Related papers: Monitoring hemolysis continuously in real time
The red blood cells or erythrocytes are biconcave shaped cells and consist mostly in a membrane delimiting a cytosol with a high concentration in hemoglobin. This membrane is highly deformable and allows the cells to go through narrow…
We consider real-time timely tracking of infection status (e.g., covid-19) of individuals in a population. In this work, a health care provider wants to detect infected people as well as people who have recovered from the disease as quickly…
The flow dynamics of red blood cells in vivo in blood capillaries and in vitro in microfluidic channels is complex. Cells can obtain differnet shapes such as discoid, parachute, slipper-like shapes and various intermediate states depending…
Continuous ambulatory monitoring of peripheral vascular perfusion could enable earlier detection of vascular dysfunction in individuals with diabetes mellitus and more timely management of cardiovascular disease. Clinical imaging modalities…
Runtime Monitoring is a lightweight and dynamic verification technique that involves observing the internal operations of a software system and/or its interactions with other external entities, with the aim of determining whether the system…
An erythrocytes sedimentation rate (ESR) measures how fast a blood sample sediments along a test tube in one hour in a clinical laboratory. Since elevated level of ESR is associated with inflammatory diseases, ESR is one of the routine…
We measure the dynamical mechanical properties of human red blood cells. Single cell response is measured with optical tweezers. We investigate both the stress relaxation following a fast deformation, and the effect of varying the strain…
The morphology and velocity of the pulse wave in the arteries provide meaningful information about the cardiovascular system. Nowadays, the pulse wave is usually acquired using common blood pressure cuffs at the extremities. This work…
The emergence of an epidemic evokes the need to monitor its spread and assess and validate any mitigation measures enacted by governments and administrative bodies in real time. We present here a method to observe and quantify this spread…
Monitoring physiological responses to hemodynamic stress can help in determining appropriate treatment and ensuring good patient outcomes. Physicians' intuition suggests that the human body has a number of physiological response patterns to…
Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…
Contemporary paradigm of vascular hemodynamics considers normal blood flow to be pulsatile laminar flow. Transition to turbulence can cause diseases such as atherosclerosis or brain aneurysms. Recently, we demonstrated the existence of…
A dynamic model for failures in biological organisms is proposed and studied both analytically and numerically. Each cell in the organism becomes dead under sufficiently strong stress, and is then allowed to be healed with some probability.…
Diabetes is one of the deadliest diseases in the world and affects nearly 10 percent of the global adult population. Fortunately, powerful new technologies allow for a consistent and reliable treatment plan for people with diabetes. One…
Diagnosing diseases such as leukemia or anemia requires reliable counts of blood cells. Hematologists usually label and count microscopy images of blood cells manually. In many cases, however, cells in different maturity states are…
Motivated by the reported peculiar dynamics of a red blood cell in shear flow, we develop an analytical theory for the motion of a nearly--spherical fluid particle enclosed by a visco--elastic incompressible interface in linear flows. The…
Patients with type 2 diabetes need to closely monitor blood sugar levels as their routine diabetes self-management. Although many treatment agents aim to tightly control blood sugar, hypoglycemia often stands as an adverse event. In…
A mathematical model of atherosclerosis of a blood vessel is advanced with regard for the entry of low-density lipoproteins (LDLs) into blood. For the first time, the influence of cytokines on the inflammation of a blood vessel at the…
We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…
Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…