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This paper presents a comprehensive comparative analysis of prominent clustering algorithms K-means, DBSCAN, and Spectral Clustering on high-dimensional datasets. We introduce a novel evaluation framework that assesses clustering…

Machine Learning · Computer Science 2025-07-31 Vishnu Vardhan Baligodugula , Fathi Amsaad

Several approaches have been proposed in the literature for clustering multivariate ordinal data. These methods typically treat missing values as absent information, rather than recognizing them as valuable for profiling population…

Methodology · Statistics 2024-11-05 Alice Giampino , Antonio Canale , Bernardo Nipoti

In recent years, data dimensionality has increasingly become a concern, leading to many parameter and dimension reduction techniques being proposed in the literature. A parameter-wise co-clustering model, for data modelled via continuous…

Machine Learning · Statistics 2020-10-01 M. P. B. Gallaugher , C. Biernacki , P. D. McNicholas

Disease subtype identification (clustering) is an important problem in biomedical research. Gene expression profiles are commonly utilized to infer disease subtypes, which often lead to biologically meaningful insights into disease. Despite…

Methodology · Statistics 2016-09-27 Jiehuan Sun , Joshua L. Warren , Hongyu Zhao

Identification of clusters of co-expressed genes in transcriptomic data is a difficult task. Most algorithms used for this purpose can be classified into two broad categories: distance-based or model-based approaches. Distance-based…

Applications · Statistics 2022-09-26 Gabriel Lozano , Nadia Atallah , Michael Levine

We consider model-based clustering methods for continuous, correlated data that account for external information available in the presence of mixed-type fixed covariates by proposing the MoEClust suite of models. These models allow…

Methodology · Statistics 2021-07-15 Keefe Murphy , Thomas Brendan Murphy

In recent years, advances in high throughput sequencing technology have led to a need for specialized methods for the analysis of digital gene expression data. While gene expression data measured on a microarray take on continuous values…

Applications · Statistics 2012-02-29 Daniela M. Witten

We propose a non-parametric method to cluster mixed data containing both continuous and discrete random variables. The product space of continuous and categorical sample spaces is approximated locally by analyzing neighborhoods with cluster…

Methodology · Statistics 2013-01-29 Yawen Xu , Xin Gao , Xiaogang Wang

We investigate a clustering problem with data from a mixture of Gaussians that share a common but unknown, and potentially ill-conditioned, covariance matrix. We start by considering Gaussian mixtures with two equally-sized components and…

Machine Learning · Statistics 2021-11-30 Damek Davis , Mateo Díaz , Kaizheng Wang

It is very challenging to select informative features from tens of thousands of measured features in high-throughput data analysis. Recently, several parametric/regression models have been developed utilizing the gene network information to…

Applications · Statistics 2014-08-01 Yize Zhao , Jian Kang , Tianwei Yu

Motivation: Modelling methods that find structure in data are necessary with the current large volumes of genomic data, and there have been various efforts to find subsets of genes exhibiting consistent patterns over subsets of treatments.…

Machine Learning · Computer Science 2016-09-15 Kerstin Bunte , Eemeli Leppäaho , Inka Saarinen , Samuel Kaski

Biclustering is used for simultaneous clustering of the observations and variables when there is no group structure known \textit{a priori}. It is being increasingly used in bioinformatics, text analytics, etc. Previously, biclustering has…

Methodology · Statistics 2020-09-14 Wangshu Tu , Sanjeena Subedi

We present a new model-based integrative method for clustering objects given both vectorial data, which describes the feature of each object, and network data, which indicates the similarity of connected objects. The proposed general model…

Machine Learning · Statistics 2017-10-25 Yunchuan Kong , Xiaodan Fan

Clustering task of mixed data is a challenging problem. In a probabilistic framework, the main difficulty is due to a shortage of conventional distributions for such data. In this paper, we propose to achieve the mixed data clustering with…

Methodology · Statistics 2015-10-01 Matthieu Marbac , Christophe Biernacki , Vincent Vandewalle

A model based clustering procedure for data of mixed type, clustMD, is developed using a latent variable model. It is proposed that a latent variable, following a mixture of Gaussian distributions, generates the observed data of mixed type.…

Methodology · Statistics 2015-11-06 Damien McParland , Isobel Claire Gormley

The search for sample-variable associations is an important problem in the exploratory analysis of high dimensional data. Biclustering methods search for sample-variable associations in the form of distinguished submatrices of the data…

Genomics · Quantitative Biology 2009-10-08 Andrey A. Shabalin , Victor J. Weigman , Charles M. Perou , Andrew B. Nobel

Clustering multi-view data has been a fundamental research topic in the computer vision community. It has been shown that a better accuracy can be achieved by integrating information of all the views than just using one view individually.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Ming Yin , Weitian Huang , Junbin Gao

Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

Cluster analysis faces two problems in high dimensions: first, the `curse of dimensionality' that can lead to overfitting and poor generalization performance; and second, the sheer time taken for conventional algorithms to process large…

Quantitative Methods · Quantitative Biology 2013-09-12 Shabnam N. Kadir , Dan F. M. Goodman , Kenneth D. Harris

Multi-level modeling is an important approach for analyzing complex survey data using multi-stage sampling. However, estimation of multi-level models can be challenging when we combine several datasets with distinct hierarchies with…

Methodology · Statistics 2023-09-26 Seho Park , A James OMalley