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Solving the electronic Schr\"odinger equation for changing nuclear coordinates provides access to the Born-Oppenheimer potential energy surface. This surface is the key starting point for almost all theoretical studies of chemical processes…

Chemical Physics · Physics 2022-01-14 Markus Reiher

Regardless of the domain, forecasting the future behaviour of a running process instance is a question of interest for decision makers, especially when multiple instances interact. Fostered by the recent advances in machine learning…

Machine Learning · Computer Science 2023-07-04 Stefan Hill , David Fitzek , Patrick Delfmann , Carl Corea

The accuracy of molecular simulations is fundamentally limited by the interatomic potentials that govern atomic interactions. Traditional potential development, which relies heavily on ab initio calculations, frequently struggles to…

Disordered Systems and Neural Networks · Physics 2025-10-16 Ruoxia Chen , Kai Yang , Morten M. Smedskjaer , N. M. Anoop Krishnan , Jaime Marian , Fabian Rosner

Theoretical concepts in condensed matter physics are typically verified and also developed by exploiting computer simulations mostly in simple models. Predictions based on these usually isotropic models are often at odds with measurement…

Soft Condensed Matter · Physics 2020-11-13 K. Koperwas , A. Grzybowski , M. Paluch

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

The use of machine learning to estimate the energy of a group of atoms, and the forces that drive them to more stable configurations, has revolutionized the fields of computational chemistry and materials discovery. In this domain, rigorous…

Chemical Physics · Physics 2025-10-28 Filippo Bigi , Marcel Langer , Michele Ceriotti

The search for new, application-specific quantum computers designed to outperform any classical computer is driven by the ending of Moore's law and the quantum advantages potentially obtainable. Photonic networks are promising examples,…

Quantum Physics · Physics 2018-04-13 B. Opanchuk , L. Rosales-Zárate , M. D. Reid , P. D. Drummond

While there have been many developments in computational probes of both strongly-correlated molecular systems and machine-learning accelerated molecular dynamics, there remains a significant gap in capabilities in simulating accurate…

Chemical Physics · Physics 2025-04-04 Yannic Rath , George H. Booth

The search for new, application-specific quantum computers designed to outperform any classical computer is driven by the ending of Moore's law and the quantum advantages potentially obtainable. Photonic networks are promising examples,…

Quantum Physics · Physics 2018-04-10 Bogdan Opanchuk , Laura Rosales-Zarate , Margaret D Reid , Peter D Drummond

VPIC is a general purpose Particle-in-Cell simulation code for modeling plasma phenomena such as magnetic reconnection, fusion, solar weather, and laser-plasma interaction in three dimensions using large numbers of particles. VPIC's…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-16 Robert Bird , Nigel Tan , Scott V. Luedtke , Stephen Lien Harrell , Michela Taufer , Brian Albright

Molecular simulation is a scientific tool dealing with challenges in material science and biology. This is reflected in a permanent development and enhancement of algorithms within scientific simulation packages. Here, we present…

The convergence of statistical learning and molecular physics is transforming our approach to modeling biomolecular systems. Physics-informed machine learning (PIML) offers a systematic framework that integrates data-driven inference with…

Biomolecules · Quantitative Biology 2025-11-11 Aaryesh Deshpande

A shadow molecular dynamics scheme for flexible charge models is presented, where the shadow Born-Oppenheimer potential is derived from a coarse-grained approximation of range-separated density functional theory. The interatomic potential,…

Chemical Physics · Physics 2023-07-27 James Goff , Yu Zhang , Christian F. A. Negre , Andrew Rohskopf , Anders M. N. Niklasson

Application of artificial intelligence (AI), and more specifically machine learning, to the physical sciences has expanded significantly over the past decades. In particular, science-informed AI, also known as scientific AI or inductive…

The implicit 2D3V particle-in-cell (PIC) code developed to study the interaction of ultrashort pulse lasers with matter [G. M. Petrov and J. Davis, Computer Phys. Comm. 179, 868 (2008); Phys. Plasmas 18, 073102 (2011)] has been parallelized…

Plasma Physics · Physics 2016-08-24 George M. Petrov , Jack Davis

Modeling and simulating the protein folding process overall remains a grand challenge in computational biology. We systematically investigate end-to-end quantum algorithms for simulating various protein dynamics with effects, such as…

Quantum Physics · Physics 2025-04-17 Zhenning Liu , Xiantao Li , Chunhao Wang , Jin-Peng Liu

The phenomenal success of physics in explaining nature and designing hardware is predicated on efficient computational models. A universal codebook of physical laws defines the computational rules and a physical system is an interacting…

Emerging Technologies · Computer Science 2021-09-14 Bahram Jalali , Achuta Kadambi , Vwani Roychowdhury

A multilevel approach to sample the potential energy surface in a path integral formalism is proposed. The purpose is to reduce the required number of ab initio evaluations of energy and forces in ab initio path integral molecular dynamics…

Computational Physics · Physics 2014-12-22 Hua Y. Geng

We introduce a general technique to compute finite temperature electronic properties by a novel covariant formulation of the electronic partition function. By using a rigorous variational upper bound to the free energy we are led to the…

Strongly Correlated Electrons · Physics 2013-06-19 Guglielmo Mazzola , Andrea Zen , Sandro Sorella

The computational cost of exact methods for quantum simulation using classical computers grows exponentially with system size. As a consequence, these techniques can only be applied to small systems. By contrast, we demonstrate that quantum…

Quantum Physics · Physics 2008-12-17 Ivan Kassal , Stephen P. Jordan , Peter J. Love , Masoud Mohseni , Alán Aspuru-Guzik
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