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Wearable human activity sensors developed in the past decade show a distinct trend of becoming thinner and more imperceptible while retaining their electrical qualities, with graphene e-tattoos, as the ultimate example. A persistent…

High resolution nanoscale imaging in liquid environments is crucial for studying molecular interactions in biological and chemical systems. In particular, electron microscopy is the gold-standard tool for nanoscale imaging, but its…

Soft Condensed Matter · Physics 2015-07-20 Wayne Yang , Yuning Zhang , Michael Hilke , Walter Reisner

Genetic analysis methods are foundational to advancing personalized and preventative medicine, accelerating disease diagnostics, and monitoring the health of organisms and ecosystems. Current nucleic acid technologies such as polymerase…

We have developed a novel, all-electronic biosensor for opioids that consists of an engineered mu opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand…

What level of scientific knowledge has been gained against COVID-19 during the months of the pandemic? Are current technologies able to keep up with the advances in virology research? Historically, disease outbreaks due to pathogenic…

Applied Physics · Physics 2020-11-05 Giuseppina Simone

The development of next generation medicines demand more sensitive and reliable label free sensing able to cope with increasing needs of multiplexing and shorter times to results. Field effect transistor-based biosensors emerge as one of…

Applied Physics · Physics 2019-05-22 Serena Rollo , Dipti Rani , Renaud Leturcq , Wouter Olthuis , César Pascual García

A major practical barrier for implementing carbon-based electrode arrays with high device-packing density is to ensure large, predictable, and homogeneous sensitivities across the array. Overcoming this barrier depends on quantitative…

Applied Physics · Physics 2018-06-26 Ting Wu , Abdullah Alharbi , Roozbeh Kiani , Davood Shahrjerdi

Scalable production of all-electronic DNA biosensors with high sensitivity and selectivity is a critical enabling step for research and applications associated with detection of DNA hybridization. We have developed a scalable and very…

Applied Physics · Physics 2017-08-31 Jinglei Ping , Ramya Vishnubhotla , Amey Vrudhula , A. T. Charlie Johnson

The high flexibility, impermeability and strength of graphene membranes are key properties that can enable the next generation of nanomechanical sensors. However, for capacitive pressure sensors the sensitivity offered by a single suspended…

Label-free biosensors are important tools for clinical diagnostics and for studying biology at the single molecule level. The development of optical label-free sensors has allowed extreme sensitivity, but can expose the biological sample to…

This paper introduces a perspective approach for simulating a memristive sensor tailored for low power biological analyte detection. The necessity for such innovation stems from the increasing demand for efficient biosensing technologies…

Applied Physics · Physics 2024-08-13 Manel Bouzouita , Fakhreddine Zayer , Hamdi Belgacem

Graphene solution-gated field-effect transistors (SGFETs) are a promising platform for the recording of cell action potentials due to the intrinsic high signal amplification of graphene transistors. In addition, graphene technology fulfils…

Quantum biosensors offer a promising route to overcome the sensitivity and specificity limitations of conventional biosensing technologies. Their ability to detect biochemical signals at extremely low concentrations makes them strong…

Optics · Physics 2025-08-05 Yasaman Torabi , Shahram Shirani , James P. Reilly

Atomically thin materials such as graphene are uniquely responsive to charge transfer from adjacent materials, making them ideal charge transport layers in phototransistor devices. Effective implementation of organic semiconductors as a…

Biosensors are an essential tool for medical diagnostics, environmental monitoring and food safety. Typically, biosensors are designed to detect specific analytes through functionalization with the appropriate capture agents. However, the…

Medical Physics · Physics 2023-09-26 Simon J. Ward , Tengfei Cao , Xiang Zhou , Catie Chang , Sharon M. Weiss

Due to its ultrahigh electron transmissivity in a wide electron energy range, molecular impermeability, high electrical conductivity and excellent mechanical stiffness the suspended graphene membranes appear to be a nearly ideal window…

Materials Science · Physics 2015-06-11 Joshua D. Stoll , Andrei Kolmakov

In this paper we present the design and fabrication of a portable device for environmental monitoring applications. This novel hand-held apparatus monitors the changes in the resistance of a sensing surface with a high accuracy and…

Electronic DNA sequencing using two-dimensional (2D) materials such as graphene has recently emerged as the next-generation of DNA sequencing technology. Owing to its commercial availability and remarkable physical and conductive…

Mesoscale and Nanoscale Physics · Physics 2022-01-05 Matthew B. Henry , Mukesh Tumbapo , Kolby Wilson , Benjamin O. Tayo

Nanomechanical systems offer a versatile platform for both fundamental science and industrial applications. Resonating vibration has been demonstrated to enable an ultrasensitive detection of various physical quantities, with emerging…

Sensors that are able to detect and track single unlabelled biomolecules are an important tool both to understand biomolecular dynamics and interactions at nanoscale, and for medical diagnostics operating at their ultimate detection limits.…

Optics · Physics 2016-11-15 N. P. Mauranyapin , L. S. Madsen , M. A. Taylor , M. Waleed , W. P. Bowen