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Related papers: A molecular communications model for drug delivery

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In diffusion-controlled drug delivery, it is possible for drug molecules to bind to the carrier material and never be released. A common way to incorporate this phenomenon into the governing mechanistic model is to include an irreversible…

Medical Physics · Physics 2024-01-19 Elliot J. Carr

Controlled drug delivery (CDD), the controlled release and delivery of therapeutic drugs inside the human body, is a promising approach to increase the efficacy of drug administration and reduce harmful side effects to the body. CDD has…

Signal Processing · Electrical Eng. & Systems 2023-05-11 Sebastian Lotter , Tom Bellmann , Sophie Marx , Mara Wesinger , Lukas Brand , Maximilian Schäfer , Dagmar Fischer , Robert Schober

In this letter, we consider a 3D molecular communication via diffusion system (MCvDS) with a single point transmitter and multiple fully-absorbing spherical receivers whose centers are distributed as a Poisson point process (PPP) in the…

Information Theory · Computer Science 2020-08-20 Nithin V. Sabu , Abhishek K. Gupta

In diffusion-based molecular communication, information particles locomote via a diffusion process, characterized by random movement and heavy tail distribution for the random arrival time. As a result, the molecular communication shows…

Emerging Technologies · Computer Science 2017-04-05 Changmin Lee , H. Birkan Yilmaz , Chan-Byoung Chae , Nariman Farsad , Andrea Goldsmith

Due to the limited capabilities of a single bio-nanomachine, complicated tasks can be performed only with the co-operation of multiple bio-nanomachines. In this work, we consider a diffusion-based molecular communication system with a…

Information Theory · Computer Science 2020-05-20 Nithin V. Sabu , Abhishek K. Gupta

In this paper, we design a drug release mechanism for dynamic time division multiple access (TDMA)-based molecular communication via diffusion (MCvD). In the proposed scheme, the communication frame is divided into several time slots over…

Signal Processing · Electrical Eng. & Systems 2019-09-02 Hamid Khoshfekr Rudsari , Nader Mokari , Mohammad Reza Javan , Eduard A. Jorswieck , Mahdi Orooji

The study of Molecular Communication(MC) is more and more prevalence, and channel model of MC plays an important role in the MC System. Since different propagation environment and modulation techniques produce different channel model, most…

Emerging Technologies · Computer Science 2016-03-14 Pengfei Lu , Yang You , Bo Liu , Zhenqiang Wu

A closer look at nature has recently brought more interest in exploring and utilizing intra-body communication networks composed of cells as intrinsic, perfectly biocompatible infrastructures to deliver therapeutics. Naturally occurring…

Signal Processing · Electrical Eng. & Systems 2022-07-06 Hamid Khoshfekr Rudsari , Mohammad Zoofaghari , Mladen Veletic , Jacob Bergsland , Ilangko Balasingham

In this paper, a simple memory limited transmitter for molecular communication is proposed, in which information is encoded in the diffusion rate of the molecules. Taking advantage of memory, the proposed transmitter reduces the ISI problem…

Information Theory · Computer Science 2014-10-30 Mohammad Movahednasab , Mehdi Soleimanifar , Amin Gohari , Masoumeh Nasiri Kenari , Urbashi Mitra

Drug-loaded hydrogels provide a means to deliver pharmaceutical agents to specific sites within the body at a controlled rate. The aim of this paper is to understand how controlled drug release can be achieved by tuning the initial…

Optimization and Control · Mathematics 2022-02-07 Matthew J. Penn , Matthew G. Hennessy

Pulmonary drug delivery systems rely on inhalation of drug-laden aerosols produced from aerosol generators such as inhalers, nebulizers etc. On deposition, the drug molecules diffuse in the mucus layer and are also subjected to mucociliary…

Tissues and Organs · Quantitative Biology 2022-01-14 Aranyak Chakravarty , Mahesh V. Panchagnula , Alladi Mohan , Neelesh A. Patankar

Molecular communication (MC) allows nanomachines to communicate and cooperate with each other in a fluid environment. The diffusion-based MC is popular but is easily constrained by the transmit distance due to the severe attenuation of…

Information Theory · Computer Science 2021-04-28 Shuo Yuan , Jiaxing Wang , Mugen Peng

The notion of synthetic molecular communication (MC) refers to the transmission of information via molecules and is largely foreseen for use within the human body, where traditional electromagnetic wave (EM)-based communication is…

Emerging Technologies · Computer Science 2025-04-16 Timo Jakumeit , Lukas Brand , Jens Kirchner , Robert Schober , Sebastian Lotter

This work presents a novel diffusion based dual-phase molecular communication system where the source leverages multiple cooperating nanomachines to improve the end-to-end reliability of communication. The Neyman-Pearson Likelihood Ratio…

Information Theory · Computer Science 2017-10-17 Neeraj Varshney , Adarsh Patel , Aditya K. Jagannatham

In this paper, a reaction-diffusion system modeling injection of a chemotherapeutic drug on the surface of a living tissue during a treatment for cancer patients is studied. The system describes the interaction of the chemotherapeutic drug…

Analysis of PDEs · Mathematics 2024-08-20 Jeff Morgan , Bao Quoc Tang , Hong-Ming Yin

Systemic drug administration often causes off-target effects limiting the efficacy of advanced therapies. Targeted drug delivery approaches increase local drug concentrations at the diseased site while minimizing systemic drug exposure. We…

In this paper, a novel time-based modulation scheme is proposed in the time-asynchronous channel for diffusion-based molecular communication systems with drift. Based on this modulation scheme, we demonstrate that the sample variance of…

Information Theory · Computer Science 2019-05-31 Qingchao Li

Molecular communication (MC) is a kind of communication technology based on biochemical molecules for internet of bio-nano things, in which the biochemical molecule is used as the information carrier for the interconnection of nano-devices.…

Information Theory · Computer Science 2017-09-15 Jiaxing Wang , Bonan Yin , Mugen Peng

We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles. The model studied here represents a typical reaction…

Biological Physics · Physics 2021-10-13 Denis S. Grebenkov , Ralf Metzler , Gleb Oshanin

Molecular communication is a biologically-inspired method of communication with attractive properties for microscale and nanoscale devices. In molecular communication, messages are transmitted by releasing a pattern of molecules at a…

Information Theory · Computer Science 2008-12-09 Andrew W. Eckford