Related papers: Neural System Identification with Spike-triggered …
The brain uses positive signals as a means of signaling. Forward interactions in the early visual cortex are also positive, realized by excitatory synapses. Only local interactions also include inhibition. Non-negative matrix factorization…
Spintronic devices offer a promising avenue for the development of nanoscale, energy-efficient artificial neurons for neuromorphic computing. It has previously been shown that with antiferromagnetic (AFM) oscillators, ultra-fast spiking…
We introduce a new method based on nonnegative matrix factorization, Neural NMF, for detecting latent hierarchical structure in data. Datasets with hierarchical structure arise in a wide variety of fields, such as document classification,…
We propose a new variant of nonnegative matrix factorization (NMF), combining separability and sparsity assumptions. Separability requires that the columns of the first NMF factor are equal to columns of the input matrix, while sparsity…
A central goal for mechanistic interpretability has been to identify the right units of analysis in large language models (LLMs) that causally explain their outputs. While early work focused on individual neurons, evidence that neurons…
Computation on a large volume of data at high speed and low power requires energy-efficient computing architectures. Spiking neural network (SNN) with bio-inspired spike-timing-dependent plasticity learning (STDP) is a promising solution…
A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…
It is a popular hypothesis in neuroscience that ganglion cells in the retina are activated by selectively detecting visual features in an observed scene. While ganglion cell firings can be predicted via data-trained deep neural nets, the…
Elucidating the neurophysiological mechanisms underlying neural pattern formation remains an outstanding challenge in Computational Neuroscience. In this paper, we address the issue of understanding the emergence of neural patterns by…
The brain has no direct access to physical stimuli, but only to the spiking activity evoked in sensory organs. It is unclear how the brain can structure its representation of the world based on differences between those noisy, correlated…
The brain is organized in a modular way, serving multiple functionalities. This multiplicity requires that both positive (e.g. excitatory, phase-coherent) and negative (e.g. inhibitory, phase-opposing) interactions take place across brain…
Single-cell RNA sequencing (scRNA-seq) is a relatively new technology that has stimulated enormous interest in statistics, data science, and computational biology due to the high dimensionality, complexity, and large scale associated with…
Biological spiking neurons with intrinsic dynamics underlie the powerful representation and learning capabilities of the brain for processing multimodal information in complex environments. Despite recent tremendous progress in spiking…
We present Supervised Deep Multimodal Matrix Factorization (SD3MF), an interpretable framework for integrative brain network analysis that generalizes Symmetric Nonnegative Matrix Tri-Factorization (SNMTF) from unsupervised single-graph…
Symmetric Nonnegative Matrix Factorization (SNMF) models arise naturally as simple reformulations of many standard clustering algorithms including the popular spectral clustering method. Recent work has demonstrated that an elementary…
Spiking Neural Networks (SNNs), inspired by the brain, are characterized by minimal power consumption and swift inference capabilities on neuromorphic hardware, and have been widely applied to various visual perception tasks. Current…
Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…
Spiking Neural Networks (SNNs) are brain-inspired, event-driven machine learning algorithms that have been widely recognized in producing ultra-high-energy-efficient hardware. Among existing SNNs, unsupervised SNNs based on synaptic…
Retinal circuitry transforms spatiotemporal patterns of light into spiking activity of ganglion cells, which provide the sole visual input to the brain. Recent advances have led to a detailed characterization of retinal activity and…
The brain efficiently performs nonlinear computations through its intricate networks of spiking neurons, but how this is done remains elusive. While nonlinear computations can be implemented successfully in spiking neural networks, this…