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The self-assembly of DNA-coated colloids controlled by enzymatic reactions has the potential to enable the formation of materials with hierarchical organization and switchable configurations. However, the problem of designing such…

Most molecular diagram parsers recover chemical structure from raster images (e.g., PNGs). However, many PDFs include commands giving explicit locations and shapes for characters, lines, and polygons. We present a new parser that uses these…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Ayush Kumar Shah , Bryan Manrique Amador , Abhisek Dey , Ming Creekmore , Blake Ocampo , Scott Denmark , Richard Zanibbi

Chemically reacting flows are common in engineering, such as hypersonic flow, combustion, explosions, manufacturing processes and environmental assessments. For combustion, the number of reactions can be significant (over 100) and due to…

Machine Learning · Computer Science 2021-04-06 Thomas S. Brown , Harbir Antil , Rainald Löhner , Fumiya Togashi , Deepanshu Verma

Polynomial dynamical systems (DSs) can model a wide range of physical processes. A special subset of these DSs that can model chemical reactions under mass-action kinetics is called chemical dynamical systems (CDSs). A fundamental problem,…

Molecular Networks · Quantitative Biology 2025-08-04 Tomislav Plesa

DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important.…

Machine Learning · Computer Science 2023-11-07 Marcel Khalifa , Barak Hoffer , Orian Leitersdorf , Robert Hanhan , Ben Perach , Leonid Yavits , Shahar Kvatinsky

Computing-in-memory (CIM) architectures demonstrate superior performance over traditional architectures. To unleash the potential of CIM accelerators, many compilation methods have been proposed, focusing on application scheduling…

Hardware Architecture · Computer Science 2025-02-25 Shixin Zhao , Yuming Li , Bing Li , Yintao He , Mengdi Wang , Yinhe Han , Ying Wang

We describe a visual programming language for defining behaviors manifested by reified actors in a 2D virtual world that can be compiled into programs comprised of sequences of combinators that are themselves reified as actors. This makes…

Neural and Evolutionary Computing · Computer Science 2015-06-05 Lance R. Williams

Astrochemical modeling is needed for understanding the formation and evolution of interstellar molecules, and for extracting physical information from spectroscopic observations of interstellar clouds. The modeling usually involves handling…

Solar and Stellar Astrophysics · Physics 2021-05-05 Fujun Du

The difficulty of simulating quantum systems, well-known to quantum chemists, prompted the idea of quantum computation. One can avoid the steep scaling associated with the exact simulation of increasingly large quantum systems on…

DNA computing, a nontraditional computing mechanism, provides a feasible and effective method for solving NP-hard problems because of the vast parallelism and high-density storage of DNA molecules. Although DNA computing has been exploited…

Molecular Networks · Quantitative Biology 2022-11-17 Enqiang Zhu , Xianhang Luo , Chanjuan Liu , Xiaolong Shi , Jin Xu

Chemical reaction networks (CRNs) are a standard formalism used in chemistry and biology to reason about the dynamics of molecular interaction networks. In their interpretation by ordinary differential equations, CRNs provide a…

Quantitative Methods · Quantitative Biology 2020-07-28 Mathieu Hemery , François Fages , Sylvain Soliman

In the last few years, we have seen the transformative impact of deep learning in many applications, particularly in speech recognition and computer vision. Inspired by Google's Inception-ResNet deep convolutional neural network (CNN) for…

Machine Learning · Statistics 2018-08-15 Garrett B. Goh , Charles Siegel , Abhinav Vishnu , Nathan O. Hodas , Nathan Baker

Genome data are crucial in modern medicine, offering significant potential for diagnosis and treatment. Thanks to technological advancements, many millions of healthy and diseased genomes have already been sequenced; however, obtaining the…

Genomics · Quantitative Biology 2024-06-18 Teddy Lazebnik , Liron Simon-Keren

We introduce ppsim, a software package for efficiently simulating population protocols, a widely-studied subclass of chemical reaction networks (CRNs) in which all reactions have two reactants and two products. Each step in the dynamics…

Data Structures and Algorithms · Computer Science 2021-07-05 David Doty , Eric Severson

DNA origami is an interdisciplinary area where DNA can be used as a building block for making useful stuff at nanoscale. This work presents an open source software DNA pen (based on the recent work of Peng Yin and his group) which can be…

Emerging Technologies · Computer Science 2013-06-04 Arnav Goyal , Dixita Limbachiya , Shikhar Kumar Gupta , Foram Joshi , Sushant Pritmani , Akshita Sahai , Manish K Gupta

Chemists now routinely use software as part of their work. For example, virtual chemistry allows chemical reactions to be simulated. In particular, a selection of software is available for the visualisation of complex 3-dimensional…

Graphics · Computer Science 2013-07-25 Karl Harrison , Jonathan P. Bowen , Alice M. Bowen

Computational screening of naturally occurring proteins has the potential to identify efficient catalysts among the hundreds of millions of sequences that remain uncharacterized. Current experimental methods remain time, cost and labor…

Quantitative Methods · Quantitative Biology 2024-02-13 Peter G. Mikhael , Itamar Chinn , Regina Barzilay

Molecular structures are always depicted as 2D printed form in scientific documents like journal papers and patents. However, these 2D depictions are not machine-readable. Due to a backlog of decades and an increasing amount of these…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Youjun Xu , Jinchuan Xiao , Chia-Han Chou , Jianhang Zhang , Jintao Zhu , Qiwan Hu , Hemin Li , Ningsheng Han , Bingyu Liu , Shuaipeng Zhang , Jinyu Han , Zhen Zhang , Shuhao Zhang , Weilin Zhang , Luhua Lai , Jianfeng Pei

Computer Aided Design systems provide tools for building and manipulating models of solid objects. Some also provide access to programming languages so that parametrised designs can be expressed. There is a sharp distinction, therefore,…

Logic in Computer Science · Computer Science 2007-05-23 Omid Banyasad , Philip T. Cox

We develop a tool that enables domain experts to quickly generate numerical solvers for emerging multi-physics phenomena starting from a high-level description based on ordinary/partial differential equations and their initial and boundary…

Computational Physics · Physics 2023-11-29 John T. Maxwell , Morad Behandish , Søren Taverniers
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