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The self-assembly of copolymeric vesicles and micelles in micromixers is studied by External Potential Dynamics (EPD) simulations -- a dynamic density functional approach that explicitly accounts for the polymer architecture both at the…

Soft Condensed Matter · Physics 2018-04-10 Simon Kessler , Klaus Drese , Friederike Schmid

Acoustically driven mixing of small fluid volumes is reported. Using surface acoustic waves on a mixer chip, conversion of those into bulk waves, and employing wave guiding effects enables us to distribute a set of "virtual sources" for…

Fluid Dynamics · Physics 2007-05-23 Andreas Rathgeber , Matthias Wassermeier , Achim Wixforth

This work describes a new microfluidic device developed for rapid screening of solubility diagrams. In several parallel channels, hundreds of nanoliter-volume droplets of a given solution are first stored with a gradual variation in the…

Soft Condensed Matter · Physics 2007-05-23 P. Laval , N. Lisai , J. -B. Salmon , M. Joanicot

Microfluidic chips provide unparalleled control over droplets and jets, which have advanced all natural sciences. However, microfluidic applications could be vastly expanded by increasing the per-channel throughput and directly exploiting…

Mixing is one of the basic functions which automated lab-on-chips require for the effective management of liquid samples. In this paper we report on the working principle, design, fabrication and experimental characterization of a…

Soft Condensed Matter · Physics 2010-12-14 M. Campisi , D. Accoto , F. Damiani , P. Dario

We present a one-dimensional shear-force-driven droplet formation model with a flux-based error estimator. The model is derived using asymptotic expansion and a front-tracking method to simulate the droplet interface. The model is then…

Numerical Analysis · Mathematics 2026-05-25 Darsh Nathawani , Matthew Knepley

In fully-developed pressure-driven flow, the spreading of a dissolved solute is enhanced in the flow direction due to transverse velocity variations in a phenomenon now commonly referred to as Taylor-Aris dispersion. It is well understood…

Fluid Dynamics · Physics 2022-10-04 Garam Lee , Alan Luner , Jeremy Marzuola , Daniel M. Harris

Spatial gradients of diffusible signalling molecules play crucial roles in controlling diverse cellular behaviour such as cell differentiation, tissue patterning and chemotaxis. In this paper, we report the design and testing of a…

Quantitative Methods · Quantitative Biology 2016-12-15 Yasushi Saka , Murray MacPherson , Claudiu V. Giuraniuc

The lack of a simple operable method for longitudinal dynamic self-assembly of particles in a microchannel is one of the main problems in applying this technology to a wide range of researches, such as biomedical engineering, material…

Fluid Dynamics · Physics 2019-11-26 Linbo Liu , Haoyan Xu , Haibo Xiu , Nan Xiang , Zhonghua Ni

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

We report the pinching of an elongated liquid droplet that is confined in a rectangular microchannel. The droplet pinching is induced by a local variation of the channel topography and can lead to its break-up. The modification of the…

We report observations of the self-assembly of coated droplets into regular clusters at the sudden expansion of a microfluidic channel. A double emulsion consisting of a regular train of coated microdroplets was created upstream of the…

Soft Condensed Matter · Physics 2020-10-19 Kerstin Schirrmann , Gabriel Cáceres-Aravena , Anne Juel

Sample preparation is an indispensable component of almost all biochemical protocols, and it involves, among others, making dilutions and mixtures of fluids in certain ratios. Recent microfluidic technologies offer suitable platforms for…

Emerging Technologies · Computer Science 2019-01-03 Sudip Poddar , Robert Wille , Hafizur Rahaman , Bhargab B. Bhattacharya

Diffusiophoresis, a ubiquitous phenomenon that induces particle transport whenever solute concentration gradients are present, was recently observed in the context of microsystems and shown to strongly impact colloidal transport (patterning…

Ethanol injection and variations of it are a class of methods where two miscible phases---one of which contains dissolved lipids---are mixed together leading to the self-assembly of lipid molecules to form liposomes. This method has been…

Soft Condensed Matter · Physics 2013-05-14 Sopan Phapal , P Sunthar

Recent experimental results indicate that mixing is enhanced by a reciprocal flow induced inside a levitated droplet with an oscillatory deformation [T. Watanabe et al. Sci. Rep. 8, 10221 (2018)]. Generally, reciprocal flow cannot convect…

Mixing in an active micromixer was achieved using Lorentz force-assisted actuation of an enameled copper wire. A single-step template-assisted soft lithography technique was used to construct the mixing chamber. The chamber had a volume of…

Applied Physics · Physics 2022-06-01 Aniket Kandalkar , Nachiket Pathak , Atharva Kulkarni , Amit Morarka

Recent works demonstrated that fiber arrays may constitue the basis of an open digital microfluidics. Various processes, such as droplet motion, fragmentation, trapping, release, mixing and encapsulation, may be achieved on fiber arrays.…

Fluid Dynamics · Physics 2015-03-13 Floriane Weyer , Marjorie Lismont , Laurent Dreesen , Nicolas Vandewalle

Micro/nanoliter droplet is capable of achieving versatile applications with tiny volume and substantial surface energy, which is a big plus over bulk liquid. Yet, the contradiction of elaborate manipulation and enough power is still a…

Applied Physics · Physics 2021-07-16 Han Zhang , Jun Yang , Yun Zhou , Jianfeng Zheng , Yong Cheng , Bichao Bai , Guoxin Zhang , Yisheng Lv

Consistency distillation methods have demonstrated significant success in accelerating generative tasks of diffusion models. However, since previous consistency distillation methods use simple and straightforward strategies in selecting…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Cunzheng Wang , Ziyuan Guo , Yuxuan Duan , Huaxia Li , Nemo Chen , Xu Tang , Yao Hu