , Kiran Aatre , Suraj Rengarajan

Prostate cancer (PCa) is one of the most common and aggressive cancers worldwide. The Gleason score (GS) system is the standard way of classifying prostate cancer and the most reliable method to determine the severity and treatment to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Santiago Toledo-Cortés , Diego H. Useche , Fabio A. González

Prostate cancer is a dominant health concern calling for advanced diagnostic tools. Utilizing digital pathology and artificial intelligence, this study explores the potential of 11 deep neural network architectures for automated Gleason…