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One of the most serious corneal disorders, keratoconus is difficult to diagnose in its early stages and can result in blindness. This illness, which often appears in the second decade of life, affects people of all sexes and races.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 AKM Enzam-Ul Haque , Golam Rabbany , Md. Siam

Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Shuang Zeng , Chee Hong Lee , Kaiwen Li , Boxu Xie , Ourui Fu , Hangzhou He , Lei Zhu , Yanye Lu , Fangxiao Cheng

Diabetic Retinopathy (DR) is a non-negligible eye disease among patients with Diabetes Mellitus, and automatic retinal image analysis algorithm for the DR screening is in high demand. Considering the resolution of retinal image is very…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Kang Zhou , Zaiwang Gu , Wen Liu , Weixin Luo , Jun Cheng , Shenghua Gao , Jiang Liu

Modern deep learning offers powerful tools for automated retinal screening, but it remains unclear how different visual model families compare in realistic multi-disease settings and under domain shift. In this work, we benchmark twelve…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Durjoy Dey , Aymane Ajbar , Yuhong Yan

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

Timely and affordable computer-aided diagnosis of retinal diseases is pivotal in precluding blindness. Accurate retinal vessel segmentation plays an important role in disease progression and diagnosis of such vision-threatening diseases. To…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Tariq M. Khan , Syed S. Naqvi , Antonio Robles-Kelly , Imran Razzak

The ability to automatically detect, classify, calculate the size, number, and grade of retinal cells and other biological objects is critically important in eye disease like age-related macular degeneration (AMD). In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2020-10-01 S. M. Hadi Hosseini , Hao Chen , Monica M. Jablonski

Diabetes Mellitus (DM) can lead to significant microvasculature disruptions that eventually causes diabetic retinopathy (DR), or complications in the eye due to diabetes. If left unchecked, this disease can increase over time and eventually…

Image and Video Processing · Electrical Eng. & Systems 2022-08-10 Meysam Tavakoli , Patrick Kelley

Retinal Vessel Segmentation is important for the diagnosis of various diseases. The research on retinal vessel segmentation focuses mainly on the improvement of the segmentation model which is usually based on U-Net architecture. In our…

Image and Video Processing · Electrical Eng. & Systems 2021-06-01 Enes Sadi Uysal , M. Şafak Bilici , B. Selin Zaza , M. Yiğit Özgenç , Onur Boyar

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Jia-Hong Huang

Alzheimer's disease (AD) is the most common long-term illness in elderly people. In recent years, deep learning has become popular in the area of medical imaging and has had a lot of success there. It has become the most effective way to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Mahin Khan Mahadi , Abdullah Abdullah , Jamal Uddin , Asif Newaz

Methods for automated retinal vessel segmentation play an important role in the treatment and diagnosis of many eye and systemic diseases. With the fast development of deep learning methods, more and more retinal vessel segmentation methods…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Gorana Gojić , Ognjen Kundačina , Dragiša Mišković , Dinu Dragan

Background/Objectives: Age-related macular degeneration, glaucoma, diabetic retinopathy (DR), diabetic macular edema, and pathological myopia affect hundreds of millions of people worldwide. Early screening for these diseases is essential,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Ananya Raghu , Anisha Raghu , Alice S. Tang , Yannis M. Paulus , Tyson N. Kim , Tomiko T. Oskotsky

In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy most of the data, while most classes have rarely few samples), which results in a challenging imbalance learning scenario. For…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Lie Ju , Xin Wang , Lin Wang , Tongliang Liu , Xin Zhao , Tom Drummond , Dwarikanath Mahapatra , Zongyuan Ge

The status of retinal arteriovenous crossing is of great significance for clinical evaluation of arteriolosclerosis and systemic hypertension. As an ophthalmology diagnostic criteria, Scheie's classification has been used to grade the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-02 Liangzhi Li , Manisha Verma , Bowen Wang , Yuta Nakashima , Hajime Nagahara , Ryo Kawasaki

Background: Type 2 diabetes mellitus (T2DM) is increasingly recognised as a systemic disease characterised by coordinated dysfunction across metabolic, renal, lipid, and inflammatory pathways. Existing clinical assessments often fail to…

Machine Learning · Computer Science 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

Towards automated retinal screening, this paper makes an endeavor to simultaneously achieve pixel-level retinal lesion segmentation and image-level disease classification. Such a multi-task approach is crucial for accurate and clinically…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Qijie Wei , Xirong Li , Weihong Yu , Xiao Zhang , Yongpeng Zhang , Bojie Hu , Bin Mo , Di Gong , Ning Chen , Dayong Ding , Youxin Chen

Leveraging multiple partially labeled datasets to train a model for multiple retinal disease screening reduces the reliance on fully annotated datasets, but remains challenging due to significant domain shifts across training datasets from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Boyi Zheng , Qing Liu

Deep learning is currently the state-of-the-art for automated detection of referable diabetic retinopathy (DR) from color fundus photographs (CFP). While the general interest is put on improving results through methodological innovations,…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Tomás Castilla , Marcela S. Martínez , Mercedes Leguía , Ignacio Larrabide , José Ignacio Orlando