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The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

We present a structural clustering algorithm for large-scale datasets of small labeled graphs, utilizing a frequent subgraph sampling strategy. A set of representatives provides an intuitive description of each cluster, supports the…

Databases · Computer Science 2016-10-03 Till Schäfer , Petra Mutzel

This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…

Computation · Statistics 2022-07-19 William Consagra , Martin Cole , Zhengwu Zhang

An essential premise for neuroscience brain network analysis is the successful segmentation of the cerebral cortex into functionally homogeneous regions. Resting-state functional magnetic resonance imaging (rs-fMRI), capturing the…

Neurons and Cognition · Quantitative Biology 2023-09-20 Xiaoxiao Ma , Chunzhi Yi , Zhicai Zhong , Hui Zhou , Baichun Wei , Haiqi Zhu , Feng Jiang

The structural network of the brain, or structural connectome, can be represented by fiber bundles generated by a variety of tractography methods. While such methods give qualitative insights into brain structure, there is controversy over…

Computer Vision and Pattern Recognition · Computer Science 2022-06-15 Kristen M. Campbell , Haocheng Dai , Zhe Su , Martin Bauer , P. Thomas Fletcher , Sarang C. Joshi

The topological patterns exhibited by many real-world networks motivate the development of topology-based methods for assessing the similarity of networks. However, extracting topological structure is difficult, especially for large and…

Machine Learning · Computer Science 2022-03-15 Tananun Songdechakraiwut , Bryan M. Krause , Matthew I. Banks , Kirill V. Nourski , Barry D. Van Veen

We present a data segmentation method based on a first-order density-induced consensus protocol. We provide a mathematically rigorous analysis of the consensus model leading to the stopping criteria of the data segmentation algorithm. To…

Computer Vision and Pattern Recognition · Computer Science 2022-04-25 Piotr Minakowski , Jan Peszek

Probabilistic atlases provide essential spatial contextual information for image interpretation, Bayesian modeling, and algorithmic processing. Such atlases are typically constructed by grouping subjects with similar demographic…

Machine Learning · Computer Science 2018-06-07 Yuankai Huo , Katherine Swett , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman

Brain networks, graphical models such as those constructed from MRI, have been widely used in pathological prediction and analysis of brain functions. Within the complex brain system, differences in neuronal connection strengths parcellate…

Machine Learning · Computer Science 2023-05-09 Wei Dai , Hejie Cui , Xuan Kan , Ying Guo , Sanne van Rooij , Carl Yang

Efficient extraction of useful knowledge from these data is still a challenge, mainly when the data is distributed, heterogeneous and of different quality depending on its corresponding local infrastructure. To reduce the overhead cost,…

Databases · Computer Science 2017-04-17 Nhien-An Le-Khac , M-Tahar Kechadi

As more connectome data become available, the question of how to best analyse the structure of biological neural networks becomes increasingly pertinent. In brain networks, knowing that two areas are connected is often not sufficient, as…

Neurons and Cognition · Quantitative Biology 2024-01-30 Tanguy Fardet , Emmanouil Giannakakis , Lukas Paulun , Anna Levina

We propose a new method for hierarchical clustering based on the optimisation of a cost function over trees of limited depth, and we derive a message--passing method that allows to solve it efficiently. The method and algorithm can be…

Disordered Systems and Neural Networks · Physics 2015-05-14 M. Bailly-Bechet , S. Bradde , A. Braunstein , A. Flaxman , L. Foini , R. Zecchina

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser

A prominent goal of neuroimaging studies is mapping the human brain, in order to identify and delineate functionally-meaningful regions and elucidate their roles in cognitive behaviors. These brain regions are typically represented by…

Human-Computer Interaction · Computer Science 2020-09-04 Roza G. Bayrak , Nhung Hoang , Colin B. Hansen , Catie Chang , Matthew Berger

Recent studies in neuroscience highlight the significant potential of brain connectivity networks, which are commonly constructed from functional magnetic resonance imaging (fMRI) data for brain disorder diagnosis. Traditional brain…

A large number of surface-based analyses on brain imaging data adopt some specific brain atlases to better assess structural and functional changes in one or more brain regions. In these analyses, it is necessary to obtain an anatomically…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Wen Zhang , Yalin Wang

Brain networks are typically represented by adjacency matrices, where each node corresponds to a brain region. In traditional brain network analysis, nodes are assumed to be matched across individuals, but the methods used for node matching…

Methodology · Statistics 2025-03-21 Martin Cole , Yang Xiang , Will Consagra , Anuj Srivastava , Xing Qiu , Zhengwu Zhang

After generalizing the concept of clusters to incorporate clusters that are linked to other clusters through some relatively narrow bridges, an approach for detecting patches of separation between these clusters is developed based on an…

Computer Vision and Pattern Recognition · Computer Science 2020-01-10 Luciano da F. Costa

Connections of the living human brain, on a macroscopic scale, can be mapped by a diffusion MR imaging based workflow. Since the same anatomic regions can be corresponded between distinct brains, one can compare the presence or the absence…

Neurons and Cognition · Quantitative Biology 2016-02-16 Balázs Szalkai , Csaba Kerepesi , Bálint Varga , Vince Grolmusz

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza